全文获取类型
收费全文 | 12776篇 |
免费 | 756篇 |
国内免费 | 45篇 |
专业分类
耳鼻咽喉 | 121篇 |
儿科学 | 371篇 |
妇产科学 | 254篇 |
基础医学 | 1681篇 |
口腔科学 | 313篇 |
临床医学 | 1101篇 |
内科学 | 3252篇 |
皮肤病学 | 140篇 |
神经病学 | 1195篇 |
特种医学 | 380篇 |
外国民族医学 | 1篇 |
外科学 | 1786篇 |
综合类 | 117篇 |
一般理论 | 3篇 |
预防医学 | 967篇 |
眼科学 | 225篇 |
药学 | 657篇 |
中国医学 | 33篇 |
肿瘤学 | 980篇 |
出版年
2023年 | 125篇 |
2022年 | 253篇 |
2021年 | 507篇 |
2020年 | 269篇 |
2019年 | 391篇 |
2018年 | 452篇 |
2017年 | 318篇 |
2016年 | 302篇 |
2015年 | 351篇 |
2014年 | 497篇 |
2013年 | 661篇 |
2012年 | 1041篇 |
2011年 | 967篇 |
2010年 | 607篇 |
2009年 | 454篇 |
2008年 | 760篇 |
2007年 | 780篇 |
2006年 | 662篇 |
2005年 | 696篇 |
2004年 | 619篇 |
2003年 | 494篇 |
2002年 | 520篇 |
2001年 | 169篇 |
2000年 | 124篇 |
1999年 | 137篇 |
1998年 | 86篇 |
1997年 | 74篇 |
1996年 | 71篇 |
1995年 | 72篇 |
1994年 | 61篇 |
1993年 | 45篇 |
1992年 | 75篇 |
1991年 | 52篇 |
1990年 | 63篇 |
1989年 | 41篇 |
1988年 | 53篇 |
1987年 | 38篇 |
1986年 | 59篇 |
1985年 | 46篇 |
1984年 | 40篇 |
1983年 | 52篇 |
1982年 | 41篇 |
1981年 | 30篇 |
1980年 | 32篇 |
1979年 | 32篇 |
1978年 | 21篇 |
1977年 | 30篇 |
1976年 | 23篇 |
1975年 | 21篇 |
1974年 | 29篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
991.
Gabriel Mercadal Orfila Berta Gracia García Elisabet Leiva Badosa María Perayre Badía Concepción Reynaldo Martínez Ramón Jodar Masanés 《Pharmacy World & Science》2009,31(2):224-229
Objective There is currently a controversy regarding interactions between levofloxacin and warfarin. The aim of this study was to determine
the clinical relevance of this interaction in our setting. Setting A university hospital in Barcelona, Spain. Methods We carried out a retrospective evaluation of all patients hospitalized in our hospital during the period 2000–2005, selecting
all those concomitantly treated with levofloxacin and warfarin for the study. The following data were compiled: demographic
information, concomitant medication, comorbid conditions, and relevant analytical parameters, particularly the international
normalized ratio (INR), including values taken before, during, and after concomitant administration of the two study drugs.
Patients for whom INR values during concomitant administration were not available were excluded. Differences in INR before
and during the potential interaction, and before and after the interaction were analyzed with the Wilcoxon t test using SPSS (V12.0). In addition, patients were stratified according to presence or not of toxic habits (smoking/alcohol
consumption) to investigate the possible impact of these factors on the interaction under study. Results Among the 30 patients identified, 9 were excluded because INR data during concomitant administration of warfarin and levofloxacin
were not available. Statistical analysis demonstrated significant increase in INR (P = 0.001) following addition of levofloxacin to warfarin therapy. Conclusions. The results of this study reaffirm the hypothesis that concomitant administration of levofloxacin and warfarin leads to
INR increase; hence close monitoring of INR is advisable when patients are prescribed this combination of drugs.
This paper has not been submitted elsewhere in similar form, and all authors have contributed significantly to the publication.
All authors are aware of the submission and agree with it. 相似文献
992.
Gabriel Beltrán Antonio Jiménez Carmen del Rio Sebastián Sánchez Leopoldo Martínez Marino Uceda Maria P. Aguilera 《Journal of food composition and analysis》2010,23(6):633-639
In this work the effect of genetic and agronomic factors on virgin olive oil tocopherol content and composition has been studied. For genetic effect, olive oil from thirty olive cultivars has been analyzed; for agronomic factor evaluation, three olive cultivars have been monitored during fruit ripening for three consecutive crop years. Total tocopherol content has ranged between 84 and 463 mg/kg, α-tocopherol represented more than 95%, β-tocopherol was found at very low concentrations whereas γ-tocopherol varied from 1 to 29 mg/kg. Tocopherols in virgin olive oil have a significant genetic component. Variability by crop year was due to the rainfall levels, and oils from the drier crop year (1998/99) showed the highest tocopherol content. However, this effect was cultivar-dependent, with ‘Hojiblanca’ cultivar the most affected. In general, tocopherols decreased during the ripening process, and although γ-tocopherol showed an increase for the last harvesting dates, this trend was related to the chlorophyll losses in the oil. 相似文献
993.
Farah Mushtaq Sandra Hildrew Gabriel Okugbeni Richard W Ellis 《Acta paediatrica (Oslo, Norway : 1992)》2008,97(7):985-987
Panton–Valentine leucocidin (PVL) toxin-producing strains of Staphylococcus aureus ( S. aureus ) are associated with skin abscesses and furunculosis, with necrotizing pneumonia being a relatively rare problem. Here, we describe a fatal case of necrotizing pneumonia in a 14-year-old child who presented initially with sore throat and pyrexia. He deteriorated rapidly, developing hypotension, multiple organ failure and purpura fulminans. S. aureus was isolated from the tracheal aspirate, which was found to be positive for PVL, toxic shock syndrome toxins (TSST) 1 and 2 and staphylococcal enterotoxin C (SEC). It was postulated that purpura fulminans and toxic shock syndrome were a result of the abovementioned exotoxins.
Conclusion: This case highlights the emergence of PVL-positive community-acquired S. aureus infection and association of purpura fulminans with superantigens. Practitioners should be aware of this illness in order to initiate appropriate treatment. 相似文献
Conclusion: This case highlights the emergence of PVL-positive community-acquired S. aureus infection and association of purpura fulminans with superantigens. Practitioners should be aware of this illness in order to initiate appropriate treatment. 相似文献
994.
995.
996.
997.
998.
999.
A whiplash is a sudden acceleration–deceleration of the neck and head, typically associated with a rear-end car collision that may produce injuries in the soft tissue. Often there are no objective signs or symptoms of injury, and diagnosing lasting whiplash-associated disorders (WAD) is difficult, in particular for individuals with mild or moderate injuries. This leaves a scope for compensation-seeking behaviour. The medical literature disagrees on the importance of this explanation. In this paper we trace the long-term earnings of a group of Danish individuals with mild to moderate injuries claiming compensation for having permanently lost earnings capacity and investigate if they return to their full pre-whiplash earnings when the insurance claim has been assessed. We find that about half of the claimants, those not granted compensation, return to an earnings level comparable with their pre-whiplash earnings suggesting that these individuals do not have chronic WAD in the sense that their earnings capacity is reduced. The other half, those granted compensation, experience persistent reductions in earnings relative to the case where they had not been exposed to a whiplash, even when they have a strong financial incentive to not reduce earnings. This suggests that moderate injuries tend to be chronic, and that compensation-seeking behaviour is not the main explanation for this group. We find that claimants with chronic WADs used more health care in the year prior to the whiplash than claimants with non-chronic cases. This suggests that lower initial health capital increases the risk that a whiplash causes persistent WAD. 相似文献
1000.