全文获取类型
收费全文 | 28254篇 |
免费 | 1630篇 |
国内免费 | 260篇 |
专业分类
耳鼻咽喉 | 252篇 |
儿科学 | 549篇 |
妇产科学 | 600篇 |
基础医学 | 2917篇 |
口腔科学 | 672篇 |
临床医学 | 2009篇 |
内科学 | 8159篇 |
皮肤病学 | 361篇 |
神经病学 | 2411篇 |
特种医学 | 1082篇 |
外科学 | 5226篇 |
综合类 | 54篇 |
一般理论 | 5篇 |
预防医学 | 1122篇 |
眼科学 | 526篇 |
药学 | 1665篇 |
中国医学 | 57篇 |
肿瘤学 | 2477篇 |
出版年
2024年 | 24篇 |
2023年 | 271篇 |
2022年 | 594篇 |
2021年 | 1033篇 |
2020年 | 591篇 |
2019年 | 846篇 |
2018年 | 1006篇 |
2017年 | 731篇 |
2016年 | 882篇 |
2015年 | 905篇 |
2014年 | 1226篇 |
2013年 | 1511篇 |
2012年 | 2300篇 |
2011年 | 2185篇 |
2010年 | 1255篇 |
2009年 | 1208篇 |
2008年 | 1892篇 |
2007年 | 1829篇 |
2006年 | 1727篇 |
2005年 | 1717篇 |
2004年 | 1611篇 |
2003年 | 1374篇 |
2002年 | 1245篇 |
2001年 | 142篇 |
2000年 | 137篇 |
1999年 | 180篇 |
1998年 | 212篇 |
1997年 | 167篇 |
1996年 | 158篇 |
1995年 | 154篇 |
1994年 | 127篇 |
1993年 | 117篇 |
1992年 | 100篇 |
1991年 | 59篇 |
1990年 | 69篇 |
1989年 | 55篇 |
1988年 | 42篇 |
1987年 | 37篇 |
1986年 | 45篇 |
1985年 | 42篇 |
1984年 | 36篇 |
1983年 | 34篇 |
1982年 | 49篇 |
1981年 | 30篇 |
1980年 | 27篇 |
1979年 | 17篇 |
1978年 | 13篇 |
1976年 | 12篇 |
1975年 | 10篇 |
1974年 | 12篇 |
排序方式: 共有10000条查询结果,搜索用时 156 毫秒
991.
Comparison of interstitial brachytherapy and surgery as primary treatments for nasal vestibule carcinomas
下载免费PDF全文
![点击此处可从《The Laryngoscope》网站下载免费的PDF全文](/ch/ext_images/free.gif)
992.
Population‐based assessment of cancer‐specific mortality after local tumour ablation or observation for kidney cancer: a competing risks analysis
下载免费PDF全文
![点击此处可从《BJU international》网站下载免费的PDF全文](/ch/ext_images/free.gif)
993.
Complications and quality of life in elderly patients with several comorbidities undergoing cutaneous ureterostomy with single stoma or ileal conduit after radical cystectomy
下载免费PDF全文
![点击此处可从《BJU international》网站下载免费的PDF全文](/ch/ext_images/free.gif)
994.
995.
Francesco Mancuso Christopher A. Dodd David W. Murray Hemant Pandit 《Journal of orthopaedics and traumatology》2016,17(3):267-275
Symptomatic osteoarthritis (OA) of the knee develops often in association with anterior cruciate ligament (ACL) deficiency. Two distinct pathologies should be recognised while considering treatment options in patients with end-stage medial compartment OA and ACL deficiency. Patients with primary ACL deficiency (usually traumatic ACL rupture) can develop secondary OA (typically presenting with symptoms of instability and pain) and these patients are typically young and active. Patients with primary end stage medial compartment OA can develop secondary ACL deficiency (usually degenerate ACL rupture) and these patients tend to be older. Treatment options in either of these patient groups include arthroscopic debridement, reconstruction of the ACL, high tibial osteotomy (HTO) with or without ACL reconstruction, unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA). General opinion is that a functionally intact ACL is a fundamental prerequisite to perform a UKA. This is because previous reports showed higher failure rates when ACL was deficient, probably secondary to wear and tibial loosening. Nevertheless in some cases of ACL deficiency with end-stage medial compartment OA, UKA has been performed in isolation and recent papers confirm good short- to mid-term outcome without increased risk of implant failure. Shorter hospital stay, fewer blood transfusions, faster recovery and significantly lower risk of developing major complications like death, myocardial infarction, stroke, deep vein thrombosis (as compared to TKA) make the UKA an attractive option, especially in the older patients. On the other hand, younger patients with higher functional demands are likely to benefit from a simultaneous or staged ACL reconstruction in addition to UKA to regain knee stability. These procedures tend to be technically demanding. The main aim of this review was to provide a synopsis of the existing literature and outline an evidence-based treatment algorithm. 相似文献
996.
URB937, a peripherally restricted inhibitor for fatty acid amide hydrolase,reduces prostaglandin E2‐induced bladder overactivity and hyperactivity of bladder mechano‐afferent nerve fibres in rats
下载免费PDF全文
![点击此处可从《BJU international》网站下载免费的PDF全文](/ch/ext_images/free.gif)
997.
Impact of stage migration and practice changes on high‐risk prostate cancer: results from patients treated with radical prostatectomy over the last two decades
下载免费PDF全文
![点击此处可从《BJU international》网站下载免费的PDF全文](/ch/ext_images/free.gif)
998.
Mario Musella Jan Apers Karl Rheinwalt Rui Ribeiro Emilio Manno Francesco Greco Michal Čierny Marco Milone Carla Di Stefano Sahin Guler Isa Mareike Van Lessen Anabela Guerra Mauro Natale Maglio Riccardo Bonfanti Radoslava Novotna Guido Coretti Luigi Piazza 《Obesity surgery》2016,26(5):933-940
Background
A retrospective study was undertaken to define the efficacy of both mini gastric bypass or one anastomosis gastric bypass (MGB/OAGB) and sleeve gastrectomy (SG) in type 2 diabetes mellitus (T2DM) remission in morbidly obese patients (pts).Methods
Eight European centers were involved in this survey. T2DM was preoperatively diagnosed in 313/3252 pts (9.62 %). In 175/313 patients, 55.9 % underwent MGB/OAGB, while in 138/313 patients, 44.1 % received SG between January 2006 and December 2014.Results
Two hundred six out of 313 (63.7 %) pts reached 1 year of follow-up. The mean body mass index (BMI) for MGB/OAGB pts was 33.1?±?6.6, and the mean BMI for SG pts was 35.9?±?5.9 (p?<?0.001). Eighty-two out of 96 (85.4 %) MGB/OAGB pts vs. 67/110 (60.9 %) SG pts are in remission (p?<?0.001). No correlation was found in the % change vs. baseline values for hemoglobin A1c (HbA1c) and fasting plasma glucose (FPG) in relation to BMI reduction, for both MGB/OAGB or SG (ΔFPG 0.7 and ΔHbA1c 0.4 for MGB/OAGB; ΔFPG 0.7 and ΔHbA1c 0.1 for SG). At multivariate analysis, high baseline HbA1c [odds ratio (OR)?=?0.623, 95 % confidence interval (CI) 0.419–0.925, p?=?0.01], preoperative consumption of insulin or oral antidiabetic agents (OR?=?0.256, 95 % CI 0.137–0.478, p?=?<0.001), and T2DM duration >10 years (OR?=?0.752, 95 % CI 0.512–0.976, p?=?0.01) were negative predictors whereas MGB/OAGB resulted as a positive predictor (OR?=?3.888, 95 % CI 1.654–9.143, p?=?0.002) of diabetes remission.Conclusions
A significant BMI decrease and T2DM remission unrelated from weight loss were recorded for both procedures if compared to baseline values. At univariate and multivariate analyses, MGB/OAGB seems to outperform significantly SG. Four independent variables able to influence T2DM remission at 12 months have been identified.999.
Marco Milone Matteo ND Di Minno Paolo Bianco Guido Coretti Mario Musella Francesco Milone 《International wound journal》2016,13(3):349-353
Pilonidal sinus surgery could, as of now, be considered a surgery tailored more to the surgeon than to the patient. In an attempt to give to surgeons an objective instrument of decision, we have evaluated which variables could be considered predictive of postoperative complications after pilonidal sinus surgery. A prospective electronic database of all patients treated for sacrococcygeal pilonidal disease was analysed. Sex, age, obesity, smoking, recurrent disease, the presence of multiple orifices and the distance between the most lateral orifice and midline were recorded and correlated with the occurrence of postoperative complications (infection and recurrence); 1006 patients were evaluated. Excision with primary mid‐line closure was performed on all the patients. Mean follow‐up was 7·3 ± 3·6 years. A total of 158 patients with postoperative complications (infection and/or recurrence) were recorded during this period. A multivariate analysis showed that, after adjusting for major clinical and demographic characteristics, only a recurrent disease [odds ratio (OR): 3·41, 95% confidence interval (CI): 1·89–6·15, P < 0·001] and the distance of lateral orifice from midline (OR: 26·3, 95% CI: 12·2–56·7, P < 0·001) were independent predictors of overall postoperative complications. Focussing on the distance from midline, the receiver operative characteristic (ROC) analysis showed that the distance of lateral orifice from midline predicted 79·2% of complications and the Youden's test identified the best cut‐off as 2·0 cm for this variable. An evidence‐based tool for deciding on the type of surgical intervention could be developed and validated by further ad hoc prospective studies evaluating our results in comparison to other different types of surgical techniques. Our results support the use of these variables as an effective way to tailor pilonidal sinus surgery to the patient, so as to obtain the best results in patient care. 相似文献
1000.
Paolo Capogrosso Luca Boeri Matteo Ferrari Eugenio Ventimiglia Giovanni La Croce Umberto Capitanio Alberto Briganti Rocco Damiano Francesco Montorsi Andrea Salonia 《Asian journal of andrology》2016,18(1):85-89
Testicular cancer (TC) is the most common solid cancer in men between the third and fourth decade of life. Due to successful treatment approaches, TC survivors (TCSs) have long life expectancy, but with numerous potential long-term sequelae, including sexual dysfunction. We investigated predictors of long-term normal sexual function (SF) recovery in TCSs. Sociodemographic, medical, and psychometric data were analyzed in 143 Caucasian-European TCSs, who underwent orchiectomy at a single institution. Health-significant comorbidities were scored with the Charlson Comorbidity Index (CCI). Patients completed the International Index of Erectile Function (IIEF). Statistical models tested the association between predictors (including age at surgery, body mass index, CCI, and adjuvant therapy: radiotherapy [RT], chemotherapy [CT], CT followed by retroperitoneal lymph node dissection [RPLND] and RPLND alone) and the long-term recovery of normal SF (defined as IIEF-erectile function [EF] ≥26, and sexual desire [SD], intercourse satisfaction [IS] orgasmic function [OF], and overall satisfaction [OS] domain scores in the upper tertiles). At a mean follow-up of 86 months, 35 (25.5%) TCSs had erectile dysfunction (ED), with 16 (11.2%) experiencing severe ED. Median time of EF recovery was 60, 60, and 70 months after CT, RT, and RPLND, respectively. Only adjuvant RT emerged as an independent predictor of nonrecovery of normal EF (HR: 0.55, P= 0.01). Neither adjuvant CT nor CT plus RPLND or RPLND alone significantly impaired the recovery of normal erections. Adjuvant therapy was not associated with impaired recovery of normal sexuality as a whole, considering the IIEF-SD, -OF, -IS, and OS domains. 相似文献