人甲胎蛋白时间分辨免疫荧光分析试剂盒的研制

目的研制人甲胎蛋白(hAFP)时间分辨免疫荧光分析(TRFIA)试剂盒.方法采用双抗体夹心法建立AFP TRFIA 试剂盒,对试剂盒的各项指标进行评价.结果试剂盒的可测范围为l～1 000 U/ml,灵敏度为0.17 U/ml,精密度良好,批内和批间的精密度分别为3.3%～5.9%,3.7%～6.5%.与CEA、CA12-5、CA19-9、CA15-3、白蛋白无交叉反应.稳定性试验表明试剂可以在4℃稳定1年,37℃稳定7 d.426份正常血清标本测试该试剂盒的正常参考值范围是0～12 U/ml.用本试剂盒与国外同类试剂盒同时检测60份血清标本,其相关系数为0.995.结论试剂盒各项指标(灵敏度、精密度、特异性、稳定性、准确度)均达到临床检测要求,可替代国外同类产品试剂盒.     

N－（4－乙氧苯基）苯甲酰胺类化合物的合成及抗炎、抗变态反应活性研究

Ｎ┐（４┐乙氧苯基）苯甲酰胺类化合物的合成及抗炎、抗变态反应活性研究周玉新１）党永红刘建飞２）徐颖刘百里（沈阳药科大学制药系，沈阳１１００１５）郑文义（东北第六制药厂，沈阳１１００４３）１９８１年，刘百里等〔１，２〕发现和研制的新药益肤酰胺，经药理实...     

319例小儿损伤和中毒外部原因分析

目的寻求小儿损伤和中毒意外事故发生的主要原因,以利于社会性的综合防治。方法将319例0~14岁小儿损伤和中 毒的外部原因分为11类,并按百分比从大到小排列,进行因素分析。结果得出损伤和中毒外部原因的排位。结论普及安全知识,特 别是增强小儿监护人和小孩的安全意识,才能减少事故的发生,。     

Relationship between refractive error and monochromatic aberrations of the eye.

PURPOSE: To examine the relationship between ametropia and optical aberrations in a population of 200 normal human eyes with refractive errors spanning the range from +5.00 to -10.00 D. METHODS: Using a reduced-eye model of ametropia, we tested the hypothesis that the optical system of the eye is uncorrelated with the degree of ametropia. These predictions were evaluated experimentally with a Shack-Hartmann aberrometer that measured the monochromatic aberrations across the central 6 mm of the dilated pupil in well-corrected, cyclopleged eyes. RESULTS: Optical theory predicted, and control experiments on a model eye verified, that Shack-Hartmann measurements of spherical aberration will vary with axial elongation of the eye even if the dioptric components of the eye are fixed. Contrary to these predictions, spherical aberration was not significantly different from emmetropic eyes. Root mean square of third-order aberrations, fourth-order aberrations, and total higher aberrations (third to 10th) in myopic and hyperopic eyes were also uncorrelated with refractive error. Astigmatic eyes tended to have larger total higher-order aberrations than nonastigmatic eyes. CONCLUSIONS: We conclude that a reduced-eye model of myopia assuming fixed optical parameters and variable axial length is not tenable.     

超声刀在腹腔镜胆囊切除术中的应用研究

目的　探讨超声刀在腹腔镜胆囊切除术中的应用价值。方法　将 86例腹腔镜胆囊切除术患者随机分为超声刀组 ( 3 4例 )与电刀组( 5 2例 ) ,分别使用超声刀与单极电刀完成手术 ,比较术中及术后的效果。结果　 86例手术顺利完成 ,无中转开腹。手术时间分别为 ( 4 5±7)min和 ( 62± 9)min(P <0 0 1) ,术中出血量分别为 ( 5± 0 .8)ml和 ( 2 0± 5 )ml(P <0 .0 1) ,术后肠道功能恢复时间分别为 ( 2 0± 4)h和 ( 2 4±6)h(P <0 0 1) ,两组均无胆瘘发生。结论　超声刀在腹腔镜胆囊切除术中较电刀更快捷 ,出血更少 ,术后恢复更快     

前锯肌下部肌皮瓣移植的应用解剖

目的：为前锯肌下部肌皮瓣移植提供解剖学基础。方法：在２５具（５０侧）成人尸体标本上，对前锯肌下部的形态、血供和神经支配进行了应用解剖学观测。结果：前锯肌下部的血供主要来自胸背动脉的前锯肌支，外径１．３±０．２ｍｍ，伴行静脉外径１．５±０．２ｍｍ，长４．９±１．１ｃｍ；由胸长神经支配，其横径为１．７±０．４ｍｍ，神经干长７．７±１．４ｃｍ。结论：以胸背血管及前锯肌支为血管蒂和胸长神经为蒂可切取前锯肌下部１２．０ｃｍ×９．０ｃｍ的肌皮瓣，修复较大创面或重建肌动力     

枸橼酸抗凝血液透析

研究解剖高危出血患者血液透析的抗凝方法－局部枸橼酸抗凝的临床应用和疗效。方法：采用１．６ｍｏｌ／Ｌ的枸橼酸钠、空心纤维透析器和普通含钙碳酸氢盐透析，观察ＲＣＡ透析对患者出血、体外循环凝血、血游离钙、总钙、Ｋ＾＋，Ｎａ＾＋，ｐＨ，ＨＣＯ＾－３，Ｓｃｒ，ＢＵＮ及血清枸橼酸浓度的影响。     

大,巨型垂体腺瘤的手术入路选择

自１９９０年以来收治直径在２－５．６ｃｍ的大、巨型垂体腺瘤３３例。依肿瘤生长形态与扩展范围将其简略分为三种类型。Ａ型：瘤体位于鞍内或侵入蝶窦；Ｂ型；瘤体呈椭圆形或哑铃向鞍上扩展，三脑室明显移位抬高；Ｃ型：瘤体巨大侵入三脑室阻塞室间孔或明显的鞍周扩展。     

A closed loop microprocessor controller for treatment of hypertension after cardiac surgery

Hypertension after cardiac surgery is common and requires accurate control by carefully regulated infusions of drugs such as sodium nitroprusside. A microprocessor-based controller has been designed to close the loop between the blood pressure response and the infusion rate of a hypotensive drug. This system has been refined by computer simulation of the blood pressure response to sodium nitroprusside and by experience gained in using the controller in eleven patients in the early recovery period after cardiac surgery. The controller was able automatically to maintain blood pressure within 10% of a specified value. Provision of sophisticated safety features in automatic drug infusion controllers is essential for patient protection.