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Piecemeal deglutition and dysphagia limit in normal subjects and in patients with swallowing disorders. 总被引:4,自引:2,他引:2 下载免费PDF全文
C Ertekin I Aydo?du N Yüceyar 《Journal of neurology, neurosurgery, and psychiatry》1996,61(5):491-496
OBJECTIVE: Before the advanced evaluation of deglutition and selection of a treatment method, objective screening methods are necessary for patients with dysphagia. In this study a new electroclinical test was established to evaluate patients with dysphagia. METHODS: This test is based on determining piecemeal deglutition; which is a physiological phenomenon occurring when a bolus of a large volume is divided into two or more parts which are swallowed successively. The combined electrophysiological and mechanical method used to record laryngeal movements detected by a piezoelectric transducer, and activities of the related submental integrated EMG (SM-EMG)-and sometimes the cricopharyngeal muscle of the upper oesophageal sphincter (CP-EMG)-were performed during swallowing. Thirty normal subjects and 66 patients with overt dysphagia of neurogenic origin were investigated after detailed clinical evaluation. Twenty patients with a potential risk of dysphagia, but who were normal clinically at the time of investigation, were also evaluated to determine the specificity of the test. All subjects were instructed to swallow doses of water, gradually increasing in quantity from 1 ml to 20 ml, and any recurrence of the signals related to swallowing within the eight seconds was accepted as a sign of dysphagia limit. RESULTS: In normal subjects as well as in the patients without dysphagia, piecemeal deglutition was never seen with less than 20 ml water. This volume was therefore accepted as the lower limit of piecemeal deglutition. In patients with dysphagia, dysphagia limits were significantly lower than those of normal subjects. CONCLUSION: The method is a highly specific and sensitive test for the objective evaluation of oropharyngeal dysphagia even in patients with suspected dysphagia of neurogenic origin. It can also be safely and simply applied in any EMG laboratory. 相似文献
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Satoshi Kaneko Hidefumi Ito Hirofumi Kusaka Terukuni Imai Tomoya Nishimura Hiroo Yoshikawa Banu Anlar Reha Kuruolu Kubilay Varli Meral Topu P. Araya C. Silva P. Piraino L. Pedraza M. E. Wegman M. Fruns Juan Idiaquez Aubrey Ku Elisabeth Lachmann Richard Tunkel Willibald Nagler Luca Padua Mauro Lomonaco Bruno Gregori Enza Maria Valente Pietro Tonali Cumhur Ertekin Nilgün Ara Burhanettin Uluda Zehra Karaca 《Muscle & nerve》1996,19(5):675-681
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Recruitment and screening policies and procedures used to establish a paid donor oocyte registry 总被引:3,自引:2,他引:1
We have reviewed the demographic characteristics of, and report
abnormalities noted in, the de-novo growth and development of a paid oocyte
donation programme. The personal profiles of all prospective oocyte donors
were reviewed. Acceptance or rejection of candidates was based upon
screening the results of medical, genetic and psychological testing. A
total of 603 candidates initially responded to our advertisement. From this
pool, 313 individuals were considered suitable and contacted by telephone.
Following further conversation, 176 women were scheduled an entry
interview. On completion of the formal screening process, 17.6% (n = 31) of
those actually interviewed were denied entry. Thus, from the initial
interested parties, only 23% of women wishing to participate in oocyte
donation were considered suitable candidates. Given the high attrition
rate, we concluded that the need for rigorous and thorough medical,
psychological and genetic testing is mandatory for the establishment of a
donor registry. Furthermore, professional counselling of prospective donors
with respect to the results of tests and the implications of test results
with respect to their future medical and reproductive health, are important
parts of providing comprehensive care.
相似文献
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