Peripheral gangrene associated with Kawasaki disease and successful management using prostacycline analogue: a case report

We report a case of child-onset Kawasaki disease that presented as a prolonged fever and manifested with coronary aneurysms and peripheral gangrene of the lower limbs. Therapy with intravenous immunoglobulins, corticosteroids, aspirin, anticoagulants, and ilomedine, a prostacyclin analogue, resulted in rapid improvement in the patient's condition without extremity loss. Those treating patients with Kawasaki disease must be aware of possible vascular ischemia in the disease process that is reversible by early intervention treatments, including the use of a prostacycline analogue, that improve quality of life.     

胎儿同种免疫性血小板减少症的产前处理

胎儿同种免疫性血小板减少症(alloimmunethrombocytopenia,AIT)是一种严重的疾病,可能引起颅内出血而导致死亡或永久性的神经系统残疾,因而对患病胎儿的产前处理显得非常重要。为此,我们就这一领域向各位专家提出如下问题并请专家们发表意见。 问题1:当一胎儿有患AIT的风险时,你会常规对胎儿取样(fetal blood sampling,FBS)进行血小板计数吗?如果是,那     

Successful Endovascular Treatment of a Left Common Carotid Artery Aneurysm Following Failed Surgery of a Right Common Carotid Artery Aneurysm

Aneurysm of the common carotid artery is a rare and serious disease requiring prompt treatment in order to avoid neurologic complications. A 39-year-old man presented with voice impairment and a pulsatile mass at the right side of his neck and was found by color Doppler examination to have bilateral common carotid artery aneurysms of unknown origin. The right-sided large aneurysm was treated with placement of an 8 mm interposition Gore-Tex graft between the right common and internal carotid arteries. The surgical graft thrombosed 7 days after the surgery but the left-sided aneurysm was successfully treated by a Jostent peripheral stent-graft. Color Doppler examination showed a patent stent and no filling of the aneurysm on his first and sixth-month follow-up. Bilateral common carotid artery aneurysm is an exceptionally unusual condition and endovascular treatment of carotid artery aneurysms with covered stents may become an effective treatment alternative for these lesions.     

The effects of zeta cypermethrin on the gills of common guppy Lebistes reticulatus

Effects of lethal and sublethal concentrations 15, 20, 26 and 35 μg/l of zeta cypermethrin on the gills of common guppies (L. reticulatus) were examined by light microscopy during 96 h exposure. The most common changes at all doses of zeta cypermethrin are the lifting of epithelial layer from gill lamellae and some necrosis. Besides the exudation, hyperplasia and the shortening of secondary lamellae were other histopathological effects. The 96 h LC₅₀ value for zeta cypermethrin to the L. reticulatus was determined 21.35 μg/l.     

Assessment of Severity in Acute Pancreatitis

Assessment of severity of acute pancreatitis (AP) is a key determinant in the management of a patient. This review evaluates the various methods of assessment: clinical assessment, biochemical tests, Ranson's and Imrie's multiple prognostic criteria, simplified prognostic criteria, APACHE II, peritoneal lavage, and computed tomography. Although all of the above criteria can identify most of the seriously ill patients, each has some drawbacks. Individual preference and available institutional facilities greatly influence the method used for prognostic assessment in AP. However, some type of predictive assessment is possible in any hospital, and should be used in the management of patients with AP.