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排序方式: 共有446条查询结果,搜索用时 15 毫秒
221.
Arnold CP 《中华放射肿瘤学杂志》1998,7(1)
上颌窦鳞癌需行颈预防性放疗吗?PaulinoAC,etal.IntJRadiatOncolBiolPhys,1997,39:283.本文作者回顾性分析了1971年~1995年行根治性治疗的上颌窦鳞癌42例,以了解颈部未行预防性治疗的颈淋巴结转移率及其... 相似文献
222.
Diffuse Vascular Ectasia of the Gastric Antrum 总被引:3,自引:0,他引:3
Robert Kruger M.D. Michael E. Ryan M.D. F.A.C.G. F.A.CP. Kenneth B. Dickson M.D. J. Francisco Nunez M.D. 《The American journal of gastroenterology》1987,82(5):421-426
Diffuse vascular ectasia of the gastric antrum may present as occult gastrointestinal blood loss and iron-deficiency anemia. Four patients are described with iron-deficiency anemia in whom characteristic lesions were found at endoscopy. As in previous reports, lesions are either angioid linear streaking of the antrum with convergence at the pylorus ("watermelon stomach") or diffuse, well-demarcated erythematous areas. Biopsy with the electrocautery forceps may show dilated ectatic mucosal vessels often containing fibrin thrombi which will establish a diagnosis. Standard biopsy techniques failed to make a diagnosis in two of the three patients in which it was attempted. Medical therapy consisted of iron replacement and transfusion as needed. In three of the four cases, symptomatic anemia recurred and required antrectomy for management of the anemia. The antrectomy specimens revealed ectatic mucosal and submucosal vessels with a fibrotic pattern involving the lamina propria. This pattern has been previously reported. One patient was treated with corticosteroids transiently with resolution of her anemia. The endoscopic appearance of this entity may mimic antral gastritis and needs to be considered in the differential diagnosis of iron-deficiency anemia from chronic gastrointestinal blood loss. 相似文献
223.
Behcet's disease and pregnancy relationship study 总被引:1,自引:0,他引:1
Marsal S; Falga C; Simeon CP; Vilardell M; Bosch JA 《Rheumatology (Oxford, England)》1997,36(2):234-238
The effects of pregnancy on the course of Behcet's disease (BD), and vice
versa, are unknown and little has been reported. We have studied three
groups of women: (1) group A included 61 pregnancies in 23 women with BD,
25 pregnancies took place in 10 patients already diagnosed (group 1A) and
36 pregnancies occurred in 13 patients before disease diagnosis (group 2A);
(2) group B included 30 females with 83 pregnancies affected by recurrent
oral ulcers (ROU); (3) group C included 20 healthy women with 61
pregnancies. We investigated the effects of BD on pregnancy and fetal
outcome, and the influence of gestation on the course of BD. A
questionnaire was used in which specific information about each pregnancy,
labour and puerperium was collected. We looked for medical confirmation in
all cases where any pathology had been identified. No significant
differences were found in the incidence of pregnancy complications between
groups. The incidence of perinatal death was also similar and neither
congenital abnormalities nor neonatal BD were observed. Only two patients
observed a flare of the disease and in two cases the diagnosis of BD was
made during the pregnancy. In our series, the outcome of pregnancy was
generally good in BD patients, disease manifestations were not consistently
worsened and fetal outcome was excellent. The first case of Budd-Chiari
syndrome during the puerperium in a BD patient is reported.
相似文献
224.
WYE POH FUNG M.D. F.R.A.CP. F.A.C.G. RAYMOND N. MURRAY M.B.B.S. F.R.A.C.P. † JOHN R. L. MASAREL M.D. F.R.C.P.A. ‡ ERIC G. C. TAN M.B.B.S. F.R.A.CS. 《The American journal of gastroenterology》1981,76(1):52-55
The plasma P3 amylase isoenzyme was determined in 25 patients with proven cholelithiasis. In six patients who had a single gallstone and normal pancreas at operation, the total plasma amylase was within normal limits and the P3 amylase isoenzyme was absent. In the remaining 19 patients who had multiple gallstones, pancreatitis was found at surgery in 10. In this group of 10 patients, the total plasma amylase was above the reference range for healthy individuals in only five (50%), while the P3 amylase isoenzyme band was detected in all 10 (100%). It is concluded that P3 amylase isoenzyme is superior to the total plasma amylase in the diagnosis of pancreatitis in patients with gallstone. 相似文献
225.
226.
227.
YB Mlombe NE Rosenberg LL Wolf CP Dzamalala K Chalulu J Chisi NJ Shaheen MC Hosseinipour CG Shores 《Malawi medical journal : the journal of Medical Association of Malawi》2015,27(3):88-92
Aim
There is a high burden of oesophageal cancer in Malawi with dismal outcomes. It is not known whether environmental factors are associated with oesophageal cancer. Without knowing this critical information, prevention interventions are not possible. The purpose of this analysis was to explore environmental factors associated with oesophageal cancer in the Malawian context.Methods
A hospital-based case-control study of the association between environmental risk factors and oesophageal cancer was conducted at Kamuzu Central Hospital in Lilongwe, Malawi and Queen Elizabeth Central Hospital in Blantyre, Malawi. Ninety-six persons with squamous cell carcinoma and 180 controls were enrolled and analyzed. These two groups were compared for a range of environmental risk factors, using logistic regression models. Unadjusted and adjusted odds ratios and 95% confidence intervals (CI) were calculated.Results
Firewood cooking, cigarette smoking, and use of white maize flour all had strong associations with squamous cell carcinoma of the oesophagus, with adjusted odds ratios of 12.6 (95% CI: 4.2–37.7), 5.4 (95% CI: 2.0–15.2) and 6.6 (95% CI: 2.3–19.3), respectively.Conclusions
Several modifiable risk factors were found to be strongly associated with squamous cell carcinoma. Research is needed to confirm these associations and then determine how to intervene on these modifiable risk factors in the Malawian context. 相似文献228.
Langendonk JG Roos JC Angus L Williams M Karstens FP de Klerk JB Maritz C Ben-Omran T Williamson C Lachmann RH Murphy E 《Journal of inherited metabolic disease》2012,35(3):419-424
In this case series we report 12 pregnancies, in women treated at four centres, illustrating some of the issues that may be encountered during pregnancy by women with inherited metabolic disease. We discuss how specific pregnancy, labour and delivery issues for mothers with methylmalonic acidemia, homocystinuria, propionic acidemia, glutaric acidemia type 1, ornithine transcarbamylase (OTC) deficiency and 3-hydroxy-3-methylglutaric(HMG)-CoA lyase deficiency were managed and the outcome for the mother and child in each case. Eight of the 12 pregnancies resulted in the successful delivery of a liveborn infant. Several women experienced decompensation of their condition during pregnancy or the post-partum period. There was one maternal death in a women with 3-hydroxy-3-methylglutaric(HMG)-CoA lyase deficiency. Pre-pregnancy counselling and co-management of high risk medical patients by obstetricians and specialist physicians with an understanding of the relationship between pregnancy and inherited metabolic disease is essential. 相似文献
229.
230.
The efficacy of intrathecal (i.t.) chemoprophylaxis was compared with cranial radiotherapy plus i.t. methotrexate (MTX) in a Southwest Oncology Group (SWOG) study accessing 408 patients from September 10, 1974, to October 29, 1976. Randomization was stratified by prognostic groups (PGs) based on age and white blood cell count at diagnosis. All received induction therapy with vincristine and prednisone (Pred); maintenance therapy consisted of daily 6-mercaptopurine and weekly MTX. Consolidation for arm 1 employed cyclophosphamide and L-asparaginase followed by biweekly 5-day courses of parenteral MTX. The first dose of each course of MTX was given i.t. in triple chemoprophylaxis (MTX, hydrocortisone, and cytosine arabinoside). During maintenance, i.t. chemoprophylaxis was bimonthly and 28-day Pred "pulses" were given every 3 mo. Arm 2 i.t. chemoprophylaxis was initiated on achievement of remission, and arm 3 i.t. on treatment day 1; both continued 1 yr. Arm 4 induction included two doses of L-asparaginase. On achievement of remission, CNS prophylaxis (radiotherapy, 2400 rad plus i.t. MTX) was given. For all, therapy was discontinued after 3 yr of continuous complete remission. Survival and the incidence of extramedullary relapse were similar for the treatments employing either i.t. chemoprophylaxis or radiotherapy plus i.t. MTX upon achievement of remission. Among poor prognosis patients, the duration of complete remission was significantly better with the regimen using i.t. chemoprophylaxis as a component of consolidation therapy than with the regimen employing i.t. chemoprophylaxis early in induction or with the treatment using radiotherapy plus i.t. MTX for CNS prophylaxis. In poor prognosis patients, the initiation of i.t. chemoprophylaxis during consolidation was also associated with hematologic remissions that were significantly better than those achieved with the treatment employing early CNS chemoprophylaxis or with the regimen using radiotherapy plus i.t. MTX. Among average prognosis patients, therapy with CNS chemoprophylaxis during consolidation, as well as the regimen employing radiotherapy and i.t. MTX for CNS prophylaxis, produced hematologic remissions that were significantly longer than those obtained with the regimen using early CNS chemoprophylaxis. Hematologic remissions of good prognosis patients who received treatment with the regimen employing i.t. chemoprophylaxis during consolidation were statistically superior when compared to the regimen employing CNS radiotherapy plus i.t. MTX. This study indicates that i.t. chemoprophylaxis may be substituted for cranial radiotherapy when utilizing effective systemic regimens. Additionally, chemoprophylaxis may be reduced from 3 to 1 yr in patients with good prognostic factors. 相似文献