全文获取类型
收费全文 | 8491篇 |
免费 | 453篇 |
国内免费 | 34篇 |
专业分类
耳鼻咽喉 | 76篇 |
儿科学 | 136篇 |
妇产科学 | 262篇 |
基础医学 | 1080篇 |
口腔科学 | 129篇 |
临床医学 | 580篇 |
内科学 | 2027篇 |
皮肤病学 | 371篇 |
神经病学 | 516篇 |
特种医学 | 327篇 |
外科学 | 1258篇 |
综合类 | 29篇 |
预防医学 | 213篇 |
眼科学 | 241篇 |
药学 | 616篇 |
中国医学 | 16篇 |
肿瘤学 | 1101篇 |
出版年
2023年 | 36篇 |
2022年 | 82篇 |
2021年 | 158篇 |
2020年 | 113篇 |
2019年 | 128篇 |
2018年 | 199篇 |
2017年 | 140篇 |
2016年 | 175篇 |
2015年 | 177篇 |
2014年 | 241篇 |
2013年 | 242篇 |
2012年 | 394篇 |
2011年 | 390篇 |
2010年 | 255篇 |
2009年 | 217篇 |
2008年 | 383篇 |
2007年 | 411篇 |
2006年 | 435篇 |
2005年 | 382篇 |
2004年 | 391篇 |
2003年 | 334篇 |
2002年 | 375篇 |
2001年 | 288篇 |
2000年 | 245篇 |
1999年 | 288篇 |
1998年 | 120篇 |
1997年 | 73篇 |
1996年 | 82篇 |
1995年 | 75篇 |
1994年 | 52篇 |
1993年 | 50篇 |
1992年 | 170篇 |
1991年 | 187篇 |
1990年 | 171篇 |
1989年 | 198篇 |
1988年 | 172篇 |
1987年 | 164篇 |
1986年 | 131篇 |
1985年 | 125篇 |
1984年 | 83篇 |
1983年 | 78篇 |
1982年 | 33篇 |
1980年 | 33篇 |
1979年 | 53篇 |
1978年 | 34篇 |
1977年 | 37篇 |
1974年 | 40篇 |
1972年 | 36篇 |
1971年 | 36篇 |
1969年 | 40篇 |
排序方式: 共有8978条查询结果,搜索用时 360 毫秒
31.
Makoto Watanabe Takashi Fujimoto Masayuki Iwano Hideo Shiiki Shinobu Nakamura 《Nihon Rinshō Men'eki Gakkai kaishi》2002,25(2):191-198
We describe the case of a 61-year-old woman diagnosed with primary Sj?gren's syndrome (SS) after an 8-year history of IgA nephropathy and a 3-year history of recurrent purpuric rashes. Her two daughters had previously been diagnosed with other autoimmune diseases. One daughter had Graves' disease and the other had Hashimoto's disease and systemic lupus erythematosus. The diagnosis of SS was made based on dryness of mucous membranes, Shirmer test, and parotid sialography. Thrombocytopenia, high platelet-aggregated IgG (PA-IgG) level, and normal megakaryocytes count in bone marrow suggested that her recurrent purpuric rashes were due to idiopathic thrombocytopenic purpura (ITP). Patients with SS may develop other autoimmune diseases. This case aids understanding of the immune pathogenesis and genetic background of SS. 相似文献
32.
Mariko Hosono H. Kobayashi Ryota Fujimoto Kazushige Tsutsui Yoshihiko Kotoura Tadao Tsuboyama Hikaru Hayashi Takashi Nakamura Junji Konishi 《Skeletal radiology》1997,26(9):525-528
Objective. To clarify the MRI features of parasymphyseal insufficiency fractures of the os pubis. Design and patients. MRI was performed in four postmenopausal women with parasymphyseal insufficiency fractures. The diagnosis was confirmed with
plain films in every patient. T1-weighted and T2-weighted images were obtained in four patients using a 1.5-T unit. Postcontrast
T1-weighted imaging was also done in three patients. Results and conclusions. MRI of pubic parasymphyseal insufficiency fracture characteristically demonstrates a hyperintense mass lesion with a hypointense
rim on T2-weighted imaging, showing peripheral and septal enhancement after contrast administration. It is important to have
this entity in mind in patients with osteoporosis, especially in patients with a history of pelvic irradiation for malignant
disease, so as not to misinterpret it as a chondroid tumor or bone metastasis. 相似文献
33.
S Nagano N Fujimoto M Kyo Y Ichikawa M Ishibashi S Takahara H Ihara M Nojima Y Kato A Hirano 《Hinyokika kiyo. Acta urologica Japonica》1992,38(9):1083-1088
A statistic analysis was carried out on the 4,956 inpatients admitted to our Department of Urology from April 1972 to December 1991. The patients included 3,399 males and 1,557 females. A total of 4,105 operations including 255 renal allotransplantations were performed on 3,590 patients. Open surgery for upper urinary tract stones has been replaced by extracorporeal shock-wave lithotripsy (ESWL) in the last three years. 相似文献
34.
35.
36.
K Fujimoto T Sakata H Etou K Fukagawa K Ookuma K Terada K Kurata 《The American journal of the medical sciences》1992,303(3):145-150
To maintain reduced body weight by behavioral therapy in moderately obese patients, body weight was measured four times daily and charted in a weekly graph. Seventy-two female patients with simple obesity were divided into two groups: 55 patients with appliance of charting of weight pattern (group-I), and 17 patients without the charting (group-II). The percentage of patients followed for 2 years was different between group-I (87%) and group-II (65%) during 2 years after completion of weight reduction therapy interviews (p less than 0.05). Forty-eight of group-I patients succeeded in decreasing their weight by 15.2 +/- 1.5 (mean +/- SEM) kg during the 6.5 +/- 0.8 months of the therapy interviews. They were followed up for 3.8 years with no rebound weight gain. Eleven patients in group-II also succeeded in decreasing their weight by 16.8 +/- 1.9 kg during 7.8 +/- 1.3 months but their body weight rebounded by 9.0 kg during the 2-year followup period. Twelve of 15 male patients with weight charting maintained reduced weight during 4.3 years. It was easier and more effective for obese patients to maintain weight graphs for the longer period than to record no weight graphs. Obese patients could themselves monitor irregular weight patterns produced by overeating and correct the irregularities in food intake and daily lifestyles. This seems to explain why the illustration of daily fluctuations of weight measurements was useful for long-term maintenance of weight reduction. 相似文献
37.
38.
39.
Koichi Tanaka Kazue Ozawa Satoshi Teramukai Yasutsugu Takada Hiroto Egawa Satoshi Kaihara Yasuhiro Fujimoto Yasuhiro Ogura Mureo Kasahara Masako Ono Hiroshi Sato Kenji Takai Masanori Fukushima Nagahiro Minato 《Liver transplantation》2006,12(5):792-800
The primed status of T cells is markedly different among liver transplant recipients, due to a lifetime of antigen exposure and reduced thymopoiesis by aging, and diseases. This study aims to characterize the preoperative immunological status of CD8+ T cell subpopulations and relate it to the outcome for liver transplant recipients. We classified 112 liver transplant recipients into 5 groups, based on hierarchical clustering of the CD8+CD45 isoform proportion of T cells. In Groups I and II (pediatric), the naive T cell proportion was more than 50%. In adult recipients, Group III was characterized by a naive T cell proportion of 50%, Group IV had the greatest effector/memory T cells (EM), and Group V had the greatest proportion of effector T cells. In Groups IV and V, the effector T cell proportion was considerably higher, and was accompanied by marked downregulation of the CD27+CD28+ subsets and upregulation of interferon gamma (IFN)-gamma, tumor necrosis factor-alpha, and perforin expression. Group V recipients tended to be complicated postoperatively, with a significantly reduced survival rate (1 yr, 66.8%) and markedly reduced Eastern Cooperative Oncology Group performance status. 相似文献
40.