全文获取类型
收费全文 | 2557019篇 |
免费 | 207980篇 |
国内免费 | 5083篇 |
专业分类
耳鼻咽喉 | 36339篇 |
儿科学 | 77697篇 |
妇产科学 | 66646篇 |
基础医学 | 358766篇 |
口腔科学 | 71282篇 |
临床医学 | 234421篇 |
内科学 | 505852篇 |
皮肤病学 | 50344篇 |
神经病学 | 218306篇 |
特种医学 | 101930篇 |
外国民族医学 | 893篇 |
外科学 | 387431篇 |
综合类 | 58948篇 |
现状与发展 | 1篇 |
一般理论 | 1260篇 |
预防医学 | 207464篇 |
眼科学 | 60527篇 |
药学 | 189455篇 |
10篇 | |
中国医学 | 4636篇 |
肿瘤学 | 137874篇 |
出版年
2019年 | 20969篇 |
2018年 | 28487篇 |
2017年 | 21991篇 |
2016年 | 24037篇 |
2015年 | 27406篇 |
2014年 | 39609篇 |
2013年 | 59522篇 |
2012年 | 81420篇 |
2011年 | 85705篇 |
2010年 | 50199篇 |
2009年 | 47745篇 |
2008年 | 80679篇 |
2007年 | 85689篇 |
2006年 | 86410篇 |
2005年 | 84541篇 |
2004年 | 81045篇 |
2003年 | 77917篇 |
2002年 | 76408篇 |
2001年 | 113982篇 |
2000年 | 117731篇 |
1999年 | 100000篇 |
1998年 | 30115篇 |
1997年 | 27345篇 |
1996年 | 27062篇 |
1995年 | 26140篇 |
1994年 | 24467篇 |
1993年 | 22681篇 |
1992年 | 80315篇 |
1991年 | 77246篇 |
1990年 | 74286篇 |
1989年 | 71571篇 |
1988年 | 66564篇 |
1987年 | 65510篇 |
1986年 | 62061篇 |
1985年 | 59126篇 |
1984年 | 45131篇 |
1983年 | 38505篇 |
1982年 | 23927篇 |
1981年 | 21324篇 |
1979年 | 41843篇 |
1978年 | 29567篇 |
1977年 | 24844篇 |
1976年 | 23310篇 |
1975年 | 24342篇 |
1974年 | 30022篇 |
1973年 | 28367篇 |
1972年 | 26507篇 |
1971年 | 24379篇 |
1970年 | 22945篇 |
1969年 | 21237篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
71.
S. Spinty H. Rogozinski G. T. Lealman J. E. Wraith 《Journal of inherited metabolic disease》2003,25(8):697-698
Summary: A female patient with isovaleric acidaemia had a successful outcome from pregnancy. 相似文献
72.
73.
Sebastian Bonner Thomas Matte Mitchell Rubin Joanne K Fagan Jennifer Ahern David Evans 《The Journal of asthma》2006,43(1):31-35
Although studies have documented underuse of controller medications and overuse of short-acting inhaled ss(2)-agonist among children with persistent asthma in disadvantaged communities, the persistence of oral ss(2)-agonist use in pediatric practice has not been studied since inhaled short-acting ss(2)-agonists became widespread. We describe medications used to treat asthma among children 3 to 5 years of age at 10 Head Start and other subsidized preschool centers in East and Central Harlem, New York City. We interviewed 149 parents/guardians of children who were identified as having probable asthma based on physician's diagnosis, persistent symptoms, hospitalization, and medication use. We classified 86 of the 149 children (58%) as having current persistent asthma. Only 15 of them (17%) were reported to have used controller medications at least 5 days/week in the last 4 weeks-only 2 of whom used inhaled corticosteroids. By contrast, 53 children (62%) used oral ss(2)-agonist in the last 4 weeks, often (72%) in conjunction with nebulized or inhaled short-acting ss(2)-agonist. Use of oral ss(2)-agonist was associated with more severe symptoms. This study documents the continued widespread use of oral ss(2)-agonist for treatment of children in a low-income community with high prevalence of asthma. 相似文献
74.
75.
A 27-year-old man was admitted with high fever and shivers eleven days after returning from vacation in Indonesia. Physical examination, laboratory values, abdominal ultrasound, and chest x-ray were not conclusive. All blood cultures yielded growth of Salmonella enterica serovar Typhi, and typhoid fever was diagnosed. Subsequently, the patient developed septic shock and pulmonary edema.In this case report epidemiological, clinical, and therapeutic aspects of typhoid fever are discussed with special emphasis on criteria for severe typhoid fever, which is treated with additional glucocorticoids. 相似文献
76.
77.
78.
79.
80.
To determine if impaired energy metabolism might contribute to some aspects of Alzheimer disease (AD), including the vulnerability of the CA1 region of the hippocampal formation and the altered cytoskeleton evident in neurofibrillary tangles, we examined the effects of metabolic poisons on neuronal damage and cytoskeletal disruption in the hippocampal formation. Intrahippocampal injection of 3-nitropropionic acid (3-NP) and malonic acid resulted in neuronal death, particularly in CA1. Cytoskeletal disruption included loss of dendritic MAP2, but sparing of axonal τ. MK-801 (a noncompetitive NMDA receptor antagonist) did not atenuate the lesions produced by intrahippocampal injection of malonate. MK-801, however, was effective against intrastriatal malonate. Acute systemic 3-NP resulted in neuronal damage and cytoskeletal disruption in the CA1 region of the hippocampal formation, including an extensive loss of MAP2 immuno-reactivity, but sparing of τ. The neuronal loss in CA1 was delayed as compared to striatum. Chronic intraventricular infusion of 3-NP produced a different pattern of neuronal damage. Loss of τ-1 immuno-reactivity was observed in CA3 and CA1 s. oriens, whereas MAP2 immunostaining was preserved. These results demonstrate that chronic and acute administration of metabolic inhibitors produce distinct patterns of neuronal damage and cytoskeletal disruption. The results further suggest a differential involvement of the NMDA receptor in malonate-induced neuronal damage in striatum as compared to the hippocampus. The pattern of neuronal damage and cytoskeletal disruption observed following acute metabolic impairment resembled some aspects of neurofibrillary pathology in AD, but did not result in τ hyperphosphorylation. 相似文献