全文获取类型
收费全文 | 98642篇 |
免费 | 6688篇 |
国内免费 | 517篇 |
专业分类
耳鼻咽喉 | 1255篇 |
儿科学 | 2333篇 |
妇产科学 | 1477篇 |
基础医学 | 12669篇 |
口腔科学 | 2322篇 |
临床医学 | 9737篇 |
内科学 | 21599篇 |
皮肤病学 | 1520篇 |
神经病学 | 9441篇 |
特种医学 | 3997篇 |
外国民族医学 | 1篇 |
外科学 | 16317篇 |
综合类 | 849篇 |
一般理论 | 197篇 |
预防医学 | 6693篇 |
眼科学 | 1868篇 |
药学 | 5965篇 |
中国医学 | 141篇 |
肿瘤学 | 7466篇 |
出版年
2023年 | 868篇 |
2022年 | 1506篇 |
2021年 | 3307篇 |
2020年 | 1840篇 |
2019年 | 2842篇 |
2018年 | 3340篇 |
2017年 | 2366篇 |
2016年 | 2558篇 |
2015年 | 2875篇 |
2014年 | 3973篇 |
2013年 | 5102篇 |
2012年 | 7737篇 |
2011年 | 7846篇 |
2010年 | 4312篇 |
2009年 | 3758篇 |
2008年 | 6458篇 |
2007年 | 6250篇 |
2006年 | 6030篇 |
2005年 | 5936篇 |
2004年 | 5351篇 |
2003年 | 4934篇 |
2002年 | 4429篇 |
2001年 | 667篇 |
2000年 | 559篇 |
1999年 | 742篇 |
1998年 | 915篇 |
1997年 | 724篇 |
1996年 | 594篇 |
1995年 | 580篇 |
1994年 | 464篇 |
1993年 | 474篇 |
1992年 | 406篇 |
1991年 | 338篇 |
1990年 | 331篇 |
1989年 | 329篇 |
1988年 | 318篇 |
1987年 | 301篇 |
1986年 | 310篇 |
1985年 | 306篇 |
1984年 | 367篇 |
1983年 | 323篇 |
1982年 | 353篇 |
1981年 | 356篇 |
1980年 | 282篇 |
1979年 | 173篇 |
1978年 | 205篇 |
1977年 | 192篇 |
1976年 | 137篇 |
1975年 | 146篇 |
1974年 | 152篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
131.
132.
133.
Steven N Singh X Charlene Tang Bramah N Singh Paul Dorian Domenic J Reda Crystal L Harris Ross D Fletcher Satish C Sharma J Edwin Atwood Alan K Jacobson H Daniel Lewis Becky Lopez Dennis W Raisch Michael D Ezekowitz 《Journal of the American College of Cardiology》2006,48(4):721-730
OBJECTIVES: The purpose of this study was to determine quality of life (QOL) and exercise performance (EP) in patients with persistent atrial fibrillation (AF) converted to sinus rhythm (SR) compared with those remaining in or reverting to AF. BACKGROUND: Restoration of SR in patients with AF improving QOL and EP remains controversial. METHODS: Patients with persistent AF were randomized double-blind to amiodarone, sotalol, or placebo. Those not achieving SR at day 28 were cardioverted and classified into SR or AF groups at 8 weeks (n = 624) and 1 year (n = 556). The QOL (SF-36), symptom checklist (SCL), specific activity scale (SAS), AF severity scale (AFSS), and EP were assessed. RESULTS: Favorable changes were seen in SR patients at 8 weeks in physical functioning (p < 0.001), physical role limitations (p = 0.03), general health (p = 0.002), and vitality (p < 0.001), and at 1 year in general health (p = 0.007) and social functioning (p = 0.02). Changes in the scores for SCL severity (p = 0.01), functional capacity (p = 0.003), and AFSS symptom burden (p < 0.001) at 8 weeks and in SCL severity (p < 0.01) and AF symptom burden (p < 0.001) at 1 year showed significant improvements in SR versus AF. Symptomatic patients were more likely to have improvement. The EP in SR versus AF was greater from baseline to 8 weeks (p = 0.01) and to 1 year (p = 0.02). The EP correlated with physical functioning and functional capacity except in the AF group at 1 year. CONCLUSIONS: In patients with persistent AF, restoration and maintenance of SR was associated with improvements in QOL measures and EP. There was a strong correlation between QOL measures and EP. 相似文献
134.
135.
136.
Daniel B. Costa Christopher A. Fisher Kenneth B. Miller German A. Pihan David P. Steensma Richard J. Gibbons Douglas R. Higgs 《European journal of haematology》2006,76(5):432-435
Abstract: We describe a patient with acquired alpha-thalassemia myelodysplastic syndrome (ATMDS). A previously healthy 66-year-old man presented with hemoglobin of 9.3 g/dL, mean corpuscular volume 59 fL, and a bone marrow aspirate with increased erythroid precursors and hypolobulated megakaryocytes. Hemoglobin H inclusions were seen in most red cells after 1% brilliant cresyl blue supravital stain of the peripheral blood. At the molecular level, we identified of a novel mutation in the most 3' exon of the ATRX gene ( C GA→ T GA substitution in codon 2407) resulting in a premature termination codon (p.R2407X). This case provides further evidence for a link between ATRX mutations and ATMDS, and suggests a possible role for the conserved Q-box element in ATRX function. 相似文献
137.
Influence of time elapsed between myocardial infarction and coronary artery bypass grafting surgery on operative mortality. 总被引:1,自引:0,他引:1
Pierre Voisine Patrick Mathieu Daniel Doyle Jean Perron Richard Baillot Gilles Raymond Jacques Métras Fran?ois Dagenais 《European journal of cardio-thoracic surgery》2006,29(3):319-323
OBJECTIVE: Optimal timing for CABG surgery after myocardial infarction (MI) remains controversial. We examined the influence of patient age and time elapsed between MI and isolated CABG surgery on operative mortality. METHODS: Perioperative data of 13,545 patients who underwent isolated CABG surgery from 1991 to 2005 were reviewed. A previous MI was found in 7219 patients, classified among groups A-E whether they underwent surgery less than 6h (A, n=26), between 6 and 24h (B, n=51), between 1 and 7 days (C, n=313), between 8 and 30 days (D, n=917), or more than 30 days (E, n=5912) after the event. Crude percentages and odds ratio estimates of operative mortality were calculated. RESULTS: In patients who had no history of MI, the mortality rate was 1.7%, while it was, respectively, 19.2, 9.8, 8.6, 3.2, and 2.4% in patients from groups A to E. Among 6589 patients over 65 years of age, 3027 had no history of MI. Their mortality was 2.4%, compared to, respectively, 35.7, 13.8, 11.3, 5.1, and 3.9% for those belonging to groups A-E. Overall odds ratio estimates of operative mortality were 3.92 (p=0.19), 5.08 (p=0.002), 4.33 (p=0.0001), 1.50 (p=0.08), and 1.18 (p=0.24) for groups A-E, respectively. CONCLUSIONS: Operative mortality is not influenced by a history of MI sustained more than 30 days prior to isolated CABG surgery, but is highly and most significantly increased between 6h and 1 week after MI, especially in older patients. That critical period should be avoided whenever possible. 相似文献
138.
139.
Louis Bernard Christophe Sadowski Daniel Monin Richard Stern Blaise Wyssa Peter Rohner Daniel Lew Pierre Hoffmeyer 《Infection control and hospital epidemiology》2004,25(6):512-514
OBJECTIVE: To determine whether bacterial cultures of the wounds of patients undergoing clean orthopedic surgery would help predict infection. METHODS: During 1 year, 1,256 cultures were performed for 1,102 patients who underwent clean orthopedic surgery. Results were analyzed to evaluate their ability to predict postoperative infection. RESULTS: The sensitivity, specificity, positive predictive value, and negative predictive value of the cultures were 38%, 92%, 7%, and 99%, respectively. CONCLUSIONS: Cultures performed during clean orthopedic surgery were not useful for predicting postoperative infection. 相似文献
140.
Images in emergency medicine 总被引:1,自引:0,他引:1