全文获取类型
收费全文 | 1863篇 |
免费 | 120篇 |
国内免费 | 10篇 |
专业分类
耳鼻咽喉 | 15篇 |
儿科学 | 26篇 |
妇产科学 | 37篇 |
基础医学 | 211篇 |
口腔科学 | 167篇 |
临床医学 | 114篇 |
内科学 | 470篇 |
皮肤病学 | 15篇 |
神经病学 | 186篇 |
特种医学 | 36篇 |
外科学 | 364篇 |
综合类 | 5篇 |
预防医学 | 67篇 |
眼科学 | 34篇 |
药学 | 127篇 |
中国医学 | 5篇 |
肿瘤学 | 114篇 |
出版年
2024年 | 3篇 |
2023年 | 14篇 |
2022年 | 31篇 |
2021年 | 77篇 |
2020年 | 47篇 |
2019年 | 56篇 |
2018年 | 51篇 |
2017年 | 65篇 |
2016年 | 60篇 |
2015年 | 70篇 |
2014年 | 83篇 |
2013年 | 120篇 |
2012年 | 149篇 |
2011年 | 153篇 |
2010年 | 102篇 |
2009年 | 93篇 |
2008年 | 151篇 |
2007年 | 141篇 |
2006年 | 147篇 |
2005年 | 93篇 |
2004年 | 76篇 |
2003年 | 58篇 |
2002年 | 50篇 |
2001年 | 12篇 |
2000年 | 10篇 |
1999年 | 15篇 |
1998年 | 6篇 |
1997年 | 5篇 |
1996年 | 5篇 |
1995年 | 4篇 |
1994年 | 2篇 |
1993年 | 4篇 |
1992年 | 6篇 |
1991年 | 3篇 |
1990年 | 2篇 |
1989年 | 11篇 |
1988年 | 2篇 |
1987年 | 2篇 |
1986年 | 3篇 |
1985年 | 3篇 |
1984年 | 1篇 |
1983年 | 1篇 |
1982年 | 1篇 |
1981年 | 1篇 |
1978年 | 1篇 |
1975年 | 1篇 |
1974年 | 2篇 |
排序方式: 共有1993条查询结果,搜索用时 78 毫秒
991.
Ritt LE Carvalho AC Feitosa GS Pinho-Filho JA Macedo CR Vilas-Boas F Andrade MV Feitosa-Filho GS Almeida AJ Barojas M Lopes RD 《Revista espa?ola de cardiología》2012,65(6):538-543
Introduction and objectives
Chagas disease is a prevalent cause of heart failure in Latin America, and its prognosis is worse than other etiologies. The Heart Failure Survival Score has been used to assess prognosis in patients with heart failure; however, this score has not yet been studied in patients with Chagas cardiopathy.Methods
The Heart Failure Survival Score was calculated in 55 patients with severe left ventricular systolic dysfunction due to Chagas disease. Correlations were assessed between the Heart Failure Survival Score and variables obtained from, cardiopulmonary exercise tests, quality-of-life measures, and 6-minute walking tests.Results
Patients were distributed among New York Heart Association classes II–IV; 89% were taking angiotensin-converting enzyme inhibitors or angiotensin receptor blockers, 62% were taking beta-blockers, 86% were taking diuretics, and 74% were taking aldosterone receptor blockers. The mean Heart Failure Survival Score was 8.75 (0.80). The score correlated well with cardiopulmonary test variables such as peak oxygen uptake (0.662; P<.01), oxygen uptake at the anaerobic threshold (0.644; P<.01), ventilation carbon dioxide efficiency slope (−0.417; P<.01), oxygen pulse (0.375; P<.01), oxygen uptake efficiency slope (0.626; P<.01), 6-minute walking test (0.370; P<.01), left ventricle ejection fraction (0.650; P=.01), and left atrium diameter (−0.377; P<.01). There was also a borderline significant correlation between the Heart Failure Survival Score and quality of life (−0.283; P<.05).Conclusions
In heart failure patients with Chagas disease, the Heart Failure Survival Score correlated well with the main prognostic functional test variables.Full English text available from:www.revespcardiol.org 相似文献992.
993.
Cervelli V Brinci L Palla L Spallone D Izzo V Curcio CB Lucarini L De Angelis B 《International wound journal》2012,9(1):70-75
The aim of our case report was to analyse the results obtained with the Matriderm® system and autologous skin grafting for the surgical treatment of skin necrosis of scrotum as a result of endovascular embolisation. We recruited one patient with scrotum skin necrosis as a result of endovascular embolisation admitted at the department of Plastic and Reconstructive Surgery, University of Rome ‘Tor Vergata’. The patient underwent Matriderm® system and autologous skin grafting for skin necrosis treatment. After a single treatment, reduction of the skin necrosis was obtained, after 30 days from the surgical treatment. Patient experienced a reduction in pain and a complete restoration of the loss in volume and quality of skin was noticed. Matriderm® system and autologous skin grafting is a simple, safe and feasible technique. When comparing this treatment with others, Matriderm® is a simpler, more economic and less time‐consuming method, and does not require sophisticated laboratory facilities. 相似文献
994.
995.
996.
997.
998.
Anna Alisi Valerio Nobili Sara Ceccarelli Nadia Panera Cristiano De Stefanis Rita De Vito 《Expert review of molecular diagnostics》2014,14(6):763-771
Non-alcoholic fatty liver disease (NAFLD) affects 3–12% of the general pediatric population. HMGB1 protein is presently considered a potent inflammatory mediator in several liver diseases, even if its role in NAFLD is still unknown in clinical studies. Here we investigated the relationships between circulating HMGB1, TGF-β and MCP-1 and liver damage in pediatric NAFLD. HMGB1, TGF-β and MCP-1 plasma levels were measured in 110 obese children with biopsy-proven NAFLD and 40 age-matched obese controls. HMGB1, TGF-β and MCP-1, ALT, AST and cholesterol plasma levels were significantly higher in NAFLD than in control children. A significant association between increased levels of HMGB1, TGF-β and MCP-1 and high degrees of fibrosis was found. In this study, we showed for the first time that circulating levels of HMGB1 were raised in children with NAFLD and strongly correlated with fibrosis and systemic inflammation. 相似文献
999.
Cristiano Spadaccio Alberto Rainer Pamela Mozeti Marcella Trombett Robert A Dion Raffaele Barbato Francesco Nappi Massimo Chello 《老年心脏病学杂志》2015,12(1):76-82
Cardiovascular aging is a physiological process gradually leading to structural degeneration and functional loss of all the cardiac and vascular components. Conduction system is also deeply influenced by the aging process with relevant reflexes in the clinical side. Age-related arrhythmias carry significant morbidity and mortality and represent a clinical and economical burden. An important and unjustly unrecognized actor in the pathophysiology of aging is represented by the extracellular matrix (ECM) that not only structurally supports the heart determining its mechanical and functional properties, but also sends a biological signaling regulating cellular function and maintaining tissue homeostasis. At the biophysical level, cardiac ECM exhibits a peculiar degree of anisotropy, which is among the main determinants of the conductive properties of the specialized electrical conduction system. Age-associated alterations of cardiac ECM are therefore able to profoundly affect the function of the conduction system with striking impact on the patient clinical conditions. This review will focus on the ECM changes that occur during aging in the heart conduction system and on their translation to the clinical scenario. Potential diagnostic and therapeutical perspectives arising from the knowledge on ECM age-associated alterations are further discussed. 相似文献
1000.
Luigi Petramala Antonio Concistrè Cristiano Marinelli Laura Zinnamosca Gino Iannucci Piernatale Lucia Giuseppe De Vincentis Claudio Letizia 《Medicine》2015,94(42)
To evaluate the diagnostic route of pheochromocytoma (PHEO) in a patient under dopaminergic treatment.A 70-year-old man with Parkinsonism and under treatment with levodopa and carbidopa came to our observation for evaluation of arterial hypertension and right adrenal mass discovered incidentally.To evaluate adrenal hormone levels we performed a dexamethasone suppression test, plasma aldosterone levels and 24-hr urinary metanephrine, which revealed elevated levels of catecholamines metabolities. 123-I-metaiodobenzylguanidine SPECT scintiscan revealed raised activity within the right adrenal gland concordant with the mass. The diagnosis of PHEO was posed and an elective laparoscopic adrenalectomy was performed; histopathological examination confirmed the PHEO diagnosis.Recently the coexistence of PHEO and Parkinsonism is a very rare association of diseases, with only 3 cases reported in literature. In this article, another case is reported and diagnostic procedures are discussed. 相似文献