全文获取类型
收费全文 | 2057篇 |
免费 | 190篇 |
国内免费 | 29篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 153篇 |
妇产科学 | 46篇 |
基础医学 | 273篇 |
口腔科学 | 101篇 |
临床医学 | 183篇 |
内科学 | 412篇 |
皮肤病学 | 65篇 |
神经病学 | 132篇 |
特种医学 | 181篇 |
外科学 | 288篇 |
综合类 | 41篇 |
预防医学 | 114篇 |
眼科学 | 40篇 |
药学 | 103篇 |
中国医学 | 10篇 |
肿瘤学 | 128篇 |
出版年
2023年 | 17篇 |
2022年 | 20篇 |
2021年 | 25篇 |
2020年 | 23篇 |
2019年 | 12篇 |
2018年 | 52篇 |
2017年 | 51篇 |
2016年 | 46篇 |
2015年 | 64篇 |
2014年 | 92篇 |
2013年 | 131篇 |
2012年 | 74篇 |
2011年 | 58篇 |
2010年 | 94篇 |
2009年 | 105篇 |
2008年 | 54篇 |
2007年 | 77篇 |
2006年 | 74篇 |
2005年 | 44篇 |
2004年 | 53篇 |
2003年 | 35篇 |
2002年 | 35篇 |
2001年 | 33篇 |
2000年 | 19篇 |
1999年 | 39篇 |
1998年 | 107篇 |
1997年 | 90篇 |
1996年 | 98篇 |
1995年 | 66篇 |
1994年 | 78篇 |
1993年 | 41篇 |
1992年 | 25篇 |
1991年 | 29篇 |
1990年 | 21篇 |
1989年 | 39篇 |
1988年 | 42篇 |
1987年 | 38篇 |
1986年 | 37篇 |
1985年 | 35篇 |
1984年 | 20篇 |
1983年 | 16篇 |
1982年 | 25篇 |
1981年 | 19篇 |
1980年 | 20篇 |
1979年 | 10篇 |
1978年 | 7篇 |
1977年 | 12篇 |
1976年 | 19篇 |
1975年 | 17篇 |
1972年 | 5篇 |
排序方式: 共有2276条查询结果,搜索用时 15 毫秒
81.
82.
Nicola Montano Fabio Papacci Beatrice Cioni Simona Gaudino Giuseppe Maria Della Pepa Giulio Conforti Rina Di Bonaventura Mariangela Novello Libero Lauriola Mario Meglio 《Journal of clinical neuroscience》2013,20(11):1605-1608
Pleomorphic xanthoastrocytoma (PXA) is a rare tumor with good prognosis after surgery. Few cases of anaplastic PXA (either de novo or secondary to transformation of a recurrent low grade PXA) have been reported. Moreover, primary anaplastic PXA with dissemination at diagnosis has been described only in two patients, to our knowledge. We report the first case of primary multicentric anaplastic PXA and discuss its atypical features and the pertinent literature. 相似文献
83.
84.
85.
G Lavie ; Y Mazur ; D Lavie ; AM Prince ; D Pascual ; L Liebes ; B Levin ; D Meruelo 《Transfusion》1995,35(5):392-400
86.
87.
88.
89.
Ermelinda Viola Sibilla Opri Ugo Moretti Roberto Leone Maria Luisa Casini Sara Ruggieri Claudia Minore Anita Conforti 《European journal of clinical pharmacology》2014,70(8):1003-1009
Purpose
The aim of this study was to analyze the cases of gynecomastia associated with α1A-adrenergic receptor antagonists (α1-ARAs) in the Italian spontaneous reporting system database (Rete Nazionale di Farmacovigilanza or RNF) and in the World Health Organization ICSRs database (VigiBase?), focusing on tamsulosin use.Methods
We analyzed the spontaneous reports of gynecomastia related to the use of α1-ARAs and collected from the RNF and from VigiBase? up to December 2012. Cases of gynecomastia have been defined as reports associated with gynecomastia according with Medical Dictionary for Regulatory Activities (MedDRA). Reporting odds ratio (ROR) and Information Component (IC) were calculated as measures of disproportionality in RNF and VigiBase?, respectively.Results
Up to December 2012, about 186,000 reports were recorded in the RNF. Among these, 902 reports of adverse drug reaction (ADR) have been associated with the use of at least one α1-ARAs. Of these, in 15 cases, gynecomastia was a listed ADR: in 10, the suspected drug was tamsulosin (in eight, it was the sole suspect); in two, doxazosin and alfuzosin, respectively; and in one, terazosin. ROR for tamsulosin was 5.3 (95 % CI 1.8, 15.7). In VigiBase?, 84 reports of gynecomastia indicated tamsulosin as suspected drug. Tamsulosin-associated gynecomastia showed the highest IC value within this class of drugs (IC 95 % 2.43).Conclusion
In this study, we highlight a possible association between gynecomastia and tamsulosin use. To our knowledge, this association has not been described before and could represent a potential signal. 相似文献90.