全文获取类型
收费全文 | 4929篇 |
免费 | 342篇 |
国内免费 | 20篇 |
专业分类
耳鼻咽喉 | 31篇 |
儿科学 | 148篇 |
妇产科学 | 105篇 |
基础医学 | 781篇 |
口腔科学 | 71篇 |
临床医学 | 402篇 |
内科学 | 1374篇 |
皮肤病学 | 125篇 |
神经病学 | 498篇 |
特种医学 | 64篇 |
外科学 | 360篇 |
综合类 | 21篇 |
一般理论 | 3篇 |
预防医学 | 470篇 |
眼科学 | 108篇 |
药学 | 300篇 |
中国医学 | 41篇 |
肿瘤学 | 389篇 |
出版年
2023年 | 79篇 |
2022年 | 154篇 |
2021年 | 273篇 |
2020年 | 121篇 |
2019年 | 176篇 |
2018年 | 197篇 |
2017年 | 137篇 |
2016年 | 159篇 |
2015年 | 181篇 |
2014年 | 216篇 |
2013年 | 284篇 |
2012年 | 421篇 |
2011年 | 450篇 |
2010年 | 172篇 |
2009年 | 170篇 |
2008年 | 296篇 |
2007年 | 251篇 |
2006年 | 243篇 |
2005年 | 217篇 |
2004年 | 219篇 |
2003年 | 185篇 |
2002年 | 195篇 |
2001年 | 24篇 |
2000年 | 17篇 |
1999年 | 26篇 |
1998年 | 30篇 |
1997年 | 32篇 |
1996年 | 24篇 |
1995年 | 21篇 |
1994年 | 14篇 |
1993年 | 17篇 |
1992年 | 19篇 |
1991年 | 12篇 |
1990年 | 8篇 |
1989年 | 17篇 |
1988年 | 9篇 |
1987年 | 12篇 |
1986年 | 7篇 |
1985年 | 9篇 |
1982年 | 15篇 |
1981年 | 10篇 |
1980年 | 7篇 |
1979年 | 9篇 |
1977年 | 6篇 |
1968年 | 6篇 |
1938年 | 8篇 |
1935年 | 5篇 |
1934年 | 5篇 |
1932年 | 5篇 |
1927年 | 7篇 |
排序方式: 共有5291条查询结果,搜索用时 93 毫秒
51.
Olga Laporta-Hoyos Júlia Ballester-Plané David Leiva Teresa Ribas Júlia Miralbell Clara Torroja-Nualart Maria Eugenia Russi Esther Toro-Tamargo Mar Meléndez-Plumed Francisca Gimeno Alfons Macaya Roser Pueyo 《European journal of paediatric neurology》2019,23(4):546-559
AimTo comprehensively describe intellectual and executive functioning (EF) in people with dyskinetic cerebral palsy (DCP), by comparing their performance with that of: 1) age- and sex-matched typically developing controls (TDC); and 2) participants with spastic cerebral palsy (SCP) matched for age, sex, term/preterm and gross motor function classification system (GMFCS).MethodThis cross-sectional study was conducted by the University of Barcelona in collaboration with five institutions. Participants were people with DCP (n = 52; 24 females, median age 20.5 y: 5mo, interquartile range [IQR] = 13.75 y: 7mo; GMFCS I–V). As comparison groups, participants with SCP (n = 20; 10 females, median age = 20.5 y: 5.5mo, IQR = 13.75 y 9mo; GMFCS I–V) and TDC (n = 52; 24 females, median age = 20 y: 4mo, IQR = 12 y 7mo) were included. Intelligence and EF were assessed using common tests in all participants.ResultsBoth CP groups had lower intelligence than TDC and performed poorer in almost all EF tasks. Intelligence was higher in DCP than SCP (z = ?2.51, p = 0.01). Participants with DCP also performed significantly better in goal-setting tasks (z = 2.27, p = 0.03) and information processing (z = ?2.54, p = 0.01) than those with SCP.ConclusionPeople with DCP present lower general intellectual functioning and poorer EF across multiple domains than typically developing controls. People with DCP have higher general intellectual functioning and better EF than people with SCP when levels of motor severity are similar. 相似文献
52.
Impact of a change in protected environment on the occurrence of severe bacterial and fungal infections in children undergoing hematopoietic stem cell transplantation
下载免费PDF全文
![点击此处可从《European journal of haematology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
53.
Azra Dad Clara H. Jeong Justin A. Pals Elizabeth D. Wagner Michael J. Plewa 《Environmental and molecular mutagenesis》2013,54(8):629-637
Monohaloacetic acids (monoHAAs) are a major class of drinking water disinfection by‐products (DBPs) and are cytotoxic, genotoxic, mutagenic, and teratogenic. We propose a model of toxic action based on monoHAA‐mediated inhibition of glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) as a target cytosolic enzyme. This model predicts that GAPDH inhibition by the monoHAAs will lead to a severe reduction of cellular ATP levels and repress the generation of pyruvate. A loss of pyruvate will lead to mitochondrial stress and genomic DNA damage. We found a concentration‐dependent reduction of ATP in Chinese hamster ovary cells after monoHAA treatment. ATP reduction per pmol monoHAA followed the pattern of iodoacetic acid (IAA) > bromoacetic acid (BAA) >> chloroacetic acid (CAA), which is the pattern of potency observed with many toxicological endpoints. Exogenous supplementation with pyruvate enhanced ATP levels and attenuated monoHAA‐induced genomic DNA damage as measured with single cell gel electrophoresis. These data were highly correlated with the SN2 alkylating potentials of the monoHAAs and with the induction of toxicity. The results from this study strongly support the hypothesis that GAPDH inhibition and the possible subsequent generation of reactive oxygen species is linked with the cytotoxicity, genotoxicity, teratogenicity, and neurotoxicity of these DBPs. Environ. Mol. Mutagen. 54:629–637, 2013. © 2013 Wiley Periodicals, Inc. 相似文献
54.
55.
56.
57.
Emmanuel Ochefije Ngbede Mashood Abiola Raji Clara N. Kwanashie Chukwudi Okolocha Nanven Abraham Maurice Emmanuella Nguavese Akange Leslie Ewache Odeh 《亚太热带病杂志(英文版)》2012,2(5):367-369
ObjectiveTo assess the occurrence of Leptospira spp serovar Hardjo among Zebu cattle in some livestock producing areas of Kaduna State, Nigeria.MethodsSera samples were obtained from 164 Zebu breed of cattle above one year osf age in seven cattle farms were screened for antibodies to Leptospira spp. serovar Hardjo using Enzyme linked immunosorbent assay (ELISA).ResultsAntibodies to Leptospira spp. serovar Hardjo were detected in eighteen (10.98%) out of the 164 animals sampled. There was no significant difference (P>0.05) in seropositivity between the different age groups or between different Zebu breeds.ConclusionThe presence of Leptospirosis among the Zebu breeds of cattle may poses a threat to livestock production and has public health implication due to its zoonotic potential. 相似文献
58.
Efficacy of the Otago Exercise Programme to reduce falls in community‐dwelling adults aged 65–80 years old when delivered as group or individual training
下载免费PDF全文
![点击此处可从《Journal of advanced nursing》网站下载免费的PDF全文](/ch/ext_images/free.gif)
59.
60.
Clara Benedetta Conti Mariangela Giunta Daniele Gridavilla Dario Conte Mirella Fraquelli 《Ultrasound in medicine & biology》2017,43(4):725-734
Crohn's disease (CD) is an inflammatory chronic bowel disorder; it can involve the whole gastrointestinal tract, but its localization in the ileum or colon is most common. The reference standard for the diagnosis of CD is ileocolonoscopy with histologic assessment. The reference standard for the detection of any complications is surgery. However, imaging techniques have an important role both in the detection/localization of CD and in the follow-up of CD patients. In the last few years, the technical development of ultrasound equipment, the advent of new technologies such as elastography and mostly the increased expertise of sonographers have boosted the role of bowel ultrasound in assessment of the gastrointestinal tract. In fact, bowel ultrasound is particularly attractive thanks to its widespread availability, non-invasiveness, low cost and good reproducibility, as it can be easily repeated during follow-up. The aim of this article is to provide an extensive overview of the actual role of bowel ultrasound in the detection and follow-up of patients with CD. 相似文献