全文获取类型
收费全文 | 31850篇 |
免费 | 2212篇 |
国内免费 | 460篇 |
专业分类
耳鼻咽喉 | 644篇 |
儿科学 | 513篇 |
妇产科学 | 683篇 |
基础医学 | 4501篇 |
口腔科学 | 485篇 |
临床医学 | 2615篇 |
内科学 | 7244篇 |
皮肤病学 | 972篇 |
神经病学 | 2195篇 |
特种医学 | 1632篇 |
外科学 | 4283篇 |
综合类 | 529篇 |
一般理论 | 15篇 |
预防医学 | 1307篇 |
眼科学 | 924篇 |
药学 | 2760篇 |
中国医学 | 339篇 |
肿瘤学 | 2881篇 |
出版年
2023年 | 213篇 |
2022年 | 580篇 |
2021年 | 993篇 |
2020年 | 499篇 |
2019年 | 820篇 |
2018年 | 951篇 |
2017年 | 680篇 |
2016年 | 906篇 |
2015年 | 1241篇 |
2014年 | 1471篇 |
2013年 | 1682篇 |
2012年 | 2477篇 |
2011年 | 2537篇 |
2010年 | 1530篇 |
2009年 | 1311篇 |
2008年 | 1856篇 |
2007年 | 1773篇 |
2006年 | 1597篇 |
2005年 | 1528篇 |
2004年 | 1287篇 |
2003年 | 1247篇 |
2002年 | 1134篇 |
2001年 | 755篇 |
2000年 | 679篇 |
1999年 | 637篇 |
1998年 | 247篇 |
1997年 | 226篇 |
1996年 | 200篇 |
1995年 | 171篇 |
1994年 | 150篇 |
1993年 | 98篇 |
1992年 | 305篇 |
1991年 | 230篇 |
1990年 | 264篇 |
1989年 | 257篇 |
1988年 | 243篇 |
1987年 | 198篇 |
1986年 | 177篇 |
1985年 | 161篇 |
1984年 | 140篇 |
1983年 | 111篇 |
1982年 | 79篇 |
1981年 | 71篇 |
1980年 | 69篇 |
1979年 | 124篇 |
1978年 | 82篇 |
1977年 | 66篇 |
1975年 | 59篇 |
1974年 | 53篇 |
1972年 | 49篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
991.
Hideki Osawa Junichi Hasegawa Kazuma Yamakawa Nobuki Matsunami Shoki Mikata Junzo Shimizu Yong Kook Kim Hirotaka Morishima Masaki Hirota Yoshihito Souma Ho Min Kim Genta Sawada Riichiro Nezu 《Surgery today》2013,43(7):745-750
Purpose
Pinch-off syndrome (POS) is a serious complication encountered during the long-term management of totally implantable access ports (TIAPs). The aim of this study was to examine the effect of ultrasound-guided infraclavicular axillary vein puncture to avoid POS in patients with long-term use of a TIAP.Methods
This was a retrospective review of 207 consecutive TIAPs: one hundred devices implanted using an anatomical landmark technique were used as historical controls (Landmark group), while 107 devices were implanted using an ultrasound (US)-guided puncture method (US group). The pinch-off grade (POG) was determined using chest X-ray findings following the definition of Hinke, and the progression of POG during the follow-up period of the Landmark and US groups was compared.Results
Sixteen cases in the Landmark group were POG-1 and 3 were POG-2, while all cases in the US group were POG-0 at the time of venipuncture (p < 0.001). Eleven patients in the Landmark group showed some degree of progression of the POG during the follow-up period. In contrast, there were no cases showing progression of the POG in the US group (p = 0.002).Conclusions
US-guided infraclavicular axillary vein puncture was found to effectively make it possible to avoid POS for the long-term management of TIAPs, as well as at the time of implantation. 相似文献992.
993.
Joonchul Jang M.D. Seong‐Ho Jeong M.D. Ph.D. Seung‐Kyu Han M.D. Ph.D. Woo‐Kyung Kim M.D. Ph.D. 《Microsurgery》2013,33(6):482-486
Reconstruction of extensive abdominal wall defects is a challenge for reconstructive surgeons. In this report, a case of reconstruction of a large abdominal wall defect using an eccentric perforator‐based pedicled anterolateral thigh (ALT) flap is presented. A 30‐year‐old man presented with recurrent desmoid‐type fibromatosis in the abdominal wall. The recurrent tumor was radically excised, and the en bloc excision resulted in a full‐thickness, large abdominal wall defect (25 cm × 20 cm). An eccentric perforator‐based pedicled ALT flap, including wide fascial extension, was transferred to the abdominal defect; fascial portions were sutured to the remnant abdominal fascia. Plication of the fascia along the sutured portion was performed to relieve the skin tension between the flap and the marginal skin of the abdominal defect. Eight months after surgery, the reconstructed abdomen had an acceptable esthetic appearance without tumor recurrence or hernia. The use of an eccentric perforator‐based pedicled ALT flap may be an alternative method for the reconstruction of extensive abdominal wall defects. © 2013 Wiley Periodicals, Inc. Microsurgery 33:482–486, 2013. 相似文献
994.
995.
996.
Jeremy Yuen Chun Teoh Ning Hong Chan Ho Yuen Cheung Simon See Ming Hou Chi-Fai Ng 《International urology and nephrology》2013,45(4):975-977
We report a case of a 60-year-old woman who had a delayed presentation of duodenal obstruction as a result of a bleeding right renal angiomyolipoma (AML) with retroperitoneal hematoma. Her duodenal obstruction did not improve upon conservative management, and a computed tomography (CT)-guided drainage of the retroperitoneal hematoma was subsequently performed. Post-intervention, CT scan confirmed hematoma resolution, and she was able to resume normal diet afterwards. We present this first reported case of a bleeding renal AML with retroperitoneal hematoma causing duodenal obstruction and discuss on the management of such condition. 相似文献
997.
Background. Many patients with end-stage renal disease who are undergoing chronic hemodialysis suffer from sleep disturbance. This paper was designed to study the severity and prevalence of sleep disorders and the factors affecting the syndromes in this unique patient group. Methods. We conducted this study by the use of questionnaires. Included in this study were a total of 245 patients at our center who had end-stage renal disease (ESRD) and who received hemodialysis thrice weekly for more than three months. Their demographic data and biochemical and hematologic parameters were analyzed. All patients were asked to complete two questionnaires (in a Chinese version) of the Pittsburgh Sleep Quality Index (PSQI) and Beck Depression Inventory second edition (BDI-II), either by themselves or with assistance from the medical staff. Results. One hundred and sixty-four patients completed both questionnaires with a response rate of 70.4%. Their mean age was 57.9 ± 11.8 (ranging from 23.1 to 83.7) years old. They had been receiving hemodialysis for an average of 49.1 ± 50.9 months before the study. The male to female ratio was 77:87. Seventy six (46.3%) patients had diabetes mellitus. The prevalence of sleep disturbance was 74.4% (122/164), defined as PSQI scores >5. The poor sleepers had higher BDI scores and a higher ratio of females comparing to the good sleepers. By a multivariate analysis, the BDI scores and female sex were the independent predictors of the patients being poor sleepers. In analyzing the poor sleepers, the BDI scores, durations of hemodialysis and hemoglobin levels were the independent factors for predicting the global PSQI scores. Conclusion. The questionnaire showed a high prevalence of insomnia in the dialytic population. The study also attributes a predictive role in sleep quality to gender, depression, dialytic duration, and hemoglobin levels. The data indicate that in the management of insomnia in this patient group, anemia and depression, both of which are potentially correctable, should be assessed. 相似文献
998.
Yong Beom Kim Young Jin Chang Wol Seon Jung Sang Ho Byen Youn Yi Jo 《Journal of anesthesia》2013,27(6):827-831
Purpose
This prospective, randomized trial was designed to assess whether the i-gel supraglottic airway device is suitable for volume-controlled ventilation while applying positive end-expiratory pressure (PEEP) of 5 cmH2O under general anesthesia. It was believed that this device might improve arterial oxygenation.Methods
Forty adult patients (aged 20–60 years) scheduled for elective orthopedic surgery were enrolled in this study. Twenty patients were ventilated without external PEEP [zero positive end-expiratory pressure (ZEEP) group], and the other 20 were ventilated with PEEP 5 cmH2O (PEEP group) after placing an i-gel device. Volume-controlled ventilation at a tidal volume (TV) of 8 ml/kg of ideal body weight, leak volume, and arterial blood gas analysis were investigated.Results
The incidences of a significant leak were similar in the ZEEP and PEEP groups (3/20 and 1/20, respectively; P = 0.605), as were leak volumes. No significant PaO2 difference was observed between the two groups at 1 h after satisfactory i-gel insertion (215 ± 38 vs. 222 ± 54; P = 0.502).Conclusions
The use of an i-gel during PEEP application at 5 cmH2O did not increase the incidence of a significant air leak, and a PEEP of 5 cmH2O failed to improve arterial oxygenation during controlled ventilation in healthy adult patients. 相似文献999.
Se Jin Jung Soo-Jeong Cho Il Ju Choi Myeong-Cherl Kook Chan Gyoo Kim Jong Yeul Lee Sook Ryun Park Jun Ho Lee Keun Won Ryu Young-Woo Kim 《Surgical endoscopy》2013,27(4):1211-1218
Background and aims
The best therapeutic modality has not been established for gastric low-grade adenomas or dysplasia (LGD), which can progress to invasive carcinoma despite a low risk. This study aims to investigate the clinical efficacy, safety, and local recurrence after argon plasma coagulation (APC) treatment of gastric LGD compared with endoscopic submucosal dissection (ESD).Patients and methods
A total of 320 patients with gastric LGD ≤2.0 cm treated with APC or ESD between 2004 and 2011 were retrospectively analyzed. We compared local recurrence rate, complication rate, procedure time, and admission to hospital between APC and ESD groups.Results
Of the 320 patients, 116 patients were treated with APC and 204 with ESD. During follow-up, local recurrence was more common in the APC group (3.8 %, 4/106) than the ESD group (0.5 %, 1/188; log-rank test P = 0.036). However, all patients with local recurrence (n = 5) were treated by additional APC, and followed up without further recurrences. ESD was complicated by two perforations (1.0 %, 2/204) compared with no perforations in the APC group (0 %, 0/116). Bleeding complications were not different between the APC (1.7 %, 2/116) and ESD (2.0 %, 4/204) groups. Procedure time was shorter in the APC (7.8 ± 5.1 min) than the ESD (53.1 ± 38.1 min) group (P < 0.001). The proportion of hospitalization was less in the APC group (31.0 %, 36/116) than the ESD group (100.0 %, 204/204) (P < 0.001).Conclusions
APC can be a good treatment option for patients with LGD ≤2.0 cm. 相似文献1000.
Ji Yong Ahn Hwoon-Yong Jung Sue Eun Bae Ji Hoon Jung Ji Young Choi Mi-Young Kim Jeong Hoon Lee Kwi-Sook Choi Do Hoon Kim Kee Don Choi Ho June Song Gin Hyug Lee Jin-Ho Kim Seungbong Han 《Surgical endoscopy》2013,27(3):910-917