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81.
目的 观察曲马多防治硬膜外麻醉期间寒战反应时两种用药方法的临床效果。 方法硬膜外麻醉手术期间发生寒战的 6 0例成年患者 ,当出现寒战分级达 2~ 3级时 ,用室温下盐酸曲马多 1mg kg加氟哌啶 2 .5mg缓慢静脉推注 ,随机分成二组 :研究组 (R组 )与对照组 (C组 ) ,每组各 30例 ;R组在 5min内用上述同样药物和剂量予以肌内注射 ,C组以生理盐水 2ml肌内注射。观察寒战的治疗效果及 6h内寒战复发率。 结果 两组均于静注曲马多后 3min内起效 ,所有病人寒战反应均得到缓解 ,6h内R组均无寒战反应复发 ,C组有 5例再次出现寒战达 2级以上 ,给予追加首次量的 1 2后缓解 ,两组间差异有显著性 (P <0 .0 5 )。 结论 静注加肌注曲马多和氟哌啶可更有效地防治硬膜外麻醉期间的寒战反应。 相似文献
82.
目的 探讨自发性颈动脉海绵窦瘘的诊治方法。方法 9例单纯颈内动脉供血,其中6例采取球囊瘘内闭塞术,3例采用瘘口一同闭塞的颈内动脉闭塞术。11例采用微导管超选择性插管,行瘘的供血动脉及瘘口栓塞。栓塞后7例仍有供血者3例经压颈1个月瘘口消失,2例疗效不满意,患者未再来治疗,2例采取经岩下窦途径和经眼静脉途径。1例单纯由颈内动脉脑膜支供血的行γ刀治疗。结果 13例栓塞后造影瘘口完全闭塞,7例栓塞后造影瘘口有显影,术后采取压迫患侧颈总动脉1个月,半年后3例造影瘘口消失,2例疗效不满意,失去随访,2例经眼静脉、岩下窦栓塞海绵窦取得成功。γ刀治疗1例,症状消失。19例随访6个月未见瘘口再通。结论 介入栓塞是治疗自发性颈动脉海绵窦瘘行之有效的方法。 相似文献
83.
地塞米松缓释微粒在增生性玻璃体视网膜病变的应用 总被引:2,自引:0,他引:2
目的:观察含地塞米松(DEX)的缓释微粒治疗增生性玻璃体视网膜病变(PVR)的临床疗效。方法:9例(9只眼)视网膜脱离伴PVR患者进行常规玻璃体视网膜手术,并在玻璃体腔内植入1粒DEX微粒(含地塞米松1mg),观察术后反应及视力、PVR发展、DEX的位置及形状变化等。结果:术后炎症反应轻,7只眼视网膜复位,3只眼后极部视网膜前有增生;2只眼视网膜局限性脱离,最终3只眼玻璃腔内硅油填充。随访视力有8只眼较术前提高(P=0.015)。DEX未见对视网膜有不良影响,仅在随着处有少量色素吸附,4-6月后吸收。结论:DEX抑制PVR术后炎症反应及较远期作用是安全、有效的;对手术未完全清除的视网膜前增生有一定的抑制作用。 相似文献
84.
关于课堂多媒体教学的思考 总被引:10,自引:1,他引:9
多媒体教学已成为课堂教学的一种常用手段,多媒体教学应从实际需要出发,以提高教学效果为目标;需要教师掌握多种计算机及多媒体知识技能,科学地进行教学设计;教学过程中应发挥多媒体的优势,注重师生交流。对此本文进行了探讨。 相似文献
85.
LaVoie Edmond J.; Cai Zhen-Wei; Meschter Carol L.; Weyand Eric H. 《Carcinogenesis》1994,15(10):2131-2135
Fluoranthene (FA) is frequently among the more abundant componentsdetected in environmental mixtures of polycyclic aromatic hydrocarbons.Several methylated fluoranthenes, although less prevalent thanFA, have also been detected as environmental pollutants. WhileFA is inactive as a tumorigenic agent on mouse skin, it doesinduce lung and liver tumors in newborn mice. Among the fiveisomers of methylfluoranthene, only 2-methylfluoranthene (2-MeFA)and 3-methylfluoranthene (3-MeFA) are active as tumor initiatorson mouse skin. A comparative bioassay was performed to determinethe relative tumorigenic activity of FA, 2-MeFA and 3-MeFA innewborn CD-1 mice. All three compounds were assayed at dosesof 3.46 and 17.3 µmol. The bioassay was terminated whenmice were 1 year old. At a dose of 17.3 µmol, FA and 2-MeFAinduced a similar incidence of lung tumors (6596%) inboth male and female mice. However, tumor multiplicity in thelung was different between FA and 2-MeFA. At a dose of 17.3µmol, the multiplicity of lung tumors observed for miceadministered 2-MeFA ranged from 3.04 to 3.94 tumors per mouse.In contrast, animals treated with FA developed only an averageof 1.122.45 tumors per mouse. 3-MeFA did not induce astatistically significant incidence of lung tumors in eithermale or female mice. All three compounds when administered tonewborn mice did induce a significant incidence of liver tumorsamong male mice. The relative tumorigenic potency observed wasFA 5 相似文献
86.
Zhi-gang Wang Yi-dong Huang Ke-luo Cheng Xiao-bi Cai Zheng Wu Jian-dong Zhan 《第一军医大学学报》2004,24(3):345-6, 351
OBJECTIVE: To study how blood supply of the esophageal and gastric stumps influences the anastomotic healing after esophagogastrostomy in rabbits. METHODS: Twenty-seven New Zealand rabbits were randomly divided into 3 groups to receive esophagogastrostomy, followed by different procedures. Except for those in group I, all the rabbits were subjected to procedures of reducing the blood supply either of the esophageal or the gastric stump (group II and group III, respectively), followed by single-layer esophagogastric anastomoses using interrupted 5-0 polypropylene sutures. Ten days after operation, all the rats were killed and the anastomotic sites excised for measurement of the inner diameter, tensile strength, and hydroxyproline concentration. RESULTS: Healing of the esophagograstric anastomosis was obtained in all the rabbits but one with anastomotic leakage in group I and one with perforation of the gastric fundus in group III. The anastomotic inner diameters were similar in all the three groups, whereas the tensile strength and hydroxyproline concentration at the anastomoses decreased in group III in comparison with the other two groups (P<0.05) that had similar measurements (P>0.05). CONCLUSIONS: Extended length of the free esophageal stump does not significantly affect anastomotic healing as decrease of blood supply in the gastric stump. 相似文献
87.
The effect of vascular endothelial growth factor on the healing of ischaemic skin wounds. 总被引:7,自引:0,他引:7
F Zhang M P Lei T M Oswald Y Pang B Blain Z W Cai W C Lineaweaver 《British journal of plastic surgery》2003,56(4):334-341
The effect of exogenous vascular endothelium growth factor (VEGF) on wound healing in an ischaemic skin flap model was evaluated in this study. Seventy-two Sprague-Dawley rats were used. Normal incisional wound and H-shaped double flaps were used as the wound models. The study was divided into two parts. In Part I, VEGF protein levels were determined from the incisional and H-shaped ischaemic wounds at 12 and 24 h, postoperatively. In Part II, tensile strength and immunohistochemical stains were examined to determine the level of microvessel density (MVD) at 1 and 2 weeks, postoperatively in simple incisional wounds, ischaemic wounds, and ischaemic wounds following 1 ml (1 microg/ml) exogenous VEGF injections into the subcutaneous tissue. The results showed a significantly higher level of VEGF protein in the ischaemic wounds than the incisional wounds. Tensile strength was statistically higher in the incisional wound group and in the ischaemic flap wounds with VEGF treatment compared to the ischaemic flaps with no treatment at 1 week, postoperatively (p>0.05). MVD data indicated that ischaemic wound repair with VEGF treatment had significantly higher MVD than the normal incisional wounds and ischaemic wounds without treatment. We conclude that exogenous application of VEGF can increase early angiogenesis and tensile strength in the ischaemic wound. 相似文献
88.
Abstract – Dental injuries are common following facial trauma. This article presents a rare injury: the dislocation of a third molar into the maxillary sinus after complex mandibular and maxillary tuberosity fractures. The possible mechanism and clinical treatment are discussed. 相似文献
89.
90.
本文报告不同种的金银花中微量生物元素的分布规律:不同种的金银花中微量生物元素含量的对数与其元素的原子序数成线性关系,并呈现周期性。 相似文献