全文获取类型
收费全文 | 1764篇 |
免费 | 107篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 60篇 |
儿科学 | 52篇 |
妇产科学 | 41篇 |
基础医学 | 239篇 |
口腔科学 | 23篇 |
临床医学 | 108篇 |
内科学 | 481篇 |
皮肤病学 | 42篇 |
神经病学 | 120篇 |
特种医学 | 41篇 |
外科学 | 212篇 |
综合类 | 10篇 |
预防医学 | 151篇 |
眼科学 | 69篇 |
药学 | 89篇 |
中国医学 | 7篇 |
肿瘤学 | 128篇 |
出版年
2023年 | 7篇 |
2022年 | 14篇 |
2021年 | 45篇 |
2020年 | 20篇 |
2019年 | 52篇 |
2018年 | 46篇 |
2017年 | 43篇 |
2016年 | 35篇 |
2015年 | 34篇 |
2014年 | 55篇 |
2013年 | 84篇 |
2012年 | 103篇 |
2011年 | 105篇 |
2010年 | 59篇 |
2009年 | 60篇 |
2008年 | 90篇 |
2007年 | 98篇 |
2006年 | 94篇 |
2005年 | 98篇 |
2004年 | 91篇 |
2003年 | 98篇 |
2002年 | 74篇 |
2001年 | 77篇 |
2000年 | 91篇 |
1999年 | 67篇 |
1998年 | 18篇 |
1997年 | 13篇 |
1996年 | 9篇 |
1995年 | 6篇 |
1994年 | 9篇 |
1993年 | 5篇 |
1992年 | 22篇 |
1991年 | 18篇 |
1990年 | 10篇 |
1989年 | 14篇 |
1988年 | 19篇 |
1987年 | 14篇 |
1986年 | 18篇 |
1985年 | 11篇 |
1984年 | 5篇 |
1983年 | 4篇 |
1979年 | 4篇 |
1977年 | 4篇 |
1975年 | 2篇 |
1974年 | 4篇 |
1973年 | 3篇 |
1970年 | 3篇 |
1969年 | 3篇 |
1968年 | 2篇 |
1965年 | 2篇 |
排序方式: 共有1873条查询结果,搜索用时 15 毫秒
81.
Henrique Caballero STEINHAUSER Cecília Pedroso TURSSI Fabiana Mantovani Gomes FRAN?A Flávia Lucisano Botelho do AMARAL Roberta Tarkany BASTING 《Journal of applied oral science : revista FOB》2014,22(2):85-90
Objective
The aim of this study was to evaluate the effect of feldspathic ceramic surface cleaning on micro-shear bond strength and ceramic surface morphology.Material and Methods
Forty discs of feldspathic ceramic were prepared and etched with 10% hydrofluoric acid for 2 minutes. The discs were randomly distributed into five groups (n=8): C: no treatment, S: water spray + air drying for 1 minute, US: immersion in ultrasonic bath for 5 minutes, F: etching with 37% phosphoric acid for 1 minute, followed by 1-minute rinse, F+US: etching with 37% phosphoric acid for 1 minute, 1-minute rinse and ultrasonic bath for 5 minutes. Composite cylinders were bonded to the discs following application of silane and hydrophobic adhesive for micro-shear bond strength testing in a universal testing machine at 0.5 mm/min crosshead speed until failure. Stereomicroscopy was used to classify failure type. Surface micromorphology of each treatment type was evaluated by scanning electron microscopy at 500 and 2,500 times magnification.Results
One-way ANOVA test showed no significant difference between treatments (p=0.3197) and the most common failure types were cohesive resin cohesion followed by adhesive failure. Micro-shear bond strength of the feldspathic ceramic substrate to the adhesive system was not influenced by the different surface cleaning techniques. Absence of or less residue was observed after etching with hydrofluoric acid for the groups US and F+US.Conclusions
Combining ceramic cleaning techniques with hydrofluoric acid etching did not affect ceramic bond strength, whereas, when cleaning was associated with ultrasound, less residue was observed. 相似文献82.
83.
Wilberg A. Moncada Arita Eduardo Smelin Perdomo Domínguez Astrid Yohaly Rivera Caballero Nelson A. EspinozaMoreno Mauricio E. Zavala Galeano Barbara R. DuPont Hctor M. RamosZaldívar 《Clinical Case Reports》2022,10(4)
Less than one percent of individuals with Down syndrome exhibit mosaicism, a biological phenomenon that describes an individual who has two or more genetically distinct cell lines. The percentage of mosaicism in different tissues can impact the presence of clinical findings and hinder cytogenetic diagnosis. We report a case of mosaicism for trisomy 21 diagnosed after multi‐tissue cytogenetic analysis of peripheral blood and buccal mucosa, associated with significant intellectual disability, dysmorphic facial features, congenital heart defects, macropenis, and imperforate anus. 相似文献
84.
85.
The Icatibant Outcome Survey: experience of hereditary angioedema management from six European countries
下载免费PDF全文
![点击此处可从《Journal of the European Academy of Dermatology and Venereology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
86.
Caballero Giné JM Borrat Font P Martí Picas L Ristol Pont J 《Actas urologicas espa?olas》2000,24(5):413-415
Two cases of amyloidosis of the bladder are reported: 1) a 45 year old man with haematuria. Cystoscopic examination reveals several tumours in the wall of the bladder. Transuretral resection was performed and histopathological examination revealed primary amyloidosis. Systemic amyloidosis was excluded. He was treated with oral colchicine with success. 2) a 71 year old male with diagnosis of rheumatoid arthritis and systemic amyloidosis visited our hospital with massive haematuria. Transuretral resection was unsuccessful and was necessary surgical ligation of hypogastric arteries. 相似文献
87.
Ximena Calderón‐Castrat M.D. Rosa Castro M.D. Johanna Peceros‐Escalante M.D. Marjorie Villate Caballero M.D. Cesar Chian M.D. Rosalía Ballona M.D. 《Pediatric dermatology》2017,34(3):e109-e115
Pediatric Degos disease is rare, with only 36 cases reported in the medical literature. Classically the diagnosis has been established according to pathognomonic histopathologic findings, but when these features are not present, there may be a delay in diagnosis. We report the second congenital case of Degos disease, highlighting the clinical and dermoscopic findings. 相似文献
88.
Marcos Rossi Izquierdo Andrés Soto Varela Sofía Santos Pérez Torcuato Labella Caballero 《Acta otorrinolaringologica espanola》2009,60(4):234-237
IntroductionThe aim of this study was to determine the prevalence of benign paroxysmal positional vertigo (BPPV) in patients diagnosed with endolymphatic hydrops (EH) and to analyze whether this association is a factor for poor prognosis in these patients.Material and methodsA retrospective study was carried out in our department among the patients definitively diagnosed as having Ménière's disease according to the criteria of the American Academy of Otolaryngology and BPPV by the usual triggering manoeuvres.ResultsThe prevalence of BPPV in our patients with EH was 5.1%. The rate of cure with the repositioning manoeuvres is 90.9%, however success with the first manoeuvre was only 63.36%. Recurrences occurred in up to 22.22%. We found a lower success rate with the first manoeuvre in relation to the rest of the patients with BPPV without EH. This difference is statistically significant (P=0.042).DiscussionWe did not find that these patients to have a lower rate of cure with the repositioning manoeuvres or a higher rate of recurrence. But in our protocol the first manoeuvre had a lower success rate than in the rest of the patients. 相似文献
89.
Fernando Caballero Martínez Vicente Plaza Santiago Quirce Gancedo Margarita Fernández Benítez Fernando Gómez Ruiz Antolín López Viña Jesús Molina París José Antonio Quintano Jiménez Ramona Soler Vilarrasa José Ramón Villa Asensi Santiago Balmes Estrada 《Archivos de bronconeumologia》2010,46(8):411-419
ObjectivesTo assess the level of agreement on the GEMA 2009 clinical recommendations by a Spanish expert panel on asthma.Materials and methodsThe study was divided into four stages: 1) establishment of a 9 member scientific committee (GEMA authors) for selection of GEMA recommendations to use in the survey; 2) formation of a panel of 74 professionals with expertise in this field (pulmonologists, allergists, family doctors, ear, nose and throat and paediatric specialists); 3) Delphi survey in two rounds, sent by mail, with intermediate processing of opinions and a report to the panel members; and 4) analysis and discussion of results for the Scientific Committee.ResultsSeventy four participants completed the two rounds of survey. During the first round, a consensus was reached in 49 out of 56 questions analysed. Following discussion by the panel, the consensus was increased to a total of 53 items in the survey. With respect to the remaining questions, Insufficient consensus was obtained on the rest of the questions, due to differing views between sub-specialists, or lack of criteria by most of the experts.ConclusionsThe external analysis by asthma experts from different specialities showed a high level of professional agreement with the GEMA 2009 recommendations in Spain (96.5 %). The disagreement shown in three recommendations reflect the lack of a high level evidence. These issues represent areas of interest for future research. 相似文献
90.
Carlos Camps Cristina Caballero Rafael Sirera Ana Blasco Diego Cayuela Mireia Gil Xavier Badía 《Clinical & translational oncology》2008,10(2):96-101
Cancer is a high incidence disease, forcing healthcare systems to assign a significant amount of resources to its treatment. New developments have arisen recently: development of new agents that act at specific steps of cellular differentiation and proliferation and identification of predictive genetic markers which allow sub-groups of patients that will benefit from these agents, alone or in combination with chemotherapy, to be targeted. The majority of new drugs coming to the market combine greater clinical benefit and higher costs. Constraints on healthcare budgets worldwide make it necessary to rationalise the expense by prioritising allocation of available resources to the most efficient interventions, so that the best possible clinical result can be obtained at a reasonable cost and with the best quality of life for the patient. Economic evaluation studies represent the only tool available to scientifically determine the cost-effectiveness of new treatments and the budgetary impact of their introduction to the therapeutic arsenal available for the treatment of cancer. 相似文献