全文获取类型
收费全文 | 1288篇 |
免费 | 79篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 8篇 |
儿科学 | 71篇 |
妇产科学 | 12篇 |
基础医学 | 146篇 |
口腔科学 | 60篇 |
临床医学 | 78篇 |
内科学 | 226篇 |
皮肤病学 | 13篇 |
神经病学 | 109篇 |
特种医学 | 119篇 |
外国民族医学 | 2篇 |
外科学 | 152篇 |
综合类 | 62篇 |
预防医学 | 40篇 |
眼科学 | 78篇 |
药学 | 92篇 |
中国医学 | 1篇 |
肿瘤学 | 106篇 |
出版年
2022年 | 18篇 |
2021年 | 21篇 |
2020年 | 16篇 |
2019年 | 21篇 |
2018年 | 25篇 |
2017年 | 18篇 |
2016年 | 29篇 |
2015年 | 37篇 |
2014年 | 31篇 |
2013年 | 43篇 |
2012年 | 52篇 |
2011年 | 65篇 |
2010年 | 43篇 |
2009年 | 35篇 |
2008年 | 61篇 |
2007年 | 59篇 |
2006年 | 59篇 |
2005年 | 58篇 |
2004年 | 43篇 |
2003年 | 37篇 |
2002年 | 56篇 |
2001年 | 56篇 |
2000年 | 39篇 |
1999年 | 43篇 |
1998年 | 41篇 |
1997年 | 32篇 |
1996年 | 22篇 |
1995年 | 28篇 |
1994年 | 24篇 |
1993年 | 11篇 |
1992年 | 18篇 |
1991年 | 10篇 |
1990年 | 10篇 |
1989年 | 28篇 |
1988年 | 19篇 |
1987年 | 27篇 |
1986年 | 18篇 |
1985年 | 16篇 |
1984年 | 7篇 |
1983年 | 8篇 |
1982年 | 9篇 |
1981年 | 10篇 |
1980年 | 9篇 |
1977年 | 4篇 |
1975年 | 8篇 |
1974年 | 4篇 |
1972年 | 5篇 |
1971年 | 9篇 |
1969年 | 4篇 |
1966年 | 8篇 |
排序方式: 共有1375条查询结果,搜索用时 15 毫秒
91.
92.
Kapoula Z Bucci MP Bernotas M Zamfirescu F 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》2000,131(4):500-510
Binocular saccades in response to briefly flashed, memorized disparate targets (different for the two eyes) become disconjugate following repeated trials. After 15 min of such training, the disconjugacy persists, even when the target to memorize is no longer disparate. This study examines the hypothesis that disparity memorization has a motor basis. We report here three experiments in which subjects were trained for 15-min periods. In experiment 1, subjects made no saccade after target presentation (static training); in experiment 2 subjects intended to make a saccade, but they actually made a saccade in only 10% or 20% of the trials; in experiment 3 subjects made anti-saccades. For all three experiments, the flashed target was disparate and the memory delay for each trial was 1 s. To examine the effects of learning for all three experiments, before and after training, we recorded memory-guided saccades to non-disparate targets (monocular viewing). Experiments 1 and 2 produced inconsistent (before/after training) changes in the disconjugacy of saccades. Thus, the disparity of potential saccade targets had no lasting effect on the disconjugacy of saccades if a saccade was not made. In contrast, the anti-saccades in experiment 3 developed a disconjugacy opposite to the disparity of the remembered target. These findings indicate that the execution of the saccade is necessary to memorize disparity of the target. 相似文献
93.
Alveolar capillary dysplasia. Report of a case of prolonged life without extracorporeal membrane oxygenation (ECMO) and review of the literature 总被引:3,自引:0,他引:3
Al-Hathlol K Phillips S MK Seshia Casiro O Alvaro RE Rigatto H 《Early human development》2000,57(2):85-94
We describe an unusual infant with the diagnosis of alveolar capillary dysplasia who had a relatively prolonged life without extracorporeal membrane oxygenation (ECMO). We have used this case as a springboard for a thorough review of the literature. This was a full-term female infant who presented with a picture of persistent pulmonary hypertension of the newborn. She was treated as such, with various ventilatory modes, alkalinizing agents, surfactant therapy, tolazoline, prostacyclin and nitric oxide. Because of the prolonged clinical course the possibility of alveolar capillary dysplasia was raised. The parents refused ECMO. Despite all efforts she progressively deteriorated and died at 22 days of age. Macro- and microscopic examination of the lung at autopsy were diagnostic of alveolar capillary dysplasia. A detailed review of 39 cases published in the literature with comments regarding incidence, etiology, pathophysiology, clinical picture, diagnosis and treatment is presented. 相似文献
94.
95.
G Bucci 《Minerva pediatrica》1973,25(36):1516-1526
96.
Moretti C Gizzi C Papoff P Lampariello S Capoferri M Calcagnini G Bucci G 《Early human development》1999,56(2-3):167-177
In this study we hypothesized that nasal synchronized intermittent positive pressure ventilation (nSIPPV) would provide more ventilatory support than nasal continuous positive airway pressure (nCPAP) in the immediate post-extubation period in very low birth weight (VLBW) infants. We tested this hypothesis by comparing the effects of these two ventilatory techniques on ventilation, gas exchange, and patient inspiratory effort in 11 preterm infants immediately after extubation. All neonates studied (BW: 1141+/-(SEM) 53 g; GA: 28.1+/-(SEM) 0.5 wks) had received mechanical ventilation because of respiratory distress at birth and were extubated by day 14 of life. Nasal SIPPV and nCPAP were applied in random order to each infant after extubation so that each was his/her own control. Both nCPAP and nSIPPV were delivered at end-expiratory pressures (PEEP) of 3 cm H2O. Inspiratory times (Ti) and peak inspiratory pressures set during nSIPPV were the same as those used at the time of extubation. Recordings lasted 45 min in each mode of ventilation. Tidal volume (Vt), minute volume (Ve), respiratory rate (RR), airway pressure (Paw), transcutaneous PO2 (TcPO2) and PCO2 (TcPCO2) as well as phasic esophageal pressure deflections (Pe), as an estimate of inspiratory effort, were measured. The measurements obtained during both modes of ventilation indicated significant differences between the two techniques. Indeed, application of nSIPPV was associated with a statistically significant increase in Vt and Ve. In addition, Pe decreased by 30% during nSIPPV (P<0.01). TcPCO2 was statistically significantly lower during nSIPPV than nCPAP, and RR as well. These data therefore suggest that nSIPPV may provide more ventilatory support than nCPAP in the post-extubation period with less patient inspiratory effort. 相似文献
97.
R Bahl N Bhandari MK Bhan M Saxena A Bagati 《Acta paediatrica (Oslo, Norway : 1992)》1996,85(11):1290-1294
Objectives : To determine the efficacy of antimicrobial treatment in non-dysenteric persistent diarrhoea in a community setting. Methods : In this double-blind field trial, 156 children aged 4 36 months with persistent diarrhoea not associated with Giardia lamblia infestation seeking treatment in a community outpatient clinic, were randomized to receive a combination of nalidixic acid and metronidazole, metronidazole alone, or placebo for 7 days. Results : In comparison with placebo, metronidazole treatment did not result in a significant reduction in the mean post-enrolment diarrhoeal duration and stool frequency, increase in the proportion of patients recovered by days 3, 5 and 7 of treatment, and increase in weight gain at days 7 and 14. Comparing the combination of nalidixic acid and metronidazole with metronidazole alone, 17.5% more children treated with the combination recovered by day 3 of treatment ( p = 0.08) and the mean stool frequency ascertained on day 7 for the previous 24 h was 26.8% less in them ( p = 0.05). The weight gains at days 7 and 14 were similar in the two groups. Conclusions : These findings indicate that metronidazole offers no therapeutic benefit in persistent diarrhoea not associated with Giardia lamblia and nalidixic acid has only a modest clinical benefit, which is not substantial enough to warrant its routine use. 相似文献
98.
The adsorption of quinidine onto kaolin was studied as a function of pH in aqueous solutions in which the ionic strength was adjusted to 0.1. The interaction of quinidine with pectin also was investigated in water and in phosphate buffer; the buffer pH and ionic strength were adjusted to 6.5 and 0.1, respectively. The in vitro results indicated that quinidine was adsorbed onto kaolin. At the highest concentration studied, the extent of adsorption increased from 3.64 mg of quinidine adsorbed/g of adsorbent at pH 2.4 to an average of 5.81 mg/g in the pH 5.5-7.5 range. In the presence of electrolytes, the interaction of quinidine with pectin was relatively small (3-13% bound) as compared to studies performed in water (66-90% bound). The data indicate that some quinidine may be adsorbed when this drug is administered concurrently with kaolin-pectin preparations. 相似文献
99.
100.