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81.
U PODDAR Y CHAWLA RK DHIMAN K VAIPHEI RK VASISHTA JB DILAWARI 《Journal of gastroenterology and hepatology》1998,13(1):109-111
Ascites may be associated with fulminant hepatic failure (FHF), but spontaneous bacterial peritonitis (SBP) is an extremely rare complication. We report on two patients with FHF who developed SBP. One patient died and the other recovered. 相似文献
82.
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In vitro and in vivo selectin-blocking activities of sulfated lipids and sulfated sialyl compounds 总被引:2,自引:0,他引:2
Mulligan MS; Warner RL; Lowe JB; Smith PL; Suzuki Y; Miyasaka M; Yamaguchi S; Ohta Y; Tsukada Y; Kiso M; Hasegawa A; Ward PA 《International immunology》1998,10(5):569-575
There is accumulating evidence that sulfated lipids, sulfated
oligosaccharides and other sulfated compounds are reactive with selectins
in a manner that interferes with selectin interactions with their natural
ligands. In the report we describe the ability of sulfated lipids
(sulfatides and gangliosides) and multimeric forms of sulfated sialic acid
to block binding of P- and E-selectin-Ig to neutrophils. The in vivo
ability of these compounds to block lung injury in rats following i.v.
infusion of purified cobra venom factor (CVF), which induces injury that is
L- and P-selectin dependent, was also determined as well as effects on
recruitment of neutrophils, as measured by lung myeloperoxidase. There was
a significant correlation between the ability of sulfated lipids and sialyl
compounds to interfere in vitro with P-selectin-Ig binding to neutrophils
and to protect against P-selectin-dependent acute lung injury induced by
CVF. The biological effects of these sulfated compounds were also
associated with diminished accumulation of neutrophils. The protective
effects of these compounds may be linked to their ability to interfere with
P- selectin binding to counter-receptors on neutrophils.
相似文献
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86.
Kalman滤波分光光度法同时测定多相脂质体口服液中氟尿嘧啶和尼泊金的含量 总被引:1,自引:0,他引:1
本文提出了对测量值平滑后,用Kalman滤波分光光度法同时测定多相脂质体口服液中氟尿嘧啶和尼泊金的含量,改善了滤波效果,较好地解决了复杂基质存在下多组分的同时测定。用人工合成样考察表明,在269~273nm间滤波结果较好。用分别相当制剂标示量80,100,120%的两组分九种可能组合人工合成样品考查结果表明,氟尿嘧啶和尼泊金的回收率分别为99.3~102.6%和97.8~103.0%;当存在系统误差时,回收率分别为99.4~102.7%和97.0~102.9% 相似文献
87.
88.
肺移植后肺感染的发生率比其它器官移植后明显增高,这提示移植肺的免疫反应可能受损。为了研究肺淋巴引流中断对抗体反应的影响,我们用肺门剥脱鼠作为模型,设计了3个实验:(1)用着色淋巴造影术目视检查肺门淋巴管的再生;(2)在支气管内滴注碳粒子后观察粒子从肺到肺引流淋巴结的运输;(3)用羊红细胞使肺免疫后测定抗体反应。结果显示肺门淋巴管被肺门剥脱术所中断,在术后7天开始再生;在术后第1周粒子运输到肺引流淋巴结受阻,此后逐渐恢复正常;在肺门剥脱后7天和10天免疫的鼠血清抗体反应缺如或低下,其后1月内恢复。由此得出结论,只要抗原不能经淋巴管从肺运送到肺引流淋巴结,肺门剥脱肺内的抗原抗体反应就受到损害。该发现可部分地解释为什么在肺移植后最初几周内经常发生肺感染。 相似文献
89.
OBJECTIVES: We aim to introduce Piaget's concept of 'operational knowledge'
from the cognitive theory of learning--as a contribution to the broader
understanding of clinical interaction. METHOD: Our study involves a
theoretical presentation of different kinds and levels of human
understanding, illustrated by a case story in which the difference between
operational and figurative knowledge was demonstrated. This study used the
case story of a male patient aged 80, who was suffering from ulcerative
colitis. We appealed to the reader's perceived relevance of these
perspectives, in order to understand what was going on between doctor and
patient. RESULTS: The case story demonstrates the phenomenon of operational
knowledge in the patient, the close links between communicative action and
cognitive understanding, and the importance for the doctor of reflecting
upon this level of interaction. CONCLUSION: According to the
patient-centred clinical method, the doctor should explore the social and
emotional context of the patient in order to understand the meaning of the
illness. We suggest that a cognitive dimension should also be added, and
that the concept of 'operational knowledge' might be useful for such
investigations.
相似文献
90.