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991.
Christopher M. Ireland Randy O. Giaquinto Wolfgang Loew Jean A. Tkach Ronald G. Pratt Beth M. Kline‐Fath Stephanie L. Merhar Charles L. Dumoulin 《Concepts in magnetic resonance. Part B, Magnetic resonance engineering.》2015,45(3):107-114
Magnetic resonance imaging (MRI) acoustic exposure has the potential to elicit physiological distress and impact development in preterm and term infants. To mitigate this risk, a novel acoustically quiet coil was developed to reduce the sound pressure level experienced by neonates during MR procedures. The new coil has a conventional high‐pass birdcage radio frequency design, but is built on a framework of sound abating material. We evaluated the acoustic and MR imaging performance of the quiet coil and a conventional body coil on two small footprint neonatal intensive care unit MRI systems. Sound pressure level and frequency response measurements were made for six standard clinical MR imaging protocols. The average sound pressure level, reported for all six imaging pulse sequences, was 82.2 dBA for the acoustically quiet coil, and 91.1 dBA for the conventional body coil. The sound pressure level values measured for the acoustically quiet coil were consistently lower, 9 dBA (range 6–10 dBA) quieter on average. The acoustic frequency response of the two coils showed a similar harmonic profile for all imaging sequences. However, the amplitude was lower for the quiet coil, by as much as 20 dBA. © 2015 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 45B: 107–114, 2015 相似文献
992.
Neoadjuvant gemcitabine,docetaxel, and capecitabine followed by gemcitabine and capecitabine/radiation therapy and surgery in locally advanced,unresectable pancreatic adenocarcinoma 下载免费PDF全文
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NRG Oncology/RTOG 0921: A phase 2 study of postoperative intensity‐modulated radiotherapy with concurrent cisplatin and bevacizumab followed by carboplatin and paclitaxel for patients with endometrial cancer 下载免费PDF全文
Akila N. Viswanathan MD MPH Jennifer Moughan MS Brigitte E. Miller MD Ying Xiao PhD Anuja Jhingran MD Lorraine Portelance MD Walter R. Bosch DSc Ursula A. Matulonis MD Neil S. Horowitz MD Robert S. Mannel MD Luis Souhami MD Beth A. Erickson MD Kathryn A. Winter MS William Small MD Jr David K. Gaffney MD PhD 《Cancer》2015,121(13):2156-2163
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Intentions for risk‐reducing surgery among high‐risk women referred for BRCA1/BRCA2 genetic counseling 下载免费PDF全文
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Factors influencing ovulation and the risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers 下载免费PDF全文
Joanne Kotsopoulos Jan Lubinski Jacek Gronwald Cezary Cybulski Rochelle Demsky Susan L. Neuhausen Charmaine Kim‐Sing Nadine Tung Susan Friedman Leigha Senter Jeffrey Weitzel Beth Karlan Pal Moller Ping Sun Steven A. Narod 《International journal of cancer. Journal international du cancer》2015,137(5):1136-1146
The role of the lifetime number of ovulatory cycles has not been evaluated in the context of BRCA‐associated ovarian cancer. Thus, we conducted a matched case–control study to evaluate the relationship between the cumulative number of ovulatory cycles (and contributing components) and risk of developing ovarian cancer in BRCA mutation carriers (1,329 cases and 5,267 controls). Information regarding reproductive and hormonal factors was collected from a routinely administered questionnaire. Conditional logistic regression was used to evaluate all associations. We observed a 45% reduction in the risk of developing ovarian cancer among women in the lowest vs. highest quartile of ovulatory cycles (OR = 0.55; 95% CI 0.41–0.75, p = 0.0001). Breastfeeding for more than 12 months was associated with a 38% (95% CI 0.48–0.79) and 50% (95% CI 0.29–0.84) reduction in risk among BRCA1 and BRCA2 mutation carriers, respectively. For oral contraceptive use, maximum benefit was seen with five or more years of use among BRCA1 mutation carriers (OR = 0.50; 95% CI 0.40–0.63) and three or more years for BRCA2 mutation carriers (OR = 0.42; 95% CI 0.22–0.83). Increasing parity was associated with a significant inverse trend among BRCA1 (OR = 0.87; 95% CI 0.79–0.96; p‐trend = 0.005) but not BRCA2 mutation carriers (OR 0.98; 95% CI 0.81–1.19; p‐trend = 0.85). A later age at menopause was associated with an increased risk in women with a BRCA1 mutation (OR trend = 1.18; 95% CI 1.03–1.35; p = 0.02). These findings support an important role of breastfeeding and oral contraceptive use for the primary prevention of ovarian cancer among women carrying BRCA mutations. 相似文献
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999.
Unick JL Bond DS Jakicic JM Vithiananthan S Ryder BA Roye GD Pohl D Trautvetter J Wing RR 《Obesity surgery》2012,22(3):347-352
Background
Objective quantification of physical activity (PA) is needed to understand PA and sedentary behaviors in bariatric surgery patients, yet it is unclear whether PA estimates produced by different monitors are comparable and can be interpreted similarly across studies. 相似文献1000.