Intraoperative radiotherapy of breast cancer

In the systemic therapy of breast cancer, the tumor itself has become the specific target. If possible the surgical excision of breast carcinoma is restricted to the tumor site and aims at an R0 resection of the invasive and preinvasive portions of the carcinoma. Only percutaneous whole-breast radiotherapy irradiates the whole breast. The additional boost irradiation is targeted and significantly improves local control in all age groups. Due to the increased detection of small breast carcinomas in postmenopausal patients by mammographic screening, it is necessary to consider a change of the existing therapeutic practice. Published results of partial irradiation of the breast (intra- as well as postoperatively) show a very high degree of local control with follow-ups of up to 11 years. At present prospective and randomized studies investigate for which patients an intraoperative radiotherapy is sufficient as the sole irradiation method after previous surgery. Intraoperative radiotherapy as a boost preceding percutaneous whole-breast irradiation should already be possible according to a relevant statement of the DEGRO.     

Multiple pregnancies

Twin and multiple pregnancies carry an increased risk compared to singleton pregnancies and a challenge in obstetrical management. Multiple births are a worldwide issue, especially due to the increased incidence in several countries in the last few years. Prenatal care and obstetrical management call for specific solutions due to specific risks in such pregnancies. The present papers try to give both an overview and to offer a deeper insight into selected problems of obstetrical care for multiple pregnancies.     

Paratyphus-B-Meningitis bei Einem Säugling

Ohne Zusammenfassung     

Buchbesprechungen

Ohne Zusammenfassung     

über Störungen im Kohlehydratstoffwechsel beim Morbus Basedow

Ohne Zusammenfassung     

Folliculin

Ohne Zusammenfassung     

Hypophysenvorderlappenhormon und Ovarialhormon im Harn von Schwangeren

Ohne ZusammenfassungVorgetragen von Aschheim auf d. Gynäkologen-Kongre\ in Bonn. 1927.Wir fanden inzwischen auch im Harn der trächtigen Kuh und des Neugeborenen Ovarial-hormon.