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排序方式: 共有627条查询结果,搜索用时 15 毫秒
31.
C.H. Bastien T. Ceklic P. St-Hilaire F. Desmarais A.D. Pérusse J. Lefrançois M. Pedneault-Drolet 《Pathologie-biologie》2014
Sleep misperception is often observed in insomnia individuals (INS). The extent of misperception varies between different types of INS. The following paper comprised sections which will be aimed at studying the sleep EEG and compares it to subjective reports of sleep in individuals suffering from either psychophysiological insomnia or paradoxical insomnia and good sleeper controls. The EEG can be studied without any intervention (thus using the raw data) via either PSG or fine quantitative EEG analyses (power spectral analysis [PSA]), identifying EEG patterns as in the case of cyclic alternating patterns (CAPs) or by decorticating the EEG while scoring the different transient or phasic events (K-Complexes or sleep spindles). One can also act on the on-going EEG by delivering stimuli so to study their impact on cortical measures as in the case of event-related potential studies (ERPs). From the paucity of studies available using these different techniques, a general conclusion can be reached: sleep misperception is not an easy phenomenon to quantify and its clinical value is not well recognized. Still, while none of the techniques or EEG measures defined in the paper is available and/or recommended to diagnose insomnia, ERPs might be the most indicated technique to study hyperarousal and sleep quality in different types of INS. More research shall also be dedicated to EEG patterns and transient phasic events as these EEG scoring techniques can offer a unique insight of sleep misperception. 相似文献
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33.
Joubert Bastien Belbezier Aude Haesebaert Julie Rheims Sylvain Ducray François Picard Géraldine Rogemond Véronique Psimaras Dimitri Berzero Giulia Desestret Virginie Honnorat Jérôme 《Journal of neurology》2020,267(7):2083-2089
Journal of Neurology - To assess the long-term outcomes of patients with temporal lobe epilepsy and CSF anti-glutamate decarboxylase antibodies (GAD65-Abs). We retrospectively analyzed the clinical... 相似文献
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35.
Villagrán-García Macarena Muñiz-Castrillo Sergio Ciano-Petersen Nicolás Lundahl Vogrig Alberto Farina Antonio Villard Marine Psimaras Dimitri Alentorn Agusti Gonçalves David Fabien Nicole Rogemond Véronique Joubert Bastien Honnorat Jérôme 《Journal of neurology》2023,270(1):283-299
Journal of Neurology - The link between paraneoplastic neurological syndromes (PNS) and renal cell and bladder cancer (RCC/BC) is rare and uncertain. Our aim was to clinically evaluate, in light of... 相似文献
36.
Goasguen N Bourrier A Ponsot P Bastien L Lesurtel M Prat F Dousset B Sauvanet A 《American journal of surgery》2009,197(6):715-3564
Background
Preoperative endoscopic pancreatic sphincterotomy (EPS) has been proposed to prevent postoperative pancreatic fistula (POPF) after distal pancreatectomy (DP) or enucleation (EN). The use of EPS as a curative treatment for POPF has been scarcely reported. We reported 10 consecutive patients who were successfully treated by EPS for a prolonged POPF.Study design
Ten patients underwent EPS for prolonged POPF (median duration = 40 days, range 20-114; median daily output = 80 mL, range 50-250) after 6 DPs, 2 ENs, and 2 medial pancreatectomies.Results
EPS was performed in all patients, with stent insertion in 4. No patient developed a specific complication because of EPS. POPF healed within a median delay of 4 days (range 1-12). One patient underwent a repeated endoscopy to treat stent malposition. The median delay of discharge after EPS was 13 days (range 8-15). With a 20-month median follow up, 1 patient developed early transient POPF recurrence because of spontaneous stent migration.Conclusions
EPS is indicated for prolonged POPF after DP or EN because it is highly feasible, shortens healing, and is well tolerated. 相似文献37.
38.
Bastien Dietemann Larissa Wahl Nahum Travitzky Harald Kruggel-Emden Torsten Kraft Claas Bierwisch 《Materials》2022,15(6)
This work considers the fabrication of ceramic parts with the help of an additive manufacturing process, robocasting, in which a paste with suspended particles is robotically extruded. Within the final part, the material properties depend on the orientation of the particles. A prediction of the particle orientation is challenging as the part usually undergoes multiple processing steps with varying contributions to the orientation. As the main contribution to the final particle orientation arises from the extrusion process, many corresponding prediction models have been suggested. Robocasting involves, however, further processing steps that are less studied as they have a smaller influence on the orientation. One of the processing steps is drying by natural convection, which follows directly after the extrusion process. A quantification of the reorientation that occurs during drying is mostly unknown and usually neglected in the models. Therefore, we studied the amount of reorientation of suspended particles in robocasted green filaments during drying in detail. For our study, we applied the discrete element method, as it meets various requirements: The exact particle geometry can be resolved precisely; particle–particle interactions can be described; the paste composition is reproduced exactly; the initial particle orientation can be set in accordance with the prediction from the analytical models for the extrusion part; macroscopic force laws exist to represent capillary forces due to the remaining fluid phase that remains during drying. From our study, we concluded that the magnitude of particle reorientation during drying is small compared to the orientation occurring during the extrusion process itself. Consequently, reorientation during drying might further be neglected within analytical orientation prediction models. 相似文献
39.
Sophie Auger Mattea Orsini Patrice Céballos Nathalie Fegueux Tarik Kanouni Bastien Caumes Bernard Klein Martin Villalba Jean‐François Rossi 《European journal of haematology》2014,92(5):421-428
Epstein–Barr virus reactivation (EBV‐R) frequently occurs in patients having allogeneic hematopoietic stem cell transplantation (HSCT). We evaluated the impact of controlled EBV‐R on survival of 190 patients (114M/76F, median age: 51 yr, range 18–69), having HSCT for hematological malignancies (105 acute leukemias and myelodysplasias, 71 lymphoproliferative disorders, 14 others). Overall survival (OS) and progression‐free survival (PFS) were compared between patients with and without EBV‐R. Of 138, patients had reduced‐intensity conditioning regimen. Various stem cell sources (141 PB, 33 umbilical cord blood and 16 bone marrow) were used. Patients with EBV‐R had longer PFS and OS than those without EBV‐R: PFS at 2 yr 69% vs. 51% and at 5 yr 47% vs. 38% (P < 0.04); OS at 2 yr 76% vs. 64% and at 5 yr 63% vs. 47%) (P < 0.001). The use of rituximab had no impact on OS and PFS, but it reduced the intensity of GVHD, despite the fact that TRM was not significantly different between the two groups of patients. So, rituximab may have an additional effect to other factors on PFS and OS. In multivariate analysis, antithymocyte globulin administration was not a significant factor for PFS (P = 0.68) and for OS (P = 0.81). Circulating NK cells were significantly increased by 22% (P = 0.03) in EBV‐R patients with no differences for other parameters. Controlled EBV‐R in the setting of HSCT is associated with better OS and PFS, with a significant increase in circulating NK cells. 相似文献
40.
Cardiovascular effects of concomitant administration of isoflurane and nicorandil in dogs 总被引:3,自引:1,他引:2
Piriou V.; Ross S.; Bastien O.; Pigott D.; Trivin F.; Foex P. 《British journal of anaesthesia》1998,80(4):481-487
Nicorandil, a new KATP channel opener, is used in clinical practice for
anti-anginal therapy. It exhibits vasodilator properties as does the
halogenated anaesthetic isoflurane. We have examined the cardiovascular
effects of increasing concentrations of isoflurane after administration of
nicorandil in 10 adult beagle dogs anaesthetized with thiopental and whose
lungs were ventilated mechanically. During surgery, anaesthesia was
maintained with 1.0-1.5% isoflurane. A left thoracotomy was performed and
the heart suspended in a pericardial cradle. Monitoring included: ECG;
aortic, left ventricular, arterial, central venous and pulmonary artery
pressures; cardiac output; coronary flow; and segmental length in the
apical region. After surgery, isoflurane anaesthesia was set at an
end-tidal concentration of 1.05% (1 MAC) and measurements obtained; these
were repeated with 1.4%, 1.75%, 2.1% and 1.05% isoflurane concentrations
after appropriate stabilization periods. Nicorandil (100 micrograms kg-1
bolus, 25 micrograms kg-1 min- 1 infusion) was begun and a second
dose-response study of isoflurane was obtained as before. Blood samples
were obtained for measurement of concentrations of nicorandil. Systolic
ventricular function was assessed by systolic shortening (%SS) and preload
recruitable stroke work (PRSW). Increasing isoflurane concentration
produced decreases in heart rate, systolic pressure, cardiac output, %SS
and PRSW. Nicorandil produced a slight decrease in systolic arterial
pressure (10 and 15 mm Hg after 1.05% and 2.05% isoflurane) and a slight
increase in heart rate (10 and 5 beat min-1 after 1.05% and 2.05%
isoflurane). Preload, assessed by end-diastolic length, decreased. Coronary
blood flow increased with infusion of nicorandil. Left ventricular function
was not affected by infusion of nicorandil. We conclude that nicorandil has
only minor vaso/venodilatory effects in the presence of isoflurane.
Ventricular function was not altered by infusion of nicorandil.
相似文献