全文获取类型
收费全文 | 5433篇 |
免费 | 232篇 |
国内免费 | 17篇 |
专业分类
耳鼻咽喉 | 175篇 |
儿科学 | 428篇 |
妇产科学 | 216篇 |
基础医学 | 511篇 |
口腔科学 | 110篇 |
临床医学 | 293篇 |
内科学 | 919篇 |
皮肤病学 | 123篇 |
神经病学 | 440篇 |
特种医学 | 102篇 |
外科学 | 1033篇 |
综合类 | 81篇 |
预防医学 | 252篇 |
眼科学 | 164篇 |
药学 | 426篇 |
中国医学 | 34篇 |
肿瘤学 | 375篇 |
出版年
2023年 | 32篇 |
2022年 | 78篇 |
2021年 | 163篇 |
2020年 | 102篇 |
2019年 | 103篇 |
2018年 | 137篇 |
2017年 | 112篇 |
2016年 | 139篇 |
2015年 | 176篇 |
2014年 | 239篇 |
2013年 | 307篇 |
2012年 | 415篇 |
2011年 | 467篇 |
2010年 | 301篇 |
2009年 | 207篇 |
2008年 | 377篇 |
2007年 | 337篇 |
2006年 | 350篇 |
2005年 | 324篇 |
2004年 | 268篇 |
2003年 | 237篇 |
2002年 | 247篇 |
2001年 | 47篇 |
2000年 | 38篇 |
1999年 | 37篇 |
1998年 | 54篇 |
1997年 | 34篇 |
1996年 | 30篇 |
1995年 | 36篇 |
1994年 | 25篇 |
1993年 | 27篇 |
1992年 | 9篇 |
1991年 | 17篇 |
1990年 | 24篇 |
1989年 | 21篇 |
1988年 | 22篇 |
1987年 | 20篇 |
1986年 | 14篇 |
1985年 | 20篇 |
1984年 | 17篇 |
1983年 | 10篇 |
1982年 | 11篇 |
1981年 | 14篇 |
1980年 | 9篇 |
1979年 | 11篇 |
1978年 | 6篇 |
1977年 | 2篇 |
1976年 | 4篇 |
1970年 | 3篇 |
1967年 | 1篇 |
排序方式: 共有5682条查询结果,搜索用时 15 毫秒
101.
A simple synthetic strategy has been developed for the synthesis of 2- and 1-alkyl/aryl/dialkylaminoquinolines and isoquinolines from the easily available quinoline and isoquinoline-N-oxides, different amines, triflic anhydride as activating agent and acetonitrile as solvent in a one-pot reaction under metal-free conditions at 0 °C to room temperature.A synthetic strategy has been developed for synthesis of 2 and 1-aminoquinolines and isoquinolines from quinoline and isoquinoline-N-oxides, amines and triflic anhydride in acetonitrile at 0 °C to room temperature. 相似文献
102.
Sudipta Saha Manoj Andley Vivek Gautam Saurabh Gyan Ashok Kumar Ajay Kumar 《Indian Journal of Thoracic and Cardiovascular Surgery》2013,29(2):140-142
Carcinosarcoma of esophagus contains both the carcinomatous and sarcomatous elements. These are rare polypoidal malignancies of esophagus. One such case is presented and available literature is reviewed. 相似文献
103.
Ashok Kumar Himanshu Gupt Chandra Shekhar Yadav Shah Alam Khan Shishir Rastogi 《中华创伤杂志(英文版)》2013,16(1):22-26
Objective:To present our experience in treatment of difficult ununited long bone fractures with locking plate.Methods:Retrospective evaluation of locking plate fixation in 10 difficult nonunions of lon... 相似文献
104.
105.
Prophylactic Central Neck Dissection in Differentiated Thyroid Cancer: An Assessment of the Evidence
David E. Gyorki MD Brian Untch MD R. Michael Tuttle MD Ashok R. Shaha MD 《Annals of surgical oncology》2013,20(7):2285-2289
An area of ongoing controversy in the management of patients with differentiated thyroid cancer is the role of prophylactic central neck dissection (pCND). This review describes the natural history of differentiated thyroid cancer and provides the limited data regarding the role of routine pCND. An evidence-based analysis was performed of the rationale for routine pCND was performed, including reduced rates of central neck recurrence, reduced morbidity with secondary central neck lymphadenectomy, improved rates of postoperative athyroglobulinemia, and improved stratification of radioactive iodine (RAI) dosage. A critical appraisal of the available literature demonstrates insufficient evidence to indicate that this extra procedure performed routinely leads to improvement in clinically meaningful end points. 相似文献
106.
107.
108.
Manpreet Kaur Charanjit Lal Dipankar Bhowmik Ashok Kumar Jaryal Kishore Kumar Deepak Sanjay Kumar Agarwal 《Clinical and experimental nephrology》2013,17(1):134-139
Background
Patients of end stage renal disease (ESRD) have an increased risk of cardiovascular events. Arterial stiffness is an established independent predictor of cardiovascular morbidity and mortality in ESRD patients. Carotid femoral pulse wave velocity (c-f PWV) and augmentation index (AI) are the indices which are used for the noninvasive assessment of arterial stiffness. Renal transplantation (RT) as a treatment modality in ESRD patients is associated with improvement in cardiovascular survival. Whether this improvement is due to attenuation of arterial stiffness has been inadequately investigated. The present study was conducted in ESRD patients before and 3 months after RT to assess the reversibility of the abnormalities of vascular compliance that are known to be associated with adverse outcome.Methods
Arterial stiffness indices (c-f PWV and AI) were measured using the principle of applanation tonometry with a SphygmoCor® CvMS system (Atcor Medicals, Australia) in 23 ESRD patients (age: 35.9 ± 9.3 years) before and 3 months after successful RT.Results
After transplantation, augmentation index values reduced significantly as compared to their pre-transplant values (27.7 ± 11.3 % vs. 17.1 ± 9.0 %; P < 0.0001), while the carotid femoral pulse wave velocity values did not differ significantly (8.7 ± 2.0 vs. 8.6 ± 3.2 m/s). The augmentation index was correlated with the biochemical parameters of serum creatinine (Pearson r = 0.3628; P = 0.0128) and calcium phosphate product (Pearson r = 0.3868; P = 0.0079).Conclusions
Restoration of renal function following successful RT is associated with differential effects on the two indices of arterial stiffness. The salient finding of our study is that 3 months after transplantation, functional changes in vasculature lead to a significant reduction in the augmentation index, while the pulse wave velocity may take longer to show an improvement. 相似文献109.
Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease in adults. The biologic basis of ALS remains unknown. However, ALS research has taken a dramatic turn over the past 4 years. Ground breaking discoveries of mutations of genes that encode RNA processing proteins, and demonstration that abnormal aggregates of these and other proteins precede motor neuron loss in familial and sporadic ALS, have initiated a paradigm shift in understanding the pathogenic mechanisms of ALS. Curiously, some of these RNA binding proteins have prion‐like domains, with a propensity to self‐aggregation. The emerging hypothesis that a focal cascade of toxic protein aggregates, and their consequent non–cell‐autonomous spread to neighborhood groups of neurons, fits the classical temporo‐spatial progression of ALS. This article reviews the current research efforts toward understanding the role of RNA‐processing regulation and protein aggregates in ALS. Muscle Nerve 47:330‐338, 2013 相似文献
110.
Yafit Gilboa Ashok Jansari Bernadette Kerrouche Emel Uçak Anne Tiberghien Ouarda Benkhaled 《Neuropsychological rehabilitation》2013,23(9):1359-1382
ABSTRACTObjectives: The Jansari assessment of Executive Functions for Children (JEF-C©) is a new non-immersive computerised assessment of executive functions. The objectives of the study were to test the feasibility and validity of JEF-C© in children and adolescents with acquired brain injury (ABI).Methods: Twenty-nine patients with ABI aged 10–18 years and 30 age-and gender-matched controls were tested. Participants performed JEF-C©, Wechsler Abbreviated Scale of Intelligence (WASI) and the Behavioural Assessment of the Dysexecutive Syndrome for Children (BADS-C), while parents completed the Behaviour Rating Inventory of Executive Function (BRIEF) questionnaire.Results: The JEF-C© task proved feasible in patients with ABI. The internal consistency was medium (Cronbach’s alpha?=?0.62 and significant intercorrelations between individual JEF-C© constructs). Patients performed significantly worse than controls on most of the JEF-C© subscales and total score, with 41.4% of participants with ABI classified as having severe executive dysfunction. No significant correlations were found between JEF-C© total score, the BRIEF indices, and the BADS-C. Significant correlations were found between JEF-C© and demographic characteristics of the sample and intellectual ability, but not with severity/medical variables.Conclusion: JEF-C© is a playful complex task that appears to be a sensitive and ecologically valid assessment tool, especially for relatively high-functioning individuals. 相似文献