全文获取类型
收费全文 | 23111篇 |
免费 | 1644篇 |
国内免费 | 62篇 |
专业分类
耳鼻咽喉 | 226篇 |
儿科学 | 914篇 |
妇产科学 | 773篇 |
基础医学 | 2928篇 |
口腔科学 | 237篇 |
临床医学 | 3003篇 |
内科学 | 3960篇 |
皮肤病学 | 519篇 |
神经病学 | 2285篇 |
特种医学 | 465篇 |
外科学 | 2343篇 |
综合类 | 252篇 |
一般理论 | 37篇 |
预防医学 | 3254篇 |
眼科学 | 301篇 |
药学 | 1555篇 |
中国医学 | 21篇 |
肿瘤学 | 1744篇 |
出版年
2024年 | 32篇 |
2023年 | 284篇 |
2022年 | 359篇 |
2021年 | 786篇 |
2020年 | 487篇 |
2019年 | 807篇 |
2018年 | 831篇 |
2017年 | 620篇 |
2016年 | 646篇 |
2015年 | 688篇 |
2014年 | 941篇 |
2013年 | 1354篇 |
2012年 | 2056篇 |
2011年 | 2187篇 |
2010年 | 1122篇 |
2009年 | 1008篇 |
2008年 | 1597篇 |
2007年 | 1691篇 |
2006年 | 1520篇 |
2005年 | 1330篇 |
2004年 | 1172篇 |
2003年 | 1049篇 |
2002年 | 934篇 |
2001年 | 125篇 |
2000年 | 66篇 |
1999年 | 102篇 |
1998年 | 157篇 |
1997年 | 89篇 |
1996年 | 75篇 |
1995年 | 74篇 |
1994年 | 60篇 |
1993年 | 42篇 |
1992年 | 39篇 |
1991年 | 33篇 |
1990年 | 35篇 |
1989年 | 28篇 |
1988年 | 36篇 |
1987年 | 44篇 |
1986年 | 47篇 |
1985年 | 31篇 |
1984年 | 44篇 |
1983年 | 34篇 |
1982年 | 20篇 |
1981年 | 14篇 |
1980年 | 10篇 |
1979年 | 14篇 |
1978年 | 10篇 |
1976年 | 12篇 |
1974年 | 19篇 |
1973年 | 10篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
31.
Although psychological debriefing (PD) represents the most common form of early intervention for recently traumatized people, there is little evidence supporting its continued use with individuals who experience severe trauma. This review identifies the core issues in early intervention that need to be addressed in resolving the debate over PD. It critiques the available evidence for PD and the early provision of cognitive-behavioral therapy (CBT). Based on available evidence, we propose that psychological first aid is an appropriate initial intervention, but that it does not serve a therapeutic or preventive function. When feasible, initial screening is required so that preventive interventions can be used for those individuals who may have difficulty recovering on their own. Evidence-based CBT approaches are indicated for people who are at risk of developing posttraumatic psychopathology. Guidelines for managing acutely traumatized people are suggested and standards are proposed to direct future research that may advance our understanding of the role of early intervention in facilitating adaptation to trauma. 相似文献
32.
33.
The anatomy responsible for the sonographic diagnosis of the renal “junctional parenchymal defect” and “interrenicular septum”
is caused by perirenal fat along a line of incomplete fusion of two primary renal lobes. Studies using CT, MRI and cadaver
observations are presented. “Oddono's sulcus” is suggested as a name for the changes in honor of the author who first described
these anatomic findings.
Received: 12 January 1996 Accepted: 16 January 1996 相似文献
34.
35.
Kathleen Matuska Amy Giles-Heinz Nancy Flinn Michael Neighbor Julie Bass-Haugen 《The American journal of occupational therapy》2003,57(2):220-224
OBJECTIVE: The purpose of this study was to evaluate a pilot occupational therapy wellness program designed to teach elders the importance of participation in meaningful social and community occupations to their quality of life. METHOD: Sixty-five older adults participated in this pilot wellness program held at each of three senior apartment complexes. Measures of health-related quality of life using the SF-36 Health Survey and frequencies of social and community participation from a program-specific intake form were completed by 39 participants before and after the 6-month program. Participants also evaluated components of the program through a satisfaction survey. RESULTS: Scores on the SF-36 Health Survey were significantly higher in vitality, social functioning, and the mental health summary scores following participation in the program. Participants reported an increased frequency of socialization and community participation with an average of 55% participating in at least three or more activities per week before the program to an average of 66% participating after the program. Participants who benefited the most attended more classes, were older, and were nondrivers. Eighty percent of those polled rated the pilot program as good or excellent. CONCLUSION: This pilot study provides additional support for prevention efforts for elders in the community. Wellness programs for seniors may be most effective if targeted to those who are older and nondrivers. 相似文献
36.
Cesare Mondadori Conrad Gentsch Bastian Hengerer Thomas Ducret Jürgen Borkowski Amy Racine Renate Lederer Albert Haeusler 《Psychopharmacology》1992,109(4):383-389
Oral pretreatment with aldosterone or corticosterone blocked the memory-enhancing effects of the calcium antagonist nimodipine, the ACE inhibitor captopril, the NMDA blocker CGP 37 849, and the glycine antagonist strychnine in a passive-avoidance test in mice. The memory-disturbing effects of phenobarbitone, diazepam, CGP 37 849 and scopolamine were not influenced by the hormonal pretreatment. These findings could indicate the involvement of a steroid-sensitive mechanism in drug-induced improvement of memory. In the light of clinical observations showing elevated cortisol levels in Alzheimer patients, the results might also explain why only a limited number of these patients respond to therapy with memory enhancers. 相似文献
37.
B C Yankaskas M H Knelson M L Abernethy J T Cuttino R L Clark 《Investigative radiology》1988,23(10):729-733
From January 1980 through June 1986, 199 percutaneous needle localizations for clinically occult breast lesions were performed at North Carolina Memorial Hospital. A retrospective analysis of the medical records, mammograms, operative notes, and pathology reports was undertaken to evaluate the success of this procedure. In our series, biopsy was prompted by abnormal calcifications in 27.1% of lesions, occult masses in 37.2%, and by a combination of occult masses and microcalcification in 35.7%. Overall, we had a yield of positive biopsies for cancer of 16.3%, with the yield improving from 12.3% in the earlier years of our study, to 18.7% in the latter years. Of the cancer cases detected, 89.7% were stage I. The localization procedure was successful in 95.9% of the cases. Analysis of our eight failures, along with a review of the literature, shows the major reasons for failure to be incomplete removal of areas with multiple calcifications, dislodgement of the needle, and problems resulting from lack of communication between the radiologist and surgeon. We conclude that the failure rate is low, the yield good, and needle localization a worthwhile procedure for localizing nonpalpable occult lesions. 相似文献
38.
Margaret A. O’Leary Brian Prakash Krishnan Amy McKendry Geoffrey K. Isbister 《Toxicon》2007,50(2):206-213
Recently it has been suggested that the Australian snake antivenoms made by CSL Ltd. are in fact not truly monovalent and may contain antibodies to other snake venoms because the horses are injected with multiple snake venoms. It is unclear to what extent various monovalent antivenoms can neutralise the effect of other venoms, whether this is due to a mixture of antibodies or true cross-reactivity, and whether this has any clinical significance. We aimed to study the immunological and functional properties of brown snake (Pseudonaja spp.) antivenom (BSAV) and tiger snake (Notechis spp.) antivenom (TSAV) against their respective venoms using enzyme immunoassays (EIA) and in vitro clotting studies. There was significant overlap between the two antivenoms with both TSAV and BSAV being detected by EIA on brown snake venom (BSV)-coated and tiger snake venom (TSV)-coated wells, respectively. In a competition EIA, increasing amounts of immunoaffinity-purified hen anti-brown antibodies (IgYp) mixed with TSAV reduced TSAV measured on TSV-coated wells. Both BSAV and TSAV prevented the clotting activity of both venoms. IgYp also prevented the clotting activity of TSV, suggesting true cross-reactivity. The cross-reactivity of TSAV and BSAV with BSV and TSV, respectively, was likely due to each being a mixture of anti-brown and anti-tiger antibodies, but there was partial cross-reactivity demonstrated by the effect of IgYp. Single-polyvalent antivenom for brown snake and tiger snake may be feasible in the future. 相似文献
39.
The impact of food allergy: the real "fear factor". 总被引:1,自引:0,他引:1
40.
Deborah D Albright Diane Jordan-Wagner Diane C Napoli Amy L Parker Fonzie Quance-Fitch Bonnie Whisman Jacob W Collins Larry L Hagan 《Annals of allergy, asthma & immunology》2006,97(4):521-527
BACKGROUND: Multicolored Asian lady beetles (Harmonia axyridis) have been used as a biological control agent against crop-destroying aphids in the United States. Outside their natural habitat, H. axyridis seeks refuge in homes during fall and winter, leading to patient complaints and symptoms of rhinitis, wheezing, and urticaria on exposure to the beetles. OBJECTIVE: To gain a better understanding of the character and spectrum of allergic disease provoked by exposure to home-infesting lady beetles. METHODS: Eight patients with allergic symptoms suspected of being caused by H. axyridis and consistent with an IgE-mediated process were identified and interviewed. A whole-body extract from H. axyridis was prepared. Western blots using the patients' serum identified specific IgE antibodies in the extract. Through a novel technique, immunohistochemical analysis using beetle sections overlayed with patient serum was performed. A random survey of allergists from across the United States was also performed to evaluate experience with cases of lady beetle allergy. RESULTS: Western blots revealed IgE binding to 5 proteins with molecular weights of approximately 8.6, 21, 28, 31, and 75 kDa. Specific IgE bound to proteins localized in the beetle's mouth and leg areas. The allergist survey revealed positive responses in North Central, Mid-Atlantic and New England states. CONCLUSION: In 8 patients with allergic symptoms on exposure to high levels of lady beetles, specific IgE bound to proteins from H. axyridis. There was also an increased frequency of suspected cases of lady beetle allergy in endemic areas. 相似文献