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11.
Isoshima Daichi Yamashiro Keisuke Matsunaga Kazuyuki Taniguchi Makoto Matsubara Takehiro Tomida Shuta Ota Shinzo Sato Michiyoshi Shimoe Yutaka Kohriyama Tatsuo Arias Zulema Omori Kazuhiro Yamamoto Tadashi Takashiba Shogo 《Odontology / the Society of the Nippon Dental University》2021,109(1):239-249
Odontology - There is no conclusive evidence regarding a causal relationship between periodontitis and atherosclerosis. In this study, we examined the microbiome in the oral cavity and atheromatous... 相似文献
12.
Mihoko Tomida Hidetsugu Tsujigiwa Keisuke Nakano Rina Muraoka Takami Nakamura Norimasa Okafuji Hitoshi Nagatsuka Toshiyuki Kawakami 《International journal of medical sciences》2013,10(10):1321-1326
Background: Bone marrow-derived cells (BMCs) have abilities of cell migration and differentiation into tissues/organs in the body and related with the differentiation of teeth or periodontal tissue including fibroblasts. Then, we examined the effect of orthodontic mechanical stress to the transplanted BMC migration into periodontal tissues using BMC transplantation model.Material and Method: BMC from green fluorescence protein (GFP) transgenic mice were transplanted into 8-week-old female C57BL/6 immunocompromised recipient mice, which had undergone 10 Gy of lethal whole-body-irradiation. Five mice as experimental group were received orthodontic mechanical stress using separator between first molar (M1) and second molar (M2) 1 time per week for 5 weeks and 5 mice as control group were not received mechanical stress. The maxilla with M1 and M2 was removed and was immunohistochemically analyzed using a Dako Envision + Kit-K4006 and a primary anti-GFP-polyclonal rabbit antibody. Immunohistochemically stained was defined as positive area and the pixel number of positive area in the periodontal tissue was compared with the previously calculated total pixel number of the periodontal tissue.Results: The immunohistochemistry revealed that GFP positive cells were detected in the periodontal tissues, both in the experimental and control specimens. The ratio of pixel number in the examination group showed 5.77 ± 3.24 % (mean ± SD); and that in the control group, 0.71±0.45 % (mean ± SD). The examination group was significantly greater than that of control group (Mann-Whitney U test: p<0.001).Conclusion: These results suggest that orthodontic mechanical stress accelerates transplanted BMC migration into periodontal tissues. 相似文献
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Shimpei Yamada Ken Tomida Genichi Tanino Akira Suzuki Kenji Kawakami Shinji Kubota Ryuzo Yanohara Youhei Katoh Yosuke Wada Toshio Teranishi Abbas Orand Yutaka Tomita Shigeru Sonoda 《Journal of Physical Therapy Science》2015,27(4):1247-1250
[Purpose] The purpose of this study was to find whether a fast treadmill gait training
speed is effective for the gait training of stroke patients in the early rehabilitation
stage. [Subjects and Methods] Thirty-nine stroke patients were the subjects of our
investigation. They walked on a treadmill with handrail supports at a fast speed (130% of
their comfortable gait speed in the 2nd week). The treadmill gaits of the patients were
recorded using a 3-dimensional analysis system at two and six weeks after their
admissions. Intraclass Correlation Coefficients (ICC) of the temporal and spatial
parameters of the two periods were statistically analyzed. [Results] For all of the
patients, the ICCs of the measured parameters were greater than 0.58. In the case of
patients whose gait speeds of the two periods were close, the ICC units were greater than
0.7. [Conclusion] The fast gait speed training allowed us to expose the patients to a gait
speed that they were expected to acquire at a later stage of their rehabilitation. This
training method was found to be beneficial for the mildly paralyzed patients.Key words: Stroke, Treadmill, Fast speed 相似文献
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Oyama K Tsujimoto A Otsuka E Shimizu Y Shiratsuchi K Tsubota K Takamizawa T Miyazaki M 《Dental materials journal》2012,31(1):26-31
We compared the surface free energies and enamel bond strengths of single-step self-etch adhesives with and without an oxygen-inhibited layer. The adhesives were applied to the enamel surfaces of bovine incisors, light irradiated, and the oxygen-inhibited layer was either retained or removed with ethanol. The surface free energies and their components (γ(S)(LW), γ(S)(+), and γ(S)(-)) were determined by measuring the contact angles of three test liquids placed on the cured adhesives. The enamel bond strengths of specimens with and without the oxygen-inhibited layer were measured. For all surfaces, the value of the estimated surface tension component γ(S)(LW) was relatively constant. The value of the γ(S)(+) component increased slightly when the oxygen-inhibited layer was removed, whereas that of the γ(S)(-) component decreased significantly. The enamel bond strengths of the self-etch adhesives were significantly lower in the specimens without an oxygen-inhibited layer. The oxygen-inhibited layer therefore appeared to promote higher enamel bond strength. 相似文献
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Aya Miyazaki Hideki Uemura Yasuyo Takeuchi Junya Tomida Yasuo Ono Yoshifumi Fujimoto Norie Mitsushita Akio Ikai 《Congenital heart disease》2022,17(6):647-652
Appropriate heart rate in a failing pulmonary ventricle remains unknown, particularly in congenital heart disease with unique hemodynamics. A 71-year-old male with repaired tetralogy of Fallot and a pacemaker for a sinus node dysfunction suffered from heart failure symptoms with preserved left ventricular function. Simply changing the pacemaker’s lower rate from 60 to 75 bpm, New York Heart Association classification improved from III to II, and hemodynamic parameters drastically improved. We regarded this case as informative. Appropriate heart rate could be higher in congenital patients with failing right and non-failing left ventricles than in adults with malfunctioning LV. 相似文献
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Eri Hagiwara Takuma Katano Kohsuke Isomoto Ryota Otoshi Hideaki Yamakawa Ryo Okuda Akimasa Sekine Tomohisa Baba Shigeru Komatsu Takashi Ogura 《Respiratory investigation》2019,57(1):54-59