Clinical observation on electroacupuncture plus tuina for chronic tension-type headache

Objective

To observe the clinical efficacy of electroacupuncture (EA) combined with tuina for chronic tension-type headache (CTTH).

Methods

A total of 97 CTTH cases were randomly allocated into an observation group (n=52) and a control group (n=45). Patients in the observation group were treated with EA plus tuina based on pattern identification, whereas patients in the control group were treated with oral amitriptyline and oryzanol. Patients in both groups were treated for 8 weeks. A follow-up was conducted 3 months after the treatment. The intensity, duration, and frequency of the headache were recorded and compared before and after the treatment. Additionally, the patients’ psychological state and quality of life (QOL) were compared between the two groups.

Results

There were intra-group statistically significant differences in headache intensity score, headache duration, and headache frequency after the treatment and during the follow-up compared with those before the treatment (all P<0.05); and there were between-group statistically significant differences during the same time frame (all P<0.05). The Hamilton depression scale-17 items (HAMD-17) and Hamilton anxiety scale (HAMA) scores were significantly reduced in both groups after the treatment or during the follow-up (all P<0.01); and there were no between-group statistical significances during the same time frame (all P>0.05). The World Health Organization quality of life-BREF (WHOQOL-BREF) scores were significantly reduced in both groups after the treatment or during the follow-up (all P<0.05); and the scores in the observation group were significantly lower than those in the control group (all P<0.05) during the same time frame. The total effective rate was 88.0% in the observation group, versus 71.4% in the control group, showing a significant difference (P<0.05).

Conclusion

EA combined with tuina can significantly decrease the frequency of chronic tension-type headache, alleviate headache intensity, shorten headache duration, and improve the patients’ wellness. It is better than amitriptyline plus oryzanol.

     

TRPV5在含钙肾结石患者肾组织中表达的临床研究

目的 探讨TRPV5在肾组织中的表达对于含钙肾结石形成的影响.方法 选取2012年1月～2012年10月在本院接受微创经皮肾镜取石术的56例肾结石患者（分为含钙结石组30例,非含钙结石组26例）进行研究,并选取同期因其他非肾结石原因接受肾脏切除的20例患者为对照组进行对比研究,三组患者均进行24h尿钙以及肾组织TRPV5免疫组化的检测.结果 含钙结石组的24h尿钙为8.59＆#177;2.48mmol,高于非含钙结石组（6.14＆#177;1.74 mmol;P＜0.05）和对照组（6.29＆#177;1.80 mmol;P＜0.05）.免疫组化检测含钙结石组肾组织中TRPV5强表达3例、中表达7例、低表达20例;非含钙结石组肾组织中TRPV5强表达16例、中表达7例、低表达3例;对照组肾组织中TRPV5强表达11例、中表达8例、低表达1例,含钙结石组肾组织TRPV5的表达与其他两组比较,均有统计学差异（P＜0.05）.结论 肾组织中TRPV5表达的减少可能是导致含钙肾结石形成的机制之一.     

尿道下裂尿道成形术后尿瘘的治疗

目的总结尿道下裂尿道成形术后并发尿瘘的治疗经验。方法28例尿道下裂尿道成形术后尿瘘。分别采用结扎包埋法、Y-V皮瓣覆盖法、瘘口连续内翻缝合法、Thiersch法、Denis-Browne法进行尿瘘修复。结果28例患者一次修复成功23例,随访3个月-6年,排尿正常,阴茎外观满意,成功率为82.1％。结扎包埋法、Y-V皮瓣覆盖法、瘘口连续内翻缝合法、Thierseh法、Denis-Browne法一次修复成功率分别为88.9％（8／9）、100％（7／7）、75.0％（3／4）、66.7％（4／6）和50.0％（1／2）。结论尿道下裂尿道成形术后尿瘘的修补有多种术式。应根据尿瘘的部位、大小、数量和局部条件选择不同的手术方法。     

腰椎定点微调整脊法配合以宗四维牵引治疗腰椎管狭窄症临床观察

目的:观察经腰椎定点微调整脊法配合以宗四维牵引治疗后腰椎管狭窄症患者腰曲弓形面积的变化及临床疗效。方法:将60例腰椎管狭窄症患者随机分为2组各30例,治疗组予腰椎定点微调整脊法配合以宗四维牵引治疗,对照组给予口服布洛芬片加腰椎电动牵引治疗。治疗2周,并于治疗前和治疗后做腰椎侧位X片计算弓形面积、用日本骨伤协会(JOA)下腰痛评分表测评计算临床疗效。结果:2组治疗后的弓形面积改善均优于治疗前(P0.001),治疗后治疗组的弓形面积改善优于对照组(P0.001)。经治疗,治疗组和对照组的总改善率(治愈+显效+有效)分别是93.33%和76.67%(P0.05)。显效率(治愈+显效)治疗组为53.34%、对照组26.67%(P0.05)。结论:2种治疗方法均能不同程度改善腰椎管狭窄症患者临床症状体征,其中腰椎定点微调整脊法配合以宗四维牵引治疗较口服布洛芬片加腰椎电动牵引治疗者,在腰曲改善和临床疗效上都有较显著优势。     

克拉霉素分散片制备工艺研究

目的 优化克拉霉素分散片制备工艺.方法 将分散均匀度作为考察指标,利用正交设计试验法,对克拉霉素分散片处方中辅料(微晶纤维素、交联羧甲基纤维素钠、十二烷基硫酸钠和微粉硅胶)用量进行筛选,同时对制备工艺进行相关研究.结果 利用优化后的工艺制成分散片,其各项指标经检测后全部达到标准,并且根据溶出度测试表明,利用该方法制成的...     

舌底刺络放血治疗运动性失语32例

中风失语症是由于脑血管意外致大脑一定区域发生器质性病变而造成的语言缺失,即口语、书面语的表达和理解障碍,它是中风常见伴随症状之一。运动性失语是中风失语症的一种类型,以口语表达障碍为主要表现。近一年多来作者采用舌底剌络放血治疗运动性失语32例,并与传统体针治疗作随机对照,现报告如下。     

口腔癌相关成纤维细胞的研究进展

间质细胞与细胞外基质构成的肿瘤-宿主界面微环境对肿瘤细胞的生长、浸润和转移具有重要作用。其中,癌相关成纤维细胞是最重要的宿主细胞,对口腔癌的发生发展起着重要的作用,以其为靶标所进行的肿瘤间质治疗开拓了肿瘤防治新途径。下面就癌相关成纤维细胞及其来源、与口腔癌的关系和治疗作一综述。     

旋扳手法联合机械牵引治疗腰椎间盘突出症38例临床观察

目的:观察旋扳手法联合机械牵引治疗腰椎间盘突出症(LDH)的临床疗效。方法:将76例LDH患者随机分为治疗组和对照组,每组各38例。对照组采用机械牵引治疗,治疗组在对照组的基础上联合旋扳手法治疗。对比分析2组综合疗效、疼痛视觉模拟评分法(VAS)评分、改良下腰痛日本骨科协会评估治疗分数(JOA)评分及炎性因子。结果:总有效率治疗组为86. 8%(33/38),对照组为73. 7%(28/38),2组比较,差异有统计学意义(P <0. 05)。2组VAS、JOA评分治疗前后组内比较及治疗后组间比较,差异均有统计学意义(P <0. 05)。2组治疗后炎性因子水平均较治疗前下降(P <0. 05),治疗组IL-1β、TNF-α较对照组下降更明显(P <0. 05)。结论:采用旋扳手法联合机械牵引治疗LDH,具有减轻疼痛、恢复功能和消除炎症的效果,安全性及可操作性高,值得临床推广。     

卧位牵顿法配合颈夹脊穴位注射治疗神经根型颈椎病临床疗效观察

目的观察卧位牵顿法配合颈夹脊穴位注射治疗神经根型颈椎病的疗效。方法将72例神经根型颈椎病患者随机分为治疗组39例和对照组33例,治疗组采用卧位牵顿法配合颈夹脊穴位注射治疗;对照组以机械牵引配合口服非甾体炎抗炎药治疗。治疗2个疗程后进行疗效分析。结果治疗组总有效率92.3%,对照组81.8%,2组总有效率比较,差异有显示性意义（P〈0.05）。结论卧位牵顿法配合夹脊穴位注射治疗神经根型颈椎病疗效明显,值得推广。     

腰椎牵顿法治疗腰椎间盘突出症40例临床观察

目的：观察腰椎牵顿法治疗腰椎间盘突出症的疗效。方法：将符合纳入标准的在我院推拿科门诊就诊的75例腰椎间盘突出症患者随机分为治疗组40例和对照组35例,治疗组采用腰椎牵顿法治疗;对照组以腰椎机械牵引治疗。每周治疗5次,每日一次,10天为1疗程。治疗2个疗程后观察疗效。结果：治疗组总有效率92．5％,对照组80．0％,2组总有效率比较,差异有显著性意义（P〈0．05）。结论：腰椎牵顿法治疗腰椎间盘突出症疗效明显,值得推广。