福建省龙岩市碘缺乏病病情监测结果分析

Objective To understand the current situation of iodine deficiency diserders(IDD) in Longyan City and to evaluate the effect of prevention and control measures of IDD in order to provide evidence for formulating prevention and control tactics. Methods During the year of 2006 and 2007, the 30 primary schools were screened by population proportion survey(PPS) from the 7 counties of Longyan City. Forty children aged 8-10 years in each school were randomly selected as a group to examine thyroid, and 7 children in each group were selected to measure the urine iodine and the salt iodine at the same time. The goiter rote, the median urinary iodine, the consumption rate of qualified iodized salt, the iodine salt coverage rate, the rate of qualified iodized salt and the non-iodized rate were detected. Results The goiter rate of children aged 8-10 years old in Longyan City was 0.94%(79/8438). The median urinary iodine was 259.12 μg/L. The consumption rate of qualified iodized salt was 97.86% (1462/1494). The iodine salt coverage rate was 99.46%(1486/1494). The rate of qualified iodized salt was 98.38 (1462/1486), and the non-iodized rate was 0.54% (8/1494). Conclusions All indicators have reached the national standard of eliminating IDD in Longyan City.     

福建省龙岩市碘缺乏病病情监测结果分析

Objective To understand the current situation of iodine deficiency diserders(IDD) in Longyan City and to evaluate the effect of prevention and control measures of IDD in order to provide evidence for formulating prevention and control tactics. Methods During the year of 2006 and 2007, the 30 primary schools were screened by population proportion survey(PPS) from the 7 counties of Longyan City. Forty children aged 8-10 years in each school were randomly selected as a group to examine thyroid, and 7 children in each group were selected to measure the urine iodine and the salt iodine at the same time. The goiter rote, the median urinary iodine, the consumption rate of qualified iodized salt, the iodine salt coverage rate, the rate of qualified iodized salt and the non-iodized rate were detected. Results The goiter rate of children aged 8-10 years old in Longyan City was 0.94%(79/8438). The median urinary iodine was 259.12 μg/L. The consumption rate of qualified iodized salt was 97.86% (1462/1494). The iodine salt coverage rate was 99.46%(1486/1494). The rate of qualified iodized salt was 98.38 (1462/1486), and the non-iodized rate was 0.54% (8/1494). Conclusions All indicators have reached the national standard of eliminating IDD in Longyan City.     

锁骨下带蒂皮瓣修复创伤性手指皮缺损的体会

我院自1986-1996年．选择性采用锁骨下带蒂皮瓣治疗手指外伤48例(52指)。取得较好疗效。现将手术方法及注意事项报道如下。     

乙肝基因疫苗阻断乙肝母婴传播的效果观察

母婴传播是病毒性乙型肝炎的重要传播途径。80年代应用乙肝血源疫苗阻断母婴传播取得了较理想的效果，但要从人血中提取抗原，价格昂贵，且有潜在的安全问题。目前，新一代乙型肝炎表面抗原基因工程疫苗（简称乙肝基因疫苗）已研制成功，其安全性和免疫原性已被证实。1990～1992年在乙型肝炎的高发区广州观察其阻断母婴传播的效果如下：1材料与方法1．1观察对象HBsAg与HBeAg双阳性或HBsAg单阳性的孕妇所生的健康新生儿（足月、顺产、无畸形。无心肺疾患、无发热、无羊水吸人和体重超过2500克）为对象，共观察56例。1．2免疫程序（1）乙…     

纳米银复合生物灭螺剂与氯硝柳胺灭螺效果比较

目的 目的 观察新型纳米银复合生物灭螺剂野外实地灭螺效果, 及其对水生物的毒性影响。方法 方法 选择安徽省池州 市秋浦河下游河滩为研究现场, 挖掘4个1 m3 的水池, 分别设纳米银复合生物灭螺剂300 g/m3 组和600 g/m3 组、 50%氯硝柳 胺乙醇胺盐2 g/m3 组、 天然水对照组, 同时向各水池分别投入100只钉螺、 100尾鲫鱼苗。采用浸杀法, 定期观察同一环境 条件下各组灭螺效果, 以及2种不同药物的鱼毒性影响。结果 结果 纳米银复合生物灭螺剂600 g/m3 组和300 g/m3 组钉螺死亡 率分别在第7 d和第14 d达到100%, 2种剂量的鱼苗死亡率均为6%; 氯硝柳胺组在第3 d的鱼苗死亡率为100%, 第7 d时 钉螺死亡率为100%; 对照组第7 d钉螺死亡率为7%, 第14 d为14%, 鱼苗死亡率为22%。结论 结论 新型纳米银复合生物灭螺 剂具有良好的灭螺效果, 而且对水生动物的生长基本无毒性影响, 有望作为一种新型高效环保型生物灭螺剂推广应用。     

脑室—胸导管分流术(附8例报告)

报告脑室—胸导管分流术治疗各种原因的脑积水8例,除肿瘤4例中2例死亡,影响远期疗效观察外,3/4以上近期疗效比较满意。认为此手术一次成功率较高,无致命的并发症,优于他种分流术。仅限于成人脑积水的治疗,是它的缺陷。     

肿瘤相关抗原CA50监测泌尿男生殖系统恶性肿瘤的临床意义

作者用免疫放射测定法（ＩＲＭＡ）检测了８４例泌尿男生殖系统恶性肿瘤病人，４８例良性疾患病人及３５例正常人的血清ＣＡ５０值。结果发现，恶性肿瘤病人的血清ＣＡ５０值显著高于良性疾患病人及正常人（Ｐ＜０．０５～０．０１）。若以１７ｕ／ｍｌ为诊断界值，其阳性率分别为：肾细胞癌５５％（１１／２０），肾盂及输尿管癌８７％（７／８），膀胱癌６５％（３０／４６），男生殖系恶性肿瘤７０％（７／１０）。其敏感性为６６％（５５／８４），特异性为８８％（４２／４８）。ＣＡ５０水平的测定还能用于对疗效的评价及对肿瘤复发的预测。     

掺钕钇铝石榴石激光局部照射加全膀胱光动力疗法治疗膀胱癌

应用掺钕钇铝石榴石（简称Ｎｄ：ＹＡＧ）激光局部照射加全膀胱光动力疗法（ＰＤＴ）治疗膀胱移行上皮癌患者２０例，共５１个肿瘤，治愈率达９５％。疗后随诊３～２３个月，其肿瘤复发率为１０％。结果提示：Ｎｄ：ＹＡＧ激光可有效地消除膀胱的局部肿瘤，且可加强光动力疗法对局部肿瘤的作用；而全膀胱光动力疗法又可补充Ｎｄ：ＹＡＧ激光膀胱潜在病变控制的不足，有效地消除全膀胱的散在微小病灶，进而提高膀胱癌的治愈率，减少其复发率。     

肾虚矮小症雄性大鼠骨代谢异常及艾灸和运动综合方案干预的研究

目的:从骨细胞形态学和骨细胞生长发育的微环境,探讨观察艾灸和运动综合方案防治雄鼠肾虚矮小症的机制.方法:30只肾虚矮小症雄鼠随机分为模型组、模型+艾灸运动综合组、模型+右归丸组,每组10只,另取10只正常雄鼠作对照.造模和干预同时进行,共21 d.结果:在肾虚矮小症造模同时予运动和艾灸综合干预,大鼠成骨细胞增多活跃,骨小梁厚度增加,血清T水平显著提升,血清钙、磷表达趋于正常.此外,该综合方案在改善睾丸酮、股骨长及提高血清磷多项指标上优于中药右归丸的干预治疗.结论:艾灸和运动综合方案可较好地改善骨的细胞形态学,从而改善和促进肾虚矮小症雄鼠的生长发育.这种功效似与调整血清睾丸酮、雌二醇、血清钙、磷等优化骨生长的微环境有关.     

注射用头孢米诺在4种输液中的稳定性评价

目的：评价头孢米诺在乳酸钠林格、复方氯化钠、碳酸氢钠、甘露醇注射液中的稳定性。方法：用紫外分光光度法测定配伍液中头孢米诺的含量，并测定不同时间的pH值、含量，观察物理变化。结果：4种配伍液24h内pH值无明显变化。除碳酸氢钠组24h变为黄色外．其他均无外观改变。25℃时头孢米诺在碳酸氢钠注射液中8h含量92．88%．24h含量〈90％，且光谱发生明显改变．其他组24h含量均〉90％。结论：头孢米诺可与乳酸钠林格、复方氯化钠、甘露醇、碳酸氢钠注射液配伍。