孕产妇住院期间的健康教育

本文探讨通过口头讲解与书面指导相结合,计划教育与灵活教育相结合的方式进行孕产妇住院期间的健康教育,其目的 是降低并发症,提高孕产妇的自我保健力,促进其及早康复,提高母子的生命质量.     

Postcoital administration of asoprisnil inhibited embryo implantation and disturbed ultrastructure of endometrium in implantation window in mice

Asoprisnil, a member of the selective progesterone receptor modulators, exerts high progesterone receptor selectivity, endometrial targeted advantages and significant anti-implantation effect in rats. The purpose of this study was to confirm the anti-implantation effect of asoprisil, investigate the ultrastructural changes of the peri-implantation endometrium in mice and explore the effect of asoprisnil on endometrial receptivity and its targeted contraceptive proficiency. Post-coitus mice were administered with different dosages (0.2, 0.1, 0.05 mg·g -1 ·day -1 ) of asoprisnil from day 1 of pregnancy to day 3. Then 3 animals in each group were killed on day 5 of pregnancy, and uteri were collected to examine the ultrastructural changes of endometria under a transmission electron microscope (TEM). A total of 80 animals were sacrificed on day 8 of pregnancy, and the uterine horns were examined for the presence or absence of nidation sites and the number of implantation embryos. The results showed that the implantation rate and the average number of implantation embryos in asoprisnil groups were statistically significantly decreased as compared with the vehicle control group (P<0.05). The TEM results revealed that, in vehicle control group, the tight junction between the luminal epithelia cells was short and straight, the gap was wide; the luminal epithelia cells were covered with plenty of short, clavate and neatly arranged microvilli; the endometril stromal cells were large with plenty of cytoplasm, and showed significant decidual change; there was more than one nucleus in stromal cells, and the karyotheca was integrity. In low dosage and high dosage asoprisnil groups, the tight junction was longer and more curve than in the vehicle control group; microvilli were uneven and asymmetrically distributed in luminal epithelia; the stromal cells were small and the decidual change was not significant; there were karyopyknosis and karyolysis in stromal cells; there were abnormal thick-wall vessels in the endometrium. It was suggested that asoprisnil changed the ultrastructure of the endometrium in implantation window, disturbed the endometrial receptivity and finally resulted in embryo implantation failure.     

CGMS与CSⅡ泵联合在初发2型糖尿病中治疗意义

采用自身前、后对照，对16例初发的2型糖尿病予胰岛素泵输注控制血糖，同时使用CGMS评估。结果：与治疗前相比明显降低（P〈0．01）；血糖漂移的幅度明显降低。结论：CGMS与CSⅡ联合应用能更有效的血糖控制。     

肾手术病人围手术期的健康教育

目的：不同阶段实施健康教育是否能促进肾手术病人的早日康复。方法：将60例手术病人随机分为A、B、C三组，采取术前、术后及术前加术后实施健康教育，观其术后下床活动时间、肛门排气时间，住院天数及肺部感染情况，并进行比较。结果：术前加术后实施健康教育组效果最佳，结论：适时地对肾手术病人进行健康教育和加强护理指导，能充分调动病人的主观能动性，积极配合治疗，对促进病人康复有重要作用。     

2003～2006年南宁市食源性疾病暴发情况分析

目的探讨南宁市食源性疾病暴发的流行特征,为建立起严密的预防机制提供更科学可靠的依据。方法对2003～2006年南宁市传染病疫情报告及食物中毒调查报告资料进行分析。结果2003～2006年南宁市食源性疾病暴发200起,发病3580人,死亡12人。暴发规模平均18人/次(范围2～322人)。暴发以夏秋季多见,51.00%的事件发生在家庭,54.86%的病例集聚在学校食堂。由微生物引发的病例占总数56.98%;在化学物中,有机磷农药的危害及影响最大。动物类食品是暴发事件的主流食品。另外,41.0%的食源性疾病暴发未能查明病因。结论不断完善食源性疾病的监测网络并提高其效能,加强卫生监督管理,筑建严密的食源性疾病监控平台。     

绝经后阴道出血210例临床及病理原因分析

目的探讨绝经后妇女阴道出血的原因。方法对绝经后1年以上阴道出血的210例患者行宫颈刮片脱落细胞检查、宫颈液基细胞学检查、阴道镜检查、子宫内膜活检及宫腔镜检查,分析阴道出血原因以及与恶性肿瘤的关系。结果 210例中生殖器炎症占49.05%,功能性子宫出血占26.19%,恶性肿瘤占10%,其他良性病变占14.76%。结论引起绝经后阴道出血最多的原因是生殖器炎症及功能性子宫出血,但随着年龄增加,绝经时间越长,阴道出血恶性肿瘤的发病率明显增多。     

高频振荡通气救治新生儿呼吸窘迫综合征的观察研究

目的 观察高频振荡通气治疗新生儿呼吸窘迫综合征(NRDS)的疗效.方法 分别用高频振荡通气(HFOV)和常频机械通气(CMV)治疗NRDS新生儿,比较治疗前后血气分析指标、机械通气时间、住院时间、治愈率情况.结果 HFOV组患儿在治疗后6 h、12 h氧浓度(FiO2)、二氧化碳分压(PaCO2)明显下降,氧分压(PaO2)、PaO2/FiO2比值上升明显升高,与CMV对比差异有统计学性意义(P＜0.05);HFOV组机械通气时间、住院时间缩短,治愈率增加,与CMV对比差异有统计学性意义(P＜0.05).结论 高频振荡通气能改善新生儿呼吸窘迫综合征的肺氧合功能,减少并发症,缩短住院时间,降低病死率,较常频机械通气使用更为安全.     

利拉鲁肽治疗12例2型糖尿病合并肥胖患者临床分析

目的分析肠促胰岛素中的胰高血糖素样肽-1(glucagon-like peptide1,GLP-1)类似物利拉鲁肽治疗肥胖2型糖尿病患者的临床疗效。方法选取12例2型糖尿病合并肥胖患者,给予利拉鲁肽治疗,根据血糖监测水平调整治疗方案,24周后比较体重指数、腰围、空腹血糖、糖化血红蛋白变化。结果 12例患者均能耐受利那鲁肽,且体重指数、腰围、空腹血糖、糖化血红蛋白与治疗前比较,均有明显改善,差异有统计学意义(P0.05)。结论利拉鲁肽可有效控制血糖,减轻患者体重,不增加低血糖风险。     

生物共振治疗仪对150例变态反应性疾病患者过敏原检测结果分析

目的：探讨变态反应性疾病与过敏原的关系,了解德国BICOM-2000治疗仪在诊断过敏性疾病的价值,为临床诊疗提供理论依据。方法：应用德国BICOM-2000治疗仪对150例变态反应性疾病患者行过敏原检测,同时随机抽取其中的50例患者行免疫印迹法检测作为对照组,进行相关统计学分析。结果：1.150例患者过敏原检测结果：粉尘螨最高68例（45.33%）,依次为蔬菜类56（37.33%）,谷类46例（30.66%）,花草类植物43例（28.33%）,调味品35例（23.33%）,肉类33例（22.00%）,工业毒物、牛奶分别为33例（22.00%）,霉菌26例（17.33%）,鱼类混合物Ⅱ23（15.33%）,水果21（14.00%）,蛋白和蛋黄19例（12.66%）等。2.吸入组以粉尘螨为主,食入组以牛羊肉、小麦、鱼类混合物Ⅱ、牛奶、蛋白和蛋黄、西红柿为主。3.两种检测方法粉尘螨、鱼类混合物Ⅱ、霉菌检出率有统计学差异（P〈0.05）。结论：两种方法在检测过敏原方面存在一定差异,应根据患者的实际情况进行过敏原的检测,最好结合体内、体外试验共同评价。