CBCT分析上颌后牙根折对上颌窦底黏膜的影响

应用锥形束CT(CBCT)分析上颌后牙根折对上颌窦黏膜的影响,并对上颌窦黏膜炎症反应进行相关性研究.随机选取经CBCT扫描并诊断为一侧根折另一侧无症状的患者50例为实验组,对窦底黏膜厚度,根尖到上颌窦底的距离进行测量,并对数据进行统计学分析.实验组患者根折侧上颌窦黏膜存在增厚改变的发生率为88％,对照侧为2％,差异有统计学意义(P＜0.05).在实验组中,根折伴根尖周炎组、根折伴牙周炎组、无其他症状根折组的黏膜厚度,差异无统计学意义.根折患者上颌窦底黏膜容易发生增厚样改变.根折后常伴有根尖周炎、牙周炎等症状,但不同临床症状对上颌窦黏膜厚度影响无差异性.根折牙根距上颌窦底越近,可能更容易对上颌窦黏膜产生影响.     

BiPAP无创通气治疗妊娠并发急性左心衰竭28例疗效观察

目的评价双水平正压无创通气(BiPAP)救治妊娠并发急性左心衰的临床疗效。方法将我院的56例妊娠并发急性左心衰患者随机分成两组,治疗组28例(A组),在常规药物抗心衰治疗基础上联用BiPAP呼吸机面罩正压通气治疗,测定动脉血氧分压,观察血压、心率、呼吸及临床症状,并进行相关分析。对照组28例(B组)常规药物抗心衰治疗。结果治疗组在治疗后1h、3h,心率、呼吸、动脉血氧分压、平均动脉压的改善明显优于对照组(P<0.05),治疗显效率为50.00%,总有效率为82.14%,均明显高于对照组(P<0.05)。结论妊娠并发急性左心衰患者在常规药物抗心衰治疗基础上联用BiPAP呼吸机面罩正压通气治疗较单纯常规药物抗心衰治疗对患者心率、呼吸、血氧的改善明显且治疗效果显著,值得临床推广运用。     

基于脑-肢协同调控模式探讨LF-rTMS联合推拿对脑卒中后肢体运动功能障碍的影响

目的:观察低频重复经颅磁刺激(Low Frequency Repetitive Transcranial Magnetic Stimulation,LF-rTMS)联合推拿治疗对脑卒中后肢体运动功能障碍的疗效.方法:将80例符合纳入标准的脑卒中后肢体运动功能障碍患者采用随机数字表分成治疗组和对照组,两组均予以常规药物治...     

MEF2A基因第11号外显子突变的检测及其基因结构分析

目的检测我国汉族人群中MEF2A基因第11号外显子区的突变,分析MEF2A特异性突变的基因结构和遗传学意义。方法用PER-SSCP和／或PCR产物直接测序法对536例冠状动脉粥样硬化性心脏病阳性病例、232例冠状动脉粥样硬化性心脏病阴性对照及232例健康体检者的MEF2A基因第11号外显子区进行突变检测,用质粒克隆测序法对各突变位点作进一步验证。结果在冠状动脉粥样硬化性心脏病阳性病例组发现一例MEF2A 21碱基的特异性突变。另外还发现二种罕见的突变类型。结论MEF2A基因第11号外显子区存在多种罕见的突变类型,基因结构分析显示MEF2A基因21碱基特异性突变有多种形成模式。     

2005年至2008年全国HLA低分辨基因分型检测室间质量评价结果分析

Objective National external quality assessment (EQA) results from 2005 to 2008 for HLA class Ⅰ (A, B) and class Ⅱ (DRB1) low-resolution DNA typing were summarized with the goal of exploring strategies to assure and improve HLA DNA typing performance in clinical testing. Methods HLA allele results from the four consecutive years EQA events were analysed. Different kinds of errors were described and classified, and the possible causes were discussed. Results Participant laboratories were increasing in the four consecutive years with the number of 22, 28, 47 and 61 in 2005, 2006, 2007 and 2008,respectively. 2 844 HLA DNA typings were returned from the participants during the 4 years EQA surveys, and overall 30 errors (1.05%) were identified. These 30 errors were classified into two major types of errors including 25 technical genotyping errors and 5 human errors. The proportion of laboratory participants which made mistakes was 13. 6%, 10. 7%, 10. 6% and 16.4% in 2005, 2006, 2007 and 2008, respectively. Conclusions Above 10% of participant laboratories exhibited errors in the four consecutive years HLA molecular typing EQA surveys. Relevant important attentions should be greatly paid to clinical HLA molecular typing test.     

2005年至2008年全国HLA低分辨基因分型检测室间质量评价结果分析

Objective National external quality assessment (EQA) results from 2005 to 2008 for HLA class Ⅰ (A, B) and class Ⅱ (DRB1) low-resolution DNA typing were summarized with the goal of exploring strategies to assure and improve HLA DNA typing performance in clinical testing. Methods HLA allele results from the four consecutive years EQA events were analysed. Different kinds of errors were described and classified, and the possible causes were discussed. Results Participant laboratories were increasing in the four consecutive years with the number of 22, 28, 47 and 61 in 2005, 2006, 2007 and 2008,respectively. 2 844 HLA DNA typings were returned from the participants during the 4 years EQA surveys, and overall 30 errors (1.05%) were identified. These 30 errors were classified into two major types of errors including 25 technical genotyping errors and 5 human errors. The proportion of laboratory participants which made mistakes was 13. 6%, 10. 7%, 10. 6% and 16.4% in 2005, 2006, 2007 and 2008, respectively. Conclusions Above 10% of participant laboratories exhibited errors in the four consecutive years HLA molecular typing EQA surveys. Relevant important attentions should be greatly paid to clinical HLA molecular typing test.     

2005年至2008年全国HLA低分辨基因分型检测室间质量评价结果分析

Objective National external quality assessment (EQA) results from 2005 to 2008 for HLA class Ⅰ (A, B) and class Ⅱ (DRB1) low-resolution DNA typing were summarized with the goal of exploring strategies to assure and improve HLA DNA typing performance in clinical testing. Methods HLA allele results from the four consecutive years EQA events were analysed. Different kinds of errors were described and classified, and the possible causes were discussed. Results Participant laboratories were increasing in the four consecutive years with the number of 22, 28, 47 and 61 in 2005, 2006, 2007 and 2008,respectively. 2 844 HLA DNA typings were returned from the participants during the 4 years EQA surveys, and overall 30 errors (1.05%) were identified. These 30 errors were classified into two major types of errors including 25 technical genotyping errors and 5 human errors. The proportion of laboratory participants which made mistakes was 13. 6%, 10. 7%, 10. 6% and 16.4% in 2005, 2006, 2007 and 2008, respectively. Conclusions Above 10% of participant laboratories exhibited errors in the four consecutive years HLA molecular typing EQA surveys. Relevant important attentions should be greatly paid to clinical HLA molecular typing test.     

基于奥马哈系统的移动医疗App用于神经根型颈椎病患者健康管理

目的探讨基于奥马哈系统的移动医疗App用于神经根型颈椎病患者健康管理的效果。方法将64例神经根型颈椎病患者随机分为对照组(n=31)和观察组(n=33)。对照组接受颈椎病常规护理,观察组在常规护理的基础上使用基于奥马哈系统设计的App进行延续护理干预。于出院前及出院6个月后,评估比较两组自我管理能力、自我效能及颈椎功能恢复情况。结果干预后,观察组自我管理行为和自我效能得分显著高于对照组,而颈椎功能障碍指数评分显著低于对照组(P0.05,P0.01)。结论基于奥马哈系统的移动医疗App用于神经根型颈椎病患者出院后自我健康管理,有利于提高患者自我健康管理能力和自我效能,从而改善其颈椎功能。     

热毒宁注射液治疗急性上呼吸道感染30例临床分析

目的探讨热毒宁注射液对上呼吸道感染的疗效和安全性。方法2006年12月～2007年2月在我科门诊用热毒宁注射液治疗急性上呼吸道感染患者30例,观察治疗前后症状体征的变化以及外周血常规、尿常规、大便常规、肝功能、肾功能、心电图的变化。结果痊愈21例,显效6例,好转2例,脱落1例,总有效率为96.7%。结论热毒宁注射液对上呼吸道感染的疗效好,安全性高。