灌肠类肉制品卫生质量调查分析

灌肠类肉制品食用方便,深受消费者的喜爱,其卫生质量的优劣,直接关系到广大消费者的食用安全和身体健康。为了解灌肠类肉制品的卫生质量状况,我们开展了这项调查工作,为加强对灌肠类肉制品卫生监督,提供了科学依据。1 样品来源与方法 从当地肉制品厂和市售灌肠类制品经销点随机抽取被检样品108份,其中香肠26份,肉肠24份,红肠16份,火腿肠30份,香肚12份,按最新检验方法进行,并按GB 2725.1—94和GB10147—88进行评价。将样品按感官指标检查,分为优、次、劣质品三个等级。     

再次经尿道前列腺切除患者前列腺组织学特征及其临床意义

目的:探讨再次经尿道前列腺切除术(TURP)患者前列腺组织的病理组织学特征及其临床意义。方法:选取再次TURP手术的50例患者前后两次手术标本(再次TURP组)和50例仅有一次手术患者的标本(对照组)。采用免疫组织化学S-P法检测前列腺组织中CD34、VEGF、AR的表达,计算微血管密度(MVD)值及VEGF、AR指数,并对再次TURP组首次标本和对照组标本、再次TURP组两次手术标本分别进行比较及统计学分析。结果:VEGF、AR在所有标本中均有表达。再次TURP组首次标本中MVD值、VEGF指数、AR指数分别为:35.83±20.92、7.55±2.72、6.17±1.86,再次手术的标本为:32.16±16.65、7.06±2.36、6.99±2.44;对照组为:20.56±6.99、4.28±2.62、4.16±1.34。再次TURP组首次标本MVD值、AR、VEGF指数均高于对照组,两组差异有统计学意义(P<0.05);而再次TURP组前后两次手术标本间各指标差异无统计学意义(P>0.05)。相关分析发现,AR指数和VEGF指数、VEGF指数和MVD值、AR指数和MVD值之间均存在正相关,相关系数(r)分别为:0.650、0.705、0.525(P<0.05)。结论:BPH患者前列腺组织中高MVD值及AR、VEGF的高表达是导致其TURP术后复发及再次手术的重要原因之一,可作为判断术后复发的危险因素及采取针对性预防措施的指标。     

低温春化对菘蓝体内碳氮代谢的影响

目的:探索菘蓝在低温春化过程中碳、氮代谢的变化.方法:以云南菘蓝和北京菘蓝6叶龄幼苗为实验材料,4℃条件下进行低温处理25 d,并测定碳氮代谢相关指标.结果:低温春化使菘蓝体内的可溶性糖、还原糖、可溶性蛋白质含量呈上升趋势,春化完成时达到最大值,然而低温春化使菘蓝体内的淀粉、全氮含量呈下降趋势,春化完成时降至最低.结论:低温春化过程中,高的C/N值才能促进菘蓝春化.     

杏花雨注射液对荷瘤小鼠血清IL-2、TNF-α水平的影响

目的观察杏花雨注射液对肝癌H22模型小鼠血清中IL-2及TNF-α水平的影响。方法将接种肝癌H22瘤细胞的昆明鼠随机分为5组,即模型对照组、杏花雨注射液低剂量组、杏花雨注射液中剂量组、杏花雨注射液高剂量组及环磷酰胺阳性对照组。于接种后24h各组开始给药,连续7d。末次给药后24h,内眦取血测定血清IL-2及TNF-α浓度。结果杏花雨注射液中、高剂量组血清IL-2浓度明显高于模型对照组（P〈0.05）;杏花雨注射液中、高剂量组血清TNF-α浓度明显高于模型对照组（P〈0.01）。结论杏花雨注射液能提高荷瘤小鼠血清IL-2及TNF-α水平。     

小儿泌尿系感染53例临床分析

目的 探讨小儿泌尿系感染治疗.方法 回顾性分析53例小儿泌尿系感染患者的临床资料.结果 53例病人中其中3例存在泌尿系先天性畸形、5例合并泌尿系结石,去除原发病后泌尿系感染痊愈,余根据病情变化及实验室结果及时调整用药.其中35例应用三代头孢菌素,患儿中有10例头孢菌素过敏改用氨曲南.静脉滴注疗程为710d症状消失.药物...     

放射医学在特大地震伤员诊治中的应用价值

目的探讨放射医学在特大地震伤员诊治中的应用价值。方法对汶川特大地震收治的192例伤员中的155例伤员的影像及临床资料进行分析。结果155例中135例行X线平片检查,43例行CT检查,同时行X线平片、CT检查23例,共儿6例发现骨折。单发骨折62例,多发骨折54例,开放性骨折11例,闭合性骨折105例,关节脱住3例,其中32例有多部位损伤。颅骨骨折3例,脊柱压缩性骨折7例,爆裂样骨折3例,骨盆骨折13例,肋骨、锁骨骨折26例,肩胛骨骨折2例,四肢骨折73例,肺挫裂伤5例,气胸及液气胸8例,颅内硬膜外血肿2例,脑挫裂伤2例,脾挫裂伤1例,骨折以四肢骨折多见。结论X线、CT检查在地震伤员诊断、治疗方案的选择及预后评估中具有重要价值。     

抗HLA和抗MICA抗体的表达对移植肾功能和急性排斥反应的预示作用

Objective To investigate the prediction of anti-human leukocyte antigen antibodies (HLA) and anti-major histocompatibility complex class I-related chain A antibodies (MICA) to the development of acute rejection (AR) and kidney allograft function. Methods Forty-one kidney transplant patients were prospectively tested for anti-HLA and anti-MICA. Thirty-seven patients were screened using Luminex/single-antigen beads to determine the HLA and MICA-specific antibody levels at 0,30,90, 180,360,720 and 1080 days post-transplantation. The patients and donors of HLA and MICA allele typing were determined by PCR-SSOP, and donor specific antibody (DSA) and non-donor specific antibody (NDSA) were identified.Simultaneously,their serum creatinine (SCr) levels and clinical data were analyzed. Results Nine patients (21.95 % ,9/41 ) had pre-existing anti-HLA and(or) anti-MICA, including 6 cases of anti-MICA,2 cases of anti-HLA, and one case of anti-MICA and anti-HLA. Nine patients had pre-existing DSA and NDSA. In the 37 patients, 6 patients (16.2% ) developed de novo anti-HLA, and 3 (8.1%) developed de novo antiMICA. In patients positive for de novo anti-HLA, the titer of antibody was gradually increased during the follow-up of three years. Four patients out of 9 patients with pre-existing antibodies were suffered from AR (44.4%); In 6 patients positive for de novo anti-HLA,three cases (50.0%) were suffered from AR; In three patients positive for de novo anti-MICA,no AR occurred (P＜0.05). In two patients positive for DSA of HLAⅡ antibody detected at the third and seventh day after transplantation, the renal grafts were renovecd due to rejection. The Scr levels in patients positive for pre-existing MICA with AR were higher than in those positive for pre-existing MICA without AR at each scheduled time point during the follow-up period (P＜0.05). The Scr levels in patients negative for antibodies pre-transplantation and having AR were higher than in those having no AR at each scheduled time point during the follow-up period (P＜0. 01 ). The Scr levels in patients positive for de novo HLA and MICA and having AR one month following transplantation were higher than in those negative for antibodies and having no AR (P＜0.01 ). Conclusion Pre-existing and de novo anti-HLA were the irnportant factors for the development of AR, but the mismatch of HLA and MICA alleles in donors and patients was primary causes for generation of de novo antibodies.     

庞学丰教授治疗结节性红斑经验

吾师庞学丰,教授,主任医师,硕士研究生导师,现为中华中医药学会风湿病分会常务委员、中国中西医结合学会风湿类疾病专业委员会委员、中国中西医结合防治风湿病联盟常务委员、广西中西医结合学会风湿病分会主任委员,长期从事风湿病的临床、科研与教学工作,学识渊博,经验丰富,对于结节性红斑的治疗,审证细微,用药巧妙,疗效颇佳。兹将其经验介绍如下。     

医学病理实验室建设与管理的做法和体会

医学院校及其教学医院的病理实验室,是医疗、教学和科研工作的重要组成部分。在病理实验室的建设和管理上,实行系统管理规程:建立规范化管理的机制,强化病理实验人员的整体素质培养,提高病理实验人员的技术水平和操作水平,有效地保证病理实验的正常开展,为教学与科研提供保障和优质的服务。