肠外肠内营养与谷氨酰胺的补充

肠道作为人体的消化器官，在维持机体正常营养中起着极其重要的作用。肠粘膜面积约１０ｍ２，在某些情况下是细菌及毒素侵入人体的危险通道。在创伤、手术、放疗、化疗、严重感染、重症胰腺炎等应激状态下，可继发肠粘膜屏障损害，３０％发生细菌和毒素移位，其中５％可发...     

后腹腔镜治疗肾上腺肿瘤65例报告

[目的]总结后腹膜腔镜技术在肾上腺肿瘤切除术的经验. [方法]采用后腹膜腔镜技术切除肾上腺肿瘤65例,男28例,女37例,年龄21～67岁,平均37岁,左侧30例,右侧35例,其中原发性醛固酮腺瘤29例,皮质醇脂瘤18例,嗜铭细胞瘤6例,神经节细胞瘤3例,无功能性腺瘤9例. [结果]该组58例手术均取得成功,手术时间35-200 rain,..术中失血80～220ml,术中、术后均未输血,无明显并发症,另有7例改开放手术.[结论]后腹膜腔镜手术切除肾上腺入路符合泌尿外科医师习惯,手术效果好,具有损伤小,痛苦小,患者恢复快、并发症少等优点,是一种安全有效的治疗方法,但掌握需要一定的学习曲线. 上腺肿瘤65例,男28例,女37例,年龄21～67岁,平均37岁,左侧30例,右侧35例,其中原发性醛固酮腺瘤29例,皮质醇脂瘤18例,嗜铭细胞瘤6例,神经节细胞瘤3例,无功能性腺瘤9例. [结果]该组58例手术均取得成功,手术时间35-200 min,术中失血80～220ml,术中、术后均未输血,无明显并发症,另有7例改开放手术.[结论]后腹膜腔镜手术切除肾上腺入路符合泌尿外科医师习惯,手术效果好,具有损伤小,痛苦 ,     

异种移植模型有助于儿童抗癌

急性成淋巴细胞白血病（ALL）是儿童中最常见的癌症，尽管用目前的治疗方案，已经取得明显的疗效，但对治疗的抵抗性仍然是癌症研究人员竭力想搞明白的一个难题。     

胃肠道平滑肌肿瘤ras癌基因产物P21表达及其与临床病理的关系

胃肠道平滑肌肿瘤ｒａｓ癌基因产物Ｐ２１表达及其与临床病理的关系蔡建辉，蒋贻康，张玉印，张祥宏，吕贵华我们应用流式细胞术对胃肠道平滑肌肿瘤（ＧＩＳＭＴ）的ｒａｓＰ２１表达进行定量分析。旨在结合组织学观察，探讨判断肿瘤良、恶性及病人预后的新途径。一、材料...     

严重老年胸伤患者临床流行病学特征与救治结局分析

Objective To further improve level of severe chest trauma care in the elderly pa-tients. Methods A retrospective study was done on data of 148 elderly patients (≥65 years with se-vere chest trauma (AIS≥3 points) (elderly group) treated in Chongqing Emergency Medical Center from June 1995 to May 2005. A total of 1669 patients at age less than 65 years and with AIS≥3 points were set as control group in the same research period (control group). Results The main injury mechanism was blunt trauma, which aceouted for 83.8% (124/148) in elderly group, higher than 69.3% (1 157/ 1 669) in control group (P < 0. 01). The injury causes were mainly traffic accidents, slip and fall from a height. Traffic accidents and slip accounted for 66.2% (98/148) and 14.9% (22/148) respectively, which was significantly higher than 50.6% (845/1 669) and 3.1% (52/1 669) respectively in control group (P < 0. 01). There was no statistical difference upon ISS, RTS, GCS and prehospital time between both groups (all P value > 0.05). The fatality rate and indicence rate of complication in the elerly group were 15.5% (23/148) and 25.7% (38/148), which was significantly higher than 6.5% (108/1 669) and 10.4% (174/1 669) respectively in control group (P <0.01). The fatality rate in elderly group with complications was significantly higher than that in control group (51.7% vs 26.7%) (P < 0.01), while those without complications showed no statistical difference between two groups (6.7% :3.5%) (P >0. 05). Conclusions The patient' s age and complications are relative independent factors to es-timate the trauma care outcome. To raise risk awareness and strengthen the management of complications and supportive treatments for organ function are key to improve survival rate of the elderly patients with se-vere chest trauma.     

增生性玻璃体视网膜病变增生膜中survivin基因的表达

目的：探讨凋亡抑制基因survivin在增生性玻璃体视网膜病变(PVR)增生膜中的表达．方法：玻璃体手术中取出的10例PVR患的增生膜，应用免疫组织化学方法(SABC法)检测增生膜中survivin基因的表达．结果：10例增生膜中，6例表达阳性．阳性染色位于膜上大部分细胞的胞质内及细胞外基质中。结论：Survivin基因的异常表达引起细胞的凋亡抑制，在PVR的发生中起一定作用。     

涂碳式聚氯乙烯膜电极测定盐酸苯海拉明片含量

目的　建立用涂碳式聚氯乙烯膜盐酸苯海拉明电极测定盐酸苯海拉明片含量的方法。方法　利用该电极对盐酸苯海拉明的响应 ,测定盐酸苯海拉明片含量。结果　平均回收率为 99 6 % ,RSD为 1 87%响应范围为1 0× 10 2 ～ 2 4× 10 5mol/L ,检测限为 1 6× 10 5mol/L。结论　涂碳式聚氯乙烯膜电极法可简便、快速、准确地检测片剂中盐酸苯海拉明的含量。     

人癌的卟啉光疗

血卟啉症(Porphyrias)为一组疾病,包括皮肤中天然卟啉累积过多,而引起急性光敏作用的疾病。诸如红细胞生成性原卟啉症(Erythropoietic protoporphyria),其特点是具有高水平的原卟啉;而皮肤、肝脏的血卟啉症则可引起过量的尿卟啉(Uropor-phyrin)。人体的光敏性也可因使用卟啉所引     

血清紫色反应在肺癌诊断中的应用价值

据Nixon氏报告,96%未经治疗的恶性肿瘤患者血清与Ehrlich氏试剂一起温育后所呈现的紫色反应较正常人或非恶性肿瘤患者明显加深,并认为此反应可能是血中色氨酸或粘蛋白部份有关物质与Ehrli ch试剂反应的结果。芦妙如氏曾检测250例肿瘤患者血清紫色反应,认为该反应对肿瘤早期诊断具有一定价值。