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31.
Objective To evaluate the effect of intensity-modulated radiation therapy(IMRT) on parotid function in nasopharyngeal carcinoma(NPC). Methods Eighty-three NPC patients received prima-ry IMRT between 2001 and 2003. Xerostomia before radiotherapy, at the end of radiotherapy, at 6-month, 1-,2-,3-,4- and 5-year after radiotherapy were investigated, respectively. The relation between xerostomia and parotid dose distribution was analyzed. Results Of all the patients,4,31,31 and 17 had stage Ⅰ,Ⅱ,Ⅲ and ⅣA disease, respectively. Sixteen patients received chemo-radiotherapy. The median followed-up time was 65 months. The 5-year local control and regional control rate were 96% and 95% ,respectively. The 5-year overall survival rate was 80%. The mild xerostomia rate at the seven time points was 42%, 51%, 71%, 77%, 58%, 38% and 26%. The corresponding moderate xerostomia rate was 52%, 53%, 21%,8%, 3%, 2% and 2%, respectively. No serious xerostomia was observed. The mean dose of the bilateral parotid glands was 34.34 Gy. Xerostomia at 6-month after radiotherapy was positively correlated with the mean dose of the parotid glands, and D50 was the independent factor in predicting the xerostomia. Parotid function was well protected when the mean dose and D50 were no more than 33 Gy and 29 Gy,respectively. Conclusions IMRT can improve the local-regional control of NPC and protect the parotid glands from radiation-induced in-jury.  相似文献   
32.
Objective To evaluate the effect of intensity-modulated radiation therapy(IMRT) on parotid function in nasopharyngeal carcinoma(NPC). Methods Eighty-three NPC patients received prima-ry IMRT between 2001 and 2003. Xerostomia before radiotherapy, at the end of radiotherapy, at 6-month, 1-,2-,3-,4- and 5-year after radiotherapy were investigated, respectively. The relation between xerostomia and parotid dose distribution was analyzed. Results Of all the patients,4,31,31 and 17 had stage Ⅰ,Ⅱ,Ⅲ and ⅣA disease, respectively. Sixteen patients received chemo-radiotherapy. The median followed-up time was 65 months. The 5-year local control and regional control rate were 96% and 95% ,respectively. The 5-year overall survival rate was 80%. The mild xerostomia rate at the seven time points was 42%, 51%, 71%, 77%, 58%, 38% and 26%. The corresponding moderate xerostomia rate was 52%, 53%, 21%,8%, 3%, 2% and 2%, respectively. No serious xerostomia was observed. The mean dose of the bilateral parotid glands was 34.34 Gy. Xerostomia at 6-month after radiotherapy was positively correlated with the mean dose of the parotid glands, and D50 was the independent factor in predicting the xerostomia. Parotid function was well protected when the mean dose and D50 were no more than 33 Gy and 29 Gy,respectively. Conclusions IMRT can improve the local-regional control of NPC and protect the parotid glands from radiation-induced in-jury.  相似文献   
33.
1924年Berger和Luc首先报道了嗅神经母细胞瘤[1].这是一种罕见的恶性肿瘤,发病率0.4/百万[2],占鼻腔恶性肿瘤5%~13.2%[3-4].目前普遍认为其起源于嗅上皮的原始基底细胞,属神经内分泌来源肿瘤.笔者对本院收治的54例嗅神经母细胞瘤患者资料进行回顾性分析.  相似文献   
34.
云南元江芦荟花营养成分分析及评价   总被引:5,自引:0,他引:5  
目的:为了解芦荟花的营养成分及价值,对云南元江芦荟花和库拉索芦荟花进行营养成分分析及营养评价。方法:采用公认的国家标准分析方法测定两种芦荟花中营养成分。结果:元江芦荟花和库拉索芦荟花富含维生素C,分别高达105、82mg/100g。结论:芦荟花具有较大的开发利用价值,测定结果为云南野生食物资源的开发及推广运用提供科学参考依据。  相似文献   
35.
子宫颈癌放射治疗的几个热点问题   总被引:2,自引:0,他引:2  
吴少雄 《广东医学》2004,25(2):120-121
放射治疗在子宫颈癌治疗中一直占有重要地位,大约80%的宫颈癌患者需要放射治疗作为单独治疗或综合治疗手段之一。腔内近距离治疗(ICBT)结合体外照射(EBRT)是最普遍使用的放射疗法,适合于治疗各个临床期别的子宫颈癌,但疗效并不理想,临床I,Ⅱ期患者放疗后的5年生存率约为65%~85%,Ⅲ,Ⅳ期者为20%~50%。近年来,对子宫  相似文献   
36.
目的探讨和总结对晚期癌症患者进行CIK细胞临床静脉输注的护理经验。方法观察接受治疗的患者体温、呼吸、血压等生命体征的变化情况及有无过敏反应。结果收治患者中除个别患者有一过性发热、头痛、呼吸加快的症状外,绝大多数患者无特殊反应,经处理后,症状可在短期内消失。结论应用CIK细胞静脉输注治疗癌症患者是比较安全的,所采取的护理方法具有简单和实用性。  相似文献   
37.
鼻咽癌常规放射治疗后颅底推量的临床价值评估   总被引:1,自引:0,他引:1  
[目的]探讨颅底受累鼻咽癌常规放疗后颅底推量的临床价值。[方法]2000年1月至2001年12月经病理学确诊、影像学证实有颅底骨质破坏、常规放疗剂量为68~72Gy的初治鼻咽癌患者共497例,其中,120例于放疗结束时即予双侧颅底野推量6~12Gy(推量组),377例无颅底推量(无推量组)。局控率、总生存率及神经系统放射性并发症发生率为主要评价指标。[结果]中位随访时间60.7个月(5.1~109.5个月)。两组5年鼻咽控制率、颅底颅内控制率、总生存率和无颅神经损伤发生率比较均无显著性差异,但推量组的5年无颞叶坏死发生率明显低于无推量组(71.4%vs91.1%,P〈0.001)。以蝶窦、海绵窦、筛窦侵犯和T3、T4期作为5个亚组进行分析,结果显示颅底推量均不能提高各亚组的颅底颅内控制率和总生存率。[结论]常规放疗后采用颅底野对颅底受累的鼻咽癌患者推量的方法未能获得局控率和总生存率的改善,但可使放射性颞叶坏死发生率明显增加。  相似文献   
38.
Objective To evaluate the effect of intensity-modulated radiation therapy(IMRT) on parotid function in nasopharyngeal carcinoma(NPC). Methods Eighty-three NPC patients received prima-ry IMRT between 2001 and 2003. Xerostomia before radiotherapy, at the end of radiotherapy, at 6-month, 1-,2-,3-,4- and 5-year after radiotherapy were investigated, respectively. The relation between xerostomia and parotid dose distribution was analyzed. Results Of all the patients,4,31,31 and 17 had stage Ⅰ,Ⅱ,Ⅲ and ⅣA disease, respectively. Sixteen patients received chemo-radiotherapy. The median followed-up time was 65 months. The 5-year local control and regional control rate were 96% and 95% ,respectively. The 5-year overall survival rate was 80%. The mild xerostomia rate at the seven time points was 42%, 51%, 71%, 77%, 58%, 38% and 26%. The corresponding moderate xerostomia rate was 52%, 53%, 21%,8%, 3%, 2% and 2%, respectively. No serious xerostomia was observed. The mean dose of the bilateral parotid glands was 34.34 Gy. Xerostomia at 6-month after radiotherapy was positively correlated with the mean dose of the parotid glands, and D50 was the independent factor in predicting the xerostomia. Parotid function was well protected when the mean dose and D50 were no more than 33 Gy and 29 Gy,respectively. Conclusions IMRT can improve the local-regional control of NPC and protect the parotid glands from radiation-induced in-jury.  相似文献   
39.
毛冬表(IP)作为鼻咽癌放射治疗增敏剂的临床观察(I)   总被引:6,自引:0,他引:6  
吴少雄  张恩罴 《癌症》1992,(1):56-59
  相似文献   
40.
恶性黑色素瘤是一种产生黑色素的高度恶性肿瘤。1974年上海市恶性黑色素瘤患病率仅为0.41人次/10万。此病多见于四肢及躯干皮肤,但发生于鼻咽部则极为罕见。国内、外曾备报道一例。我科于1987年8月收治一例并行单纯放疗,现报道如下:  相似文献   
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