140例维吾尔族百岁老人下颌骨体表测量的观察

目的：观察下颌骨体有无增龄变化及其相关因素。方法：对１４０例维吾尔族百岁老人采用对一侧下颌骨体表直接测量长度及高度，并进行统计学处理。结果：一侧下颌骨体表长度在８．５ｃｍ～１３．０ｃｍ，高度在１．５ｃｍ～５．０ｃｍ，青年组长度大于百岁组（Ｐ＜０．００１），男性组长、高度大于女性组（Ｐ＜０．０１），有牙颌组长高度大于无牙颌组（Ｐ＜０．０１），正常舌组下颌骨长度大于裂纹舌组（Ｐ＜０．０５），但高度无显著性差异（Ｐ＞０．０５）。结论：下颌骨长高度具有生理变化，同时年龄、性别、有无牙列亦有影响，裂纹舌可能与下颌骨缩小有关。百岁老人有下颌骨体增龄表现     

弹性模量和初始应力对种植体骨界面应力分布影响的三维有限元分析

目的:分析种植体弹性模量与骨界面应力分布的关系。方法:用三维有限元的方法对不同弹性模量种植体在各种载荷下骨界面的应力大小和分布进行分析。结果:种植体周围界面骨组织应力强度随着材料弹性模量的增大而增大。结论:低弹性模量的钛合金材料作为种植材料时具有更好的生物力学相容性。初始应力在分析种植体骨界面应力分布时必须加以考虑。     

Simultaneous flapless implant placement and peri-implant defect correction: an experimental pilot study in dogs

BACKGROUND: Minimally invasive implant surgery allows clinicians to place implants in less time, without extensive flaps, and with less bleeding and postoperative discomfort. The purpose of this study was to evaluate a new surgical technique by which implants are inserted in a deficient alveolar ridge using a flapless technique simultaneously with a peri-implant defect correction that is performed using a subperiosteal tunneling procedure. METHODS: Bilateral, horizontal defects of the alveolar ridge were created in the mandibles of five mongrel dogs. After 3 months of healing, one implant was placed on each side of the mandible by a flapless procedure. The exposed threads of the implant on one side of the mandible were covered with a 1:1 autogenous bone/xenograft mixture using a subperiosteal tunneling technique. Four months later, biopsies of the implant sites were taken and prepared for ground sectioning and analysis. RESULTS: All implants were well osseointegrated with the host bone. All of the peri-implant defects at the test sites were covered with tissue that resembled bone. In all specimens, a mixture of bone, connective tissue, and residual bone particles was observed in the graft area. In the control sites, where no graft was used, none of the exposed threads on any implants were covered with new bone. CONCLUSION: This preliminary report indicates the potential use of a minimally invasive flapless technique as a substitute for a more invasive implant placement and ridge augmentation procedure.     

Brain activation patterns during unilateral premolar occlusion

Objective: To observe the characteristics of brain activation during unilateral premolar occlusion.

Methods: Functional magnetic resonance imaging was collected from 10 healthy volunteers during occlusion of the left first premolar (L1), left second premolar (L2), and right first premolar (R1). The brain activation patterns were analyzed, and the primary sensorimotor cortex, supplementary motor area, insula, thalamus, and prefrontal cortex were chosen as regions of interest.

Results: Single premolar occlusion activated the precentral gyrus, postcentral gyrus, cerebellum, thalamus, frontal lobe, hippocampus, cingulate gyrus, and parietal lobe. The brain areas showing activation during single premolar occlusion were similar to those activated by chewing. The activation pattern of L1 was more similar to that of L2 than R1. No significant left and right hemisphere differences in signal intensity were detected within the regions of interest.

Conclusion: Brain activation patterns from two ipsilateral premolars were more similar than the pattern from a contralateral premolar.     

胶囊粉对可见光固化复合树脂机械性能的影响

目的:改善光固化复合树脂的强度和抛光性能.方法:我们采用悬浮聚合法研制了微胶囊型复合填料粉(MCP),作为光固化改进型(VLC-Ⅱ型)复合树脂的填料.并对其性能进行了测试.结果:在复合树脂中加入15%的胶囊型填料粉,压缩强度可达232.1±9.1MPa,拉伸强度可达48.7±2.3MPa,70000次牙刷磨耗率为0.588%,表面粗糙度为2.8μm.结论:胶囊粉可以显著改善复合树脂的压缩强度,拉伸强度,磨耗及表面抛光性等机械性能.与其它同类产品比较,其机械性能、磨耗性能和表面抛光性能均较优越,且相差显著.     

姜黄素对口腔舌癌细胞增殖与转移能力影响的实验研究

目的 探讨姜黄素对口腔舌癌细胞增殖与转移能力的作用及其作用机制.方法分别以0、5、10、20、30、60、100μmol·L-1姜黄素处理人舌癌细胞SCC-4 24 h,采用MTT法、侵袭实验、流式细胞仪、免疫荧光显微镜分别检测姜黄素对口腔舌癌细胞增殖与转移能力的影响.然后,采用cDNA微陈列芯片技术筛选和实时定鼍RT...     

涎腺腺样囊性癌中p16蛋白,增殖细胞核抗原(PCNA)染色与病理分型、神经侵犯和复发的关系

目的 :探讨涎腺腺样囊性癌中 p16蛋白与PCNA在染色与病理分型、神经侵犯、复发中的关系。 方法 :利用免疫组化SP法 ,对 5例正常涎腺组织和 3 6例涎腺腺样囊性癌组织p16蛋白及PCNA染色进行检测 ,并对患者进行 10年随访观察。结果 :3 6例腺样囊性癌中 ,不同病理分型癌细胞组织中 p16蛋白阳性染色率间差异有统计学意义 (P <0 .0 5 ) ,PCNA阳性染色率间差异无统计学意义 (P >0 .0 5 ) ,有无神经侵犯癌组织中 p16蛋白阳性染色率间差异无统计学意义 (P >0 .0 5 )。有无复发癌组织中p16蛋白阳性染色率间差异有统计学意义 (P <0 .0 5 )。PCNA阳性染色率间差异有统计学意义 (P <0 .0 5 )。结论 :p16基因突变、缺失与腺样囊性癌病理类型有关 ,其表达水平反映肿瘤组织分化程度。p16蛋白及PCNA表达水平可以作为临床评价肿瘤侵袭性和预测复发的指标     

Prevalence and severity of malocclusion in children with cleft lip and/or palate in Hong Kong.

The prevalence and severity of malocclusion among children with cleft lip and palate in Hong Kong has never been assessed or documented. A group of 20 children in the primary or early mixed dentition stages, with clefts of the lip and/or palate were assessed using the Occlusal Index. Results of this preliminary study showed that 92.3 percent of the male and 71.5 percent of the female subjects had severe malocclusion, which implied that comprehensive orthodontic treatment at a later stage would be needed. More than half (69.2% of the male, and 57.1% of the female subjects) had syndrome F, defined as mesial molar relationship, overjet, overbite, posterior crossbite, midline diastema, and midline deviation (Summers, 1966). Therefore malocclusion problems were shown to manifest early in patients with cleft lip and/or palate, and further that it is possible to assess malocclusion prevalence and severity in early stages of dental development.     

正畸弓丝在模拟牙矫治实验中的力学性能测定

本文通过模拟上颌前牙矫治实验，测定了目前国内常用几种弓丝的弹性性能。结果显示不锈钢类弓丝刚度大，其中澳丝刚度最大。镍钛丝和带垂直曲的弓丝刚度小，能提供较持续的矫治力。0．014中国镍钛丝具有超弹性性能，而0．016中国镍钛丝在0～250g范围内未显示出超弹性。