Malignant phyllodes tumor of the left atrium

Metastatic tumors to the heart usually involve right sided chambers. We report a rare case of malignant phyllodes tumor of breast with metastatic involvement of left atrium occurring through direct invasion from mediastinal micro-metastasis and presenting as a left atrial mass causing arrhythmia.     

KIF1A‐related disorders in children: A wide spectrum of central and peripheral nervous system involvement

KIF1A‐related disorders (KRD) were first described in 2011 and the phenotypic spectrum has subsequently expanded to encompass a range of central and peripheral nervous system involvement. Here we present a case series demonstrating the range of clinical, neurophysiological, and radiological features which may occur in childhood‐onset KRD. We report on all the children and young people seen at a single large tertiary centre. Data were collected through a retrospective case‐notes review. Twelve individuals from 10 families were identified. Eight different mutations were present, including four novel mutations. Two patients displayed a very severe phenotype including congenital contractures, severe spasticity and/or dystonia, dysautonomia, severe sensorimotor polyneuropathy and optic atrophy, significant white matter changes on brain MRI, respiratory insufficiency, and complete lack of neurodevelopmental progress. The remaining 10 patients represented a spectrum of severity with common features including a movement disorder with spasticity and/or dystonia, subtle features of dysautonomia, sensory axonal neuropathy, varying degrees of optic atrophy and of learning and/or behavioural difficulties, and subtle or absent—but sometimes progressive—changes in white matter on MRI. Epilepsy was common among the more severely affected children. This case series demonstrates that KRD comprise a range of neurological disorders, with both the milder and the more severe forms combining central and peripheral (including autonomic) nervous system deficits.     

Celiac axis compression by median arcuate ligament on computed tomography among asymptomatic persons

Background/Aim  

Compression of celiac artery by median arcuate ligament (MAL) may cause abdominal symptoms. This study looked at the prevalence of this finding in asymptomatic persons.     

Ascaris lumbricoides in the lacrimal passage

Ascariasis is caused by the roundworm, Ascaris lumbricoides. We report an additional case of live Ascaris lumbricoides removed from the lacrimal puncta of a 10-year-old boy.     

Kangaroo-related motor vehicle collisions

BACKGROUND: Motor vehicle collisions that are caused by large animals affect motorists in most parts of the world and tend to be increasing in incidence. Although traffic accidents involving kangaroos are common in Australia, we are not aware of any series that reported human injuries caused by such accidents. We aimed to study the mechanism, type, and outcome of these injuries. METHODS: Forty-six patients (32 male and 14 female patients; median age, 31.5 years) who presented to Royal Perth Hospital and who had been involved in a motor vehicle collision that was related to kangaroos between July 1994 and June 2000 were studied. RESULTS: The patients had a median Injury Severity Score of 9 (range, 1-41); 67.4% were car collisions and 32.6% were motorbike collisions, 41.3% had direct collision with a kangaroo, 34.8% hit a secondary object, and 32.6% rolled over. Most of these injuries affected the head and face (54.3%), upper extremities (57.4%), and lower extremities (40.4%). Only four had intracranial injuries (8.7%). Ninety percent of these collisions occurred at night, 74% in the countryside and 85% on highways or streets. The incidence was reduced during winter. Only one patient in this series died (2.2%). CONCLUSION: Most kangaroo-related motor vehicle collisions occurred at night, in the countryside, and on highways when the driver tried to avoid a kangaroo. Although injuries resulting from these collisions are relatively mild, increased awareness of their presence and ways to reduce them have to be promoted.     

Bilateral hydroureter and hydronephrosis causing renal failure due to a procidentia uteri: a case report

We report a case of complete uterine prolapse that resulted in bilateral hydroureter, hydronephrosis, and renal dysfunction. The nonoperative reduction of the prolapse with a vaginal pessary reversed the obstructive uropathy and ameliorated renal function. The lower urinary tract should be imaged in patients with complete uterine prolapse. If present, obstructive uropathy should be relieved by the reduction of the prolapse before irreversible renal damage occurs.