全文获取类型
收费全文 | 263篇 |
免费 | 24篇 |
专业分类
儿科学 | 23篇 |
妇产科学 | 4篇 |
基础医学 | 47篇 |
口腔科学 | 2篇 |
临床医学 | 15篇 |
内科学 | 56篇 |
皮肤病学 | 2篇 |
神经病学 | 4篇 |
特种医学 | 18篇 |
外科学 | 36篇 |
综合类 | 5篇 |
预防医学 | 11篇 |
眼科学 | 2篇 |
药学 | 51篇 |
中国医学 | 1篇 |
肿瘤学 | 10篇 |
出版年
2021年 | 5篇 |
2018年 | 5篇 |
2017年 | 2篇 |
2016年 | 5篇 |
2015年 | 5篇 |
2014年 | 2篇 |
2013年 | 8篇 |
2012年 | 3篇 |
2011年 | 7篇 |
2010年 | 7篇 |
2009年 | 6篇 |
2008年 | 5篇 |
2007年 | 8篇 |
2006年 | 12篇 |
2005年 | 9篇 |
2003年 | 4篇 |
2002年 | 3篇 |
2001年 | 5篇 |
2000年 | 4篇 |
1999年 | 3篇 |
1998年 | 7篇 |
1997年 | 10篇 |
1996年 | 9篇 |
1995年 | 2篇 |
1993年 | 4篇 |
1992年 | 3篇 |
1991年 | 8篇 |
1990年 | 7篇 |
1989年 | 11篇 |
1988年 | 11篇 |
1987年 | 4篇 |
1986年 | 7篇 |
1985年 | 7篇 |
1984年 | 6篇 |
1983年 | 6篇 |
1982年 | 4篇 |
1981年 | 7篇 |
1980年 | 8篇 |
1979年 | 7篇 |
1978年 | 7篇 |
1977年 | 3篇 |
1976年 | 4篇 |
1975年 | 4篇 |
1974年 | 7篇 |
1973年 | 2篇 |
1971年 | 3篇 |
1970年 | 4篇 |
1968年 | 3篇 |
1966年 | 3篇 |
1934年 | 3篇 |
排序方式: 共有287条查询结果,搜索用时 0 毫秒
101.
A. Mahmood N. Agarwal S. Sanyal D. Subrahmanyam 《Basic & clinical pharmacology & toxicology》1978,43(2):99-102
Abstract A considerable increase occurs in D-glucose uptake and brush border sucrase and lactase activities in the intestine of monkeys treated with a single oral dose of DDT. Brush border alkaline phosphatase activity remains unaffected in the pesticide treated animals. In vitro addition of DDT has no effect on the sugar absorption and disaccharidase activities. 相似文献
102.
103.
104.
105.
A single oral dose of 1,1,1-trichloro-2,2-bis-(p-chlorophenyl)ethane (DDT) (600 body weight) was given to rats and the levels of various lipids in adipose tissue, liver and plasma were studied. No alteration was observed in the levels of various lipid classes in these tissues except for a decrease in the phospholipid and triglyceride fractions of liver. Lipoprotein lipase activity of post-heparin plasma (protamine-sensitive and -resistant) was significantly decreased, whereas in liver and adipose tissue, the activity of this enzyme remained unchanged. 相似文献
106.
107.
108.
The binding of 10 different lectins to the surface of microfilariae of Wuchereria bancrofti has been investigated. Wheat germ agglutinin (WGA) and Helix pomatia lectin (HPA) bound specifically to the sheathed microfilariae indicating the presence of N-acetyl-D-glucosamine and N-acetyl-D-galactosamine respectively on the surface. Exsheathed microfilariae did not react with any of the lectins. Treatment of sheathed microfilariae with proteases resulted in increased binding of WGA and HPA. Such treated microfilariae showed a weak binding of Concanavalin A (Con A), and lectins of lentil (LCH) and of Limulus polyphemus (LPA). Sheathed microfilariae incubated with sera of people living in endemic zones of filariasis but with no apparent evidence of infection (endemic normals), or with sera of chronic elephantiasis patients, or with their respective gamma globulin fractions, bound Con A and LCH. These lectins bound weakly to exsheathed microfilariae under the same conditions. Binding was due to the mannose components of the specific immunoglobulins of the sera which coated the microfilariae. However, microfilariae when incubated with sera or their globulin fractions from non-endemic normals (NEN), or from microfilarial carriers, did not bind Con A and LCH, suggesting that specific immunoglobulins were neither present in NEN sera nor in significant amounts in sera of microfilarial carriers. 相似文献
109.
R Chandrashekar U R Rao P B Parab D Subrahmanyam 《The Southeast Asian journal of tropical medicine and public health》1985,16(1):15-21
Sheathed and exsheathed microfilariae of Brugia malayi are killed by normal rat cells in the presence of immune serum in vitro. Immune serum heated at 56 degrees C for 1 hour lost this activity which was largely restored by the addition of fresh normal rat serum. EDTA but not EGTA abolished this activity indicating the operation of complement by alternate pathway. Fresh normal rat serum alone promoted cellular adherence without exerting cytotoxicity to the microfilariae. The activity in the immune serum could be removed with Staphylococcus aureus cells containing Protein A or anti-IgG antiserum. The activity could also be absorbed to and eluted from Protein A--sepharose CL-4B suggesting the involvement of IgG. Neutrophils and macrophages participate in the antibody dependent cell-mediated cytotoxicity phenomenon. Eosinophils while adhering to the microfilariae exert cytotoxicity only to the exsheathed parasites. 相似文献
110.