全文获取类型
收费全文 | 36107篇 |
免费 | 1945篇 |
国内免费 | 110篇 |
专业分类
耳鼻咽喉 | 439篇 |
儿科学 | 2141篇 |
妇产科学 | 707篇 |
基础医学 | 4602篇 |
口腔科学 | 819篇 |
临床医学 | 2533篇 |
内科学 | 7343篇 |
皮肤病学 | 849篇 |
神经病学 | 1899篇 |
特种医学 | 861篇 |
外科学 | 4970篇 |
综合类 | 1347篇 |
一般理论 | 15篇 |
预防医学 | 2111篇 |
眼科学 | 1542篇 |
药学 | 3502篇 |
中国医学 | 274篇 |
肿瘤学 | 2208篇 |
出版年
2023年 | 236篇 |
2022年 | 669篇 |
2021年 | 1156篇 |
2020年 | 636篇 |
2019年 | 856篇 |
2018年 | 1051篇 |
2017年 | 724篇 |
2016年 | 957篇 |
2015年 | 991篇 |
2014年 | 1353篇 |
2013年 | 1754篇 |
2012年 | 2409篇 |
2011年 | 2431篇 |
2010年 | 1383篇 |
2009年 | 1241篇 |
2008年 | 1775篇 |
2007年 | 1742篇 |
2006年 | 1761篇 |
2005年 | 1385篇 |
2004年 | 1386篇 |
2003年 | 1178篇 |
2002年 | 1005篇 |
2001年 | 824篇 |
2000年 | 867篇 |
1999年 | 732篇 |
1998年 | 326篇 |
1997年 | 236篇 |
1996年 | 236篇 |
1995年 | 228篇 |
1994年 | 181篇 |
1993年 | 158篇 |
1992年 | 500篇 |
1991年 | 404篇 |
1990年 | 432篇 |
1989年 | 401篇 |
1988年 | 363篇 |
1987年 | 362篇 |
1986年 | 354篇 |
1985年 | 342篇 |
1984年 | 270篇 |
1983年 | 222篇 |
1982年 | 145篇 |
1979年 | 231篇 |
1978年 | 151篇 |
1977年 | 182篇 |
1975年 | 173篇 |
1974年 | 182篇 |
1973年 | 182篇 |
1972年 | 173篇 |
1971年 | 161篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
81.
82.
Lileswar Kaman Byju Kundel Saroj Kant Sinha Rajinder Singh 《Indian journal of gastroenterology》2003,22(2):65-66
Ephiphrenic esophageal diverticulum is rare and usually is a pulsion-type pseudodiverticulum that occurs in association with motility disorders of the esophagus. We report a 35-year-old man with tubercular lymphadenitis causing true traction type of epiphrenic diverticulum. Esophageal diverticulectomy and esophagomyotomy was done; he is doing well on antitubercular drugs. 相似文献
83.
Calciphylaxis – a topical overview 总被引:3,自引:0,他引:3
G Arseculeratne† AT Evans‡ SM Morley† 《Journal of the European Academy of Dermatology and Venereology》2006,20(5):493-502
'Calciphylaxis', a calcification syndrome associated with ischaemic cutaneous necrosis, is acquired naturally in humans in disease states. It is a life and limb-threatening complication, usually observed in patients with renal disease and secondary hyperparathyroidism, but known to occur in the absence of renal or parathyroid disease. The reported mortality rate, which ranges from 60-80%, relates to wound infection, sepsis and organ failure. It is a small-vessel vasculopathy, which is estimated to occur in about 4% of haemodialysis patients. Clinically, violaceous, reticulate areas of cutaneous necrosis and eschar may be evident, particularly in the extremities. In addition to the clinical picture, a raised calcium phosphorous product, an elevated parathyroid hormone level, radiographic evidence of vessel and soft-tissue calcification and the finding of mural calcification affecting small arteries and arterioles on histopathology help to confirm the diagnosis of this entity which generally has a poor prognosis. A high index of suspicion and an active multidisciplinary management approach, with rigorous attention to wound care and prevention of sepsis, are vital in the management of these patients. In this overview, we discuss the pathophysiology, clinical features and associations, risk factors, diagnosis and management issues relating to calciphylaxis. 相似文献
84.
85.
86.
G R Verma Lileshwar Kaman Gurpreet Singh Rajinder Singh Arunanshu Behera Shashank Mohan Bose 《Indian journal of gastroenterology》2006,25(1):16-19
AIM: Retrospective analysis of experience with management of external duodenal fistula (EDF) without using total parenteral nutrition (TPN). METHOD: Medical records of 31 patients with EDF following closure of duodenal ulcer perforation, treated over a 7-year period (1994-2001), were studied. Twenty-one patients (68%) had evidence of sepsis at presentation or during the course of treatment. None could afford TPN for optimum time. All patients received hospital-based enteral nutrition through nasojejunal tube, besides supportive medical treatment and/or surgery. Peritonitis or failure to insert nasojejunal tube for enteric alimentation led to early surgery. RESULTS: Two patients died of septicemia and multi-organ failure within 48 hours of admission. Fourteen patients (48.3%) initially received conservative treatment (Group I); six of them later required surgery. Fifteen patients (51.7%) underwent early surgery due to peritonitis (n=9) or failure to establish enteral feeding (n=6) (Group II); wound infection, intra-abdominal abscess and septicemia were more common in these patients than those in Group I. Survival rate was higher in Group I than in Group II (86% versus 40%; p< 0.05). Septicemia and gastrectomy were the independent factors associated with high mortality. CONCLUSIONS: EDF can be satisfactorily managed without TPN. Successful placement of enteral feeding line, supportive treatment and delayed surgery can achieve survival in 85% of patients. Minimum intervention is recommended when early surgery is performed in peritonitis or to establish enteral feeding line. 相似文献
87.
U N Verma R R Singh R Misra S Naik S S Agarwal 《Annals of the rheumatic diseases》1992,51(10):1159-1161
The case is described of a patient with scleromyxoedema with features typical of systemic sclerosis. The features were so characteristic that the disease was misdiagnosed as systemic sclerosis. A brief review of the association of the two diseases is given. 相似文献
88.
Four week swim exercise schedule (45 min day-1, 6 days each week) in rats led to a significant adaptive change in functional responsiveness of dopamine receptors (auto-receptors) in the nigrostriatal and mesolimbic system that was evident from the modification of behavioural responses elicited by a low dose of apomorphine, a direct acting dopamine receptor agonist. Thus, a remarkable increase in yawning response, development of full blown stereotypy, as well as profound attenuation of locomotory and hypothermic response was observed in exercise-trained rats as compared with the non-exercise group (control), following intraperitoneal administration of 0.3 mg kg-1 of apomorphine. 相似文献
89.
Two cases of acute polymyosotis associated with W. bancrofti , presented with generalised painful swelling and weakness of the muscles. These patients had elevated muscle enzymes, a myopathic EMG pattern, inflammatory myopathy on biopsy and W. bancrofti in the peripheral blood smear. The clinical, improvement of the disorder and total clearance of microfilariae was obtained with the combination therapy of steroid and diethyl-carbamazine in comparison with steroid alone. 相似文献
90.
We investigated the effects of hypercalcemia on pancreatic duct permeability and pancreatitis in cats. Acute hypercalcemia was maintained by an infusion of calcium gluconate; controls received saline solution. Chronic hypercalcemia was maintained by diet and by vitamin D and dihydrotachysterol injections. Portal venous blood was analyzed for large dextran molecules that had been perfused through the pancreatic duct. In a separate group of hypercalcemic animals, we perfused the duct with activated pancreatic enzymes to induce acute pancreatitis. After 24 hours of hypercalcemia, dextrans were detected in the portal venous blood of 6 of 11 hypercalcemic and none of the 6 control animals (p less than 0.05). After 12 hours of hypercalcemia, dextrans were detected in all 7 hypercalcemic and 1 of 7 control animals (p less than 0.001). The degree of pancreatic inflammation was greater in the 12-hour animals than in the controls (p less than 0.001). After 14 days of hypercalcemia, however, there were no differences in dextran permeability or pancreatitis in experimental or control animals. Our results indicate that acute hypercalcemia increases the permeability of the pancreatic duct to molecules the size of pancreatic enzymes. This could be important in the pathogenesis of acute pancreatitis associated with hypercalcemic states. 相似文献