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81.
82.
万艾可治疗ED时对BPH引起LUTS改善的研究 总被引:6,自引:3,他引:3
目的 :探索、研究万艾可在治疗阴茎勃起功能障碍 (ED)时对由良性前列腺增生 (BPH)引起的下尿路症状(LUTS)的影响。 方法 :32例ED同时伴有BPH的研究对象 ,采用IIEF 5问卷表和IPSS评分表 ,在服用万艾可前和服药后 6个月分别各填写一次 ,应用单因素方差分析对所得到的前后评分进行统计学分析。结果 :在服药前32例ED中 ,轻、中、重分别为 14、13、5例 ,BPH中轻、中、重分别为 3、15、14例 ;服药后IIEF 5评分平均上升4 2 .36 % ,IPSS评分平均下降 2 0 .14 % ,两者在统计学上都有显著性差异 ,P <0 .0 1。 结论 :在治疗中老年性ED合并BPH中 ,应用万艾可既能治疗ED ,取得完美的性生活 ,又能达到改善由BPH引起的LUTS。万艾可是一治疗ED有效的药物 ,但对于前列腺基质平滑肌亦有辅助性松弛作用 ,因此也有助于BPH时LUTS的缓解。 相似文献
83.
J. Francisco Salomão Sérgio Cavalheiro Hamilton Matushita René D. Leibinger Antonio R. Bellas Elide Vanazzi Luiz A. M. de Souza Andréa G. Nardi 《Child's nervous system》2006,22(3):234-242
Background Cystic dysraphic lesions of the cervical and upper thoracic region are rare and only a few series have been published about the topic. These malformations can be divided into categories that include both myelocystoceles and the so-called cervical meningoceles or myelomeningoceles.Methods A retrospective study of 18 patients was conducted.Results In 17 patients a squamous or a cicatricial epithelium of variable thickness covered the dome of the lesions, while the base was covered with full-thickness skin. In one case the skin was entirely normal. Four patients displayed associated CNS malformations and three more had systemic congenital anomalies. All patients underwent surgical exploration and the length of time between birth and surgery ranged from 6 h to 9 months. The most frequent surgical finding, seen in 14 patients, was a stalk connecting the dorsal surface of the spinal cord to the cyst. In three patients the findings were consistent with myelocystocele. Only in one case was a true meningocele found. Hydrocephalus and Chiari II malformation were not as consistently associated as in myelomeningoceles. Neurological signs and symptoms were not so marked as in myelomeningoceles and were found in the follow-up of four patients. In two of them there was a non-progressive deficit, probably expressing an imperceptible involvement of the nervous system in the first year of life. The histopathological findings were of three types: neuroglial stalks, fibrovascular stalks and myelocystoceles.Conclusions Cystic dysraphisms of the cervical and upper thoracic region differ clinically and structurally from meningomyelocele and have a more favorable outcome. We believe that these malformations have not been properly labeled and propose a classification based on the structures found inside the cyst. 相似文献
84.
目的:脉压(PP)升高一贯用来预测有心血管疾病危险患者和轻度慢性心衰(CH F)患者的心血管疾病发生率和死亡率增高。相反,PP降低与急性失代偿性心衰患者死亡率升高相关。然而,尚不清楚PP对于晚期CH F患者的预测价值。方法和结果:采用Cox比例风险回归分析研究了1901例N YH A III或IV级CH F患者(平均年龄65岁,平均射血分数26%)的资料,经校正其他危险因素后,分析PP对死亡率的影响。检测了1个亚组患者的利钠肽水平。多元Cox回归分析表明,PP降低与死亡率增高相关(每增加10m m H g的H R为0.91,95%CI0.93~0.99),这一相关性独立于平均… 相似文献
85.
对30例稳定性心衰患者进行放射性核素心室造影和时相分析,确定基线时和最大耐受剂量卡维地洛治疗6个月后左心室和心室间的收缩同步性。与正常人群相比,心衰患者具有明显的心室不同步。基线时具有最显著不同步的患者中第50位百分位数表明,接受卡维地洛治疗后心室同步性得到显著改善,这与舒张末期左心室容量降低呈正相关。卡维地洛对慢性心衰患者心室内和心室间同步性的影响@Castro P. F.$Dr. Faculty of Medicine, P. Catholic University of Chile, University of Chile, Santiago, Chile
@Mc-Nab P.
@Quintana J. C.
@王… 相似文献
86.
Haiwei Wu Binhui Ren Jiaquan Zhu Guohua Dong Biao Xu Changtian Wang Xiaogang Zheng Hua Jing 《European journal of cardio-thoracic surgery》2006,29(6):902-907
Objective: Based on the findings that erythropoietin (EPO) has been proved to be a multiple functional cytokine to attenuate ischemia–reperfusion (I/R) injury in various organs such as brain, heart, and kidney in animals, this experiment was designed to evaluate the effect of pretreatment with recombined human erythropoietin (rhEPO) on I/R-induced lung injury. Methods: Left lungs of rats underwent 90 min of ischemia and then were reperfused for up to 2 h. Animals were randomly divided into three experimental groups as sham group, I/R group, and rhEPO + I/R group (a single dose of rhEPO was injected intraperitoneally 3000 U/kg 24 h prior to operation). Lung injury was evaluated according to semi-quantitive analysis of microscopic changes, tissue polymorphonuclear neutrophils (PMNs) accumulation (myeloperoxidase (MPO) activity), and pulmonary microvascular permeability (Evan's blue dying method). Peripheral arterial and venous blood samples were obtained for blood–gas analysis after 5 min occlusion of right lung hilus at the end of reperfusion. The serum concentration of tumor necrosis factor (TNF)- was also measured by the method of enzyme-linked immunosorbent assay. Results: Histological injury scoring revealed significantly lessened lung alveolus edema and neutrophils infiltration in the rhEPO pretreated group compared with I/R group (p < 0.05). The rhEPO pretreated animals exhibited markedly decreased lung microvascular permeability (p < 0.05) and myeloperoxidase activity (p < 0.05). Blood–gas analysis demonstrated that the pretreated animals had significantly ameliorated pulmonary oxygenation function (p < 0.05). The serum concentration of tumor necrosis factor- in rhEPO pretreated group was markedly decreased compared with that of I/R group (p < 0.05). Conclusions: Pretreatment with rhEPO appears to attenuate I/R-induced lung injury. This function is partly related with the capacity that rhEPO inhibits the accumulation of polymorphonuclear neutrophils in lung tissue and decreases the systematic expression of tumor necrosis factor-. 相似文献
87.
国产氟康唑对小鼠隐球菌病的疗效 总被引:1,自引:1,他引:0
以5×103cfu/鼠的新型隐球菌给小鼠脑室感染(ic)1h后,分别口服氟康唑(Flu)5和10mg/(kg·d)或酮康唑(Ket)50和100mg/(kg·d),bid×9d。对ic小鼠连续观察40天的存活率和平均存活时间,Ful分别为50%~70%和8~15天,Ket是30%~40%和5~9天。由小鼠侧尾静脉注射106cfu/鼠新型隐球菌3天后产生的全身感染,分别给小鼠口服Flu2.5~10mg/(kg·d)或Ket25~100mg/(kg·d),bid×9d。感染24、28和32天的PD50Flu是2.7、3.5和6.7mg/kg,Ket为28.4、70.4和83mg/kg;Flu和Ket的平均存活时间分别是23~34天和20~31天。在上述两种实验模型中分离脑和肺做细菌培养,Flu均与对照和50mg/(kg·d)的Ket比较,对ic10天及静脉注射感染13天的小鼠,口服5和10mg/(kg·d)或2.5~10mg/(kg·d)Flu均显著抑制新型隐球菌生长。 相似文献
88.
本文就益肾通淋汤对尿结石病人尿中的草酸钙结晶的影响进行了随机对照观察。结果:实验组尿中出现草酸钙结晶、大晶体、结晶聚体的例数比对照组少(P<0.01)。提示益肾通淋汤有抑制尿石病人尿中草酸钙结晶的析出、增大和聚集的作用,以及可能有预防尿结石的形成和复发的作用。 相似文献
89.
90.
脂肪栓塞综合征:附19例报告 总被引:2,自引:0,他引:2
脂肪栓塞综合征是创伤或骨折的严重并发症,死亡率高,通过对19例临床观察分析及复习文献,提出对本征诊断有重要意义的4项标准:(1)“暴风雪”样肺片;(2)皮肤或粘膜有出血点;(3)低氧血症;(4)血小板减少,并认为应用高压氧治疗本征是一种有效的方法。 相似文献