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Renate Gänszle 《Zeitschrift für Psychodrama und Soziometrie》2010,9(1):63-74
Lovers are changing their roles when they are expecting a child. This paper deals about how their roles will modify during this process. On the basis of three examples it will be presented what kind of change and conflicts are expected and how psycho-dramatic methods can help. This practice supports parents on the way through pregnancy to define a place for the expected child in their love relationship. 相似文献
104.
Sebastian Müller Ingo Marenholz Young-Ae Lee Claudia Sengler Simona Eva Zitnik Rupino W. Griffioen Paolo Meglio Ulrich Wahn Renate Nickel 《Pediatric allergy and immunology》2009,20(4):358-361
Many candidate gene studies for atopic dermatitis (AD) and associated phenotypes have been conducted so far, but replication of significant results has been a major problem. Two loss of function polymorphisms FLG R501X- and 2282del4, in the Filaggrin ( FLG ) gene encoding for an epidermal barrier protein were recently identified. They were reported to be predisposing factors for AD and concomitant asthma. Several groups confirmed the initial results in independent populations. The aim of this study is to further investigate the importance of these FLG variants in the development of AD and subsequent asthma symptoms in pre-school children, we investigated children and parents of the Early Treatment of the Atopic Child (ETAC)-trial. We genotyped 496 children and 488 parents of the ETAC population for the two FLG variants, evaluating an association by family based analysis (transmission disequilibrium test). We found a highly significant association of the FLG null variants R501X- and 2282del4 with AD (combined genotype p < 0.0001) and asthma (combined genotype p < 0.0001). The replication and its statistical significance underlines the importance of the FLG polymorphisms and the importance of the skin barrier function in the development of AD and subsequent asthma. 相似文献
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Christian Geretsegger Waltraud Bitterlich Renate Stelzig Christoph Stuppaeck Brigitta Bondy Wolfgang Aichhorn 《European neuropsychopharmacology》2008,18(2):141-146
Pindolol, a 5-HT1A autoreceptor antagonist, given in combination with selective serotonin reuptake inhibitors (SSRIs), may enhance and/or accelerate the therapeutic efficacy of SSRIs. Fifty patients, meeting ICD-10 criteria for major depressive disorder or bipolar depression, were enrolled in our randomized, placebo-controlled, double-blind trial. One group received paroxetine plus pindolol (2.5 mg t.i.d.), and the other group received paroxetine plus placebo. The proportion of patients with sustained response (>or=50% reduction of baseline HAM-D 17 score maintained until the endpoint; p=0.252) and the proportion of patients with remission (HAM-D 17 相似文献
107.
Michael Stierer Harald Rosen Renate Weber Hanns Hanak Leo Auerbach Jürgen Spona Heinz Tüchler 《Breast cancer research and treatment》1995,36(1):11-21
Summary The immunohistochemnichally determined receptor status, as well as first-generation risk factors (tumor size, lymph node status, histologic grading including subfactors, tumor histology, and biochemically determined receptor status) were prospectively analyzed in 288 cases of primary breast cancer for their impact on recurrence-free survival (RFS) and overall survival (OS) after a median observation period of 41 months.Immunohistochemically (ER-ICA) and biochemically determined estrogen receptors (ER-DCC), as well as tumor size, lymph node status, histologic grading, mitotic rate, and nuclear polymorphism, were of prognostic value for recurrence-free survival and/or overall survival.In multivariate analysis, lymph node status, tumor size, and mitotic rate proved to be independent prognosticators; ER-ICA showed significance in the univariate analysis which dropped, however, when multivariate analysis was applied.The prognostic power of histologic grading in our series seemed to depend mainly on the subfactors which relate to nuclear features. 相似文献
108.
Impaired hemorheology in patients with postmastectomy lymphedema 总被引:2,自引:0,他引:2
Manuela P. Djavanmard Ilse Michl M. Korpan Barbara Fazeny Alexandra C. Budinsky Elmar Wiesinger Georg Weinländer Michael Binder Margot Püspök Christoph C. Zielinski Veronika Fialka Renate Koppensteiner Christine Marosi 《Breast cancer research and treatment》1996,38(3):283-288
Lymphedema of the arm is one of the most disabling and serious complications of breast cancer. Apart from tumor infiltration or fibrosis of lymphatic pathways, little is known about factors favoring the development of lymphedema. In the present study, we investigated the impact of rheologic parameters, e.g. red cell aggregation (EA) and plasma viscosity (PV), and of capillary morphology and capillary flow in patients with breast cancer with (n = 18) and without (n = 18) lymphedema. Patients with lymphedema showed a significant increase of red cell aggregation (p < 0.001) that indicates a systemic component of lymphedema and might offer a possibility of prevention and therapy of this condition. A hitherto unclassified protein factor favoring red cell aggregation and lymphedema might be postulated. 相似文献
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Congenital and acquired nystagmus, particularly pendular and jerk nystagmus, see-saw nystagmus and spasmus nutans, may be the presenting sign of a suprasellar mass lesion.(1) The large variety of different suprasellar mass lesions requiring quite different therapeutic measures necessitates exact histological diagnosis for optimal therapeutic strategy planning.(2) Stereotactic tumor biopsy has become a well-established diagnostic approach, combining minimal surgical trauma with a high degree of diagnostic safety. Particularly in the two most frequent suprasellar mass lesions - craniopharyngiomas and pilocytic astrocytomas - accurately planned stereotactic drainage of tumor cysts combined with radiotherapy and/or stereotactic radiosurgery allows successful decompression and tumor control as well as maximum preservation of visual and endocrinological functions when compared with conventional surgical procedures.(2-11) 相似文献