广泛软组织机械性损伤所致多脏器功能障碍综合征的实验研究

目的 研究广泛软组织机械性损伤所致多脏器功能和形态学改变。方法 健康纯种新西兰大白兔25只，随机分成实验组（17只）和对照组（8只）。对实验组动物进行全身大量失血再灌注复合双后肢肌肉丰富部位挤压伤，造成广泛软组织机械性损伤，分别于放血前、减压后24、48、72h采取动物血检测尿素氮、肌酐、谷丙转氨酶；死后或72h活杀后取心、肺、肝、肾、脑及受压后腿肌组织，备行光镜和透射电镜观察，肾组织行肌红蛋白免疫组化染色观察。对照组无上述致伤过程，与实验组对应时刻取血测定上述生化指标，72h提取组织行光、电镜观察。结果 伤后实验动物上述功能指标有显著性改变，形态学有明显改变。结论 广泛软组织机械性损伤可导致多脏器功能障碍综合征的发生，肾组织肌红蛋白免疫组化染色和其他受损器官的组织学雯化为实践中此类损伤引起死亡的定性提供了法医病理学的诊断依据。     

Experimental research on the relationship between fit accuracy and fracture resistance of zirconia abutments

Objectives

The purpose of the study was to investigate the correlation between fit accuracy and fracture resistance of zirconia abutments, as well as its feasibility for clinical applications.

Methods

Twenty self-made zirconia abutments were tested with 30 Osstem GSII implants. First, 10 Osstem GSII implants were cut into two parts along the long axis and assembled with the zirconia abutments. The microgaps between the implants and the zirconia abutments were measured under a scanning electron microscope. Second, the zirconia abutments were assembled with 20 un-cut implants and photographed before and after being fixed with a central screw of 30-N cm torque. The dental films were measured by Digora for Windows 2.6 software. Then the fracture resistance of zirconia abutments was measured using the universal testing machine at 90°. All results were analyzed using SPSS13.0 software.

Results

The average internal-hexagon microgaps between the implants and zirconia abutments were 19.38 ± 1.34 μm. The average Morse taper microgap in the implant–abutment interface was 17.55 ± 1.68 μm. The dental film showed that the Morse taper gap in the implant–abutment interface disappeared after being fixed with a central screw of 30-N cm torque, and the average moving distance of the zirconia abutments to the implants was 0.19 ± 0.02 mm. The average fracture resistance of zirconia abutments was 282.93 ± 17.28 N. The internal-hexagon microgap between the implants and zirconia abutments was negatively related to the fracture resistance of the abutments (r₁ = −0.97, p < 0.01). The Morse taper microgap in the implant–abutment interface was negatively related to the fracture resistance of the abutments (r₂ = −0.84, p < 0.01).

Conclusions

The microgap between implant and abutment was negatively related to the fracture resistance of the abutment, while the internal-hexagon microgap has better correlation than the Morse taper microgap. The closure of microgap is helpful to improve the fracture resistance of zirconia abutments. The fracture resistance of zirconia abutments can satisfy the clinical application.     

Oral health behaviors and metabolic syndrome: the 2008–2010 Korean National Health and Nutrition Examination Survey

Objectives

This study examined whether oral health behaviors are associated with metabolic syndrome (MetS) in Korean adults involved in the 2008–2010 Korea National Health and Nutrition Examination Survey (KNHANES).

Materials and methods

A total of 18,742 subjects (8,034 men and 10,708 women) were included. MetS was defined according to the criteria of the American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement for Asians. Oral health behavior was assessed using a questionnaire included in the KNHANES.

Results

Subjects with MetS brushed their teeth less frequently and used fewer secondary oral products than subjects without MetS (p?<?0.01). As frequency of toothbrushing and number of secondary oral products increased, body mass index, waist circumference, diastolic blood pressure, fasting plasma glucose, triglyceride, and white blood cell count decreased, but high-density lipoprotein–cholesterol increased (all p for trend <0.01). In the multivariable logistic regression models, as frequency of toothbrushing increased, the odds ratios (ORs) for MetS, abdominal obesity, and hyperglycemia are more than one after adjusting for age, gender, education, income, alcohol and tobacco use, physical activity, and the components of MetS. The ORs for MetS, abdominal obesity, and high blood pressure were more than one in subjects who do not use dental floss after adjusting for all covariates.

Conclusion

MetS is associated with infrequent daily toothbrushing and disuse of dental floss in South Korean.

Clinical relevance

Dentists may recommend evaluation for MetS in the patients with infrequent daily toothbrushing and disuse of dental floss.