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Sulfonic ester is a chemical structure common to many organic molecules, including biologically active compounds. Herein, a visible-light-induced synthetic method to prepare aryl sulfonic ester from arylazo sulfones was developed. In the present study, a one-pot reaction was carried out using arylazo sulfones, DABSO (DABCO·(SO2)2), and alcohols in the presence of CuI as a coupling catalyst and HCl as an additive to yield sulfonic esters via multicomponent reaction. This synthetic method afforded a wide range of sulfonic esters with high yields under mild conditions.Facile and efficient one-pot synthesis of sulfonic esters has been achieved via visible-light-induced multicomponent reaction of arylazo sulfones, and alcohols in the presence of DABSO, CuI, and HCI. 相似文献
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Lam Thi Kieu Giang Karolina Trejgis ukasz Marciniak Agnieszka Opaliska Iwona E. Koltsov Witold ojkowski 《RSC advances》2022,12(23):14644
Correction for ‘Synthesis and characterizations of YZ-BDC:Eu3+,Tb3+ nanothermometers for luminescence-based temperature sensing’ by Lam Thi Kieu Giang et al., RSC Adv., 2022, 12, 13065–13073, https://doi.org/10.1039/D2RA01759H.The authors regret the omission of a funding acknowledgement in the original article. This acknowledgement is given below.Karolina Trejgis is supported by the Foundation for Polish Science (FNP).The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers. 相似文献
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Anh-Hoa Nguyen Pham Kim-Oanh Bui Thi Mai-Huong Nguyen Thi Diem-Ngoc Ngo Nakayuki Naritaka Hiroshi Nittono Hisamitsu Hayashi Trang Thi Dao Kim-Huong Thi Nguyen Hoai-Nghia Nguyen Hoa Giang Hung-Sang Tang Tat-Thanh Nguyen Dinh-Kiet Truong Minh-Dien Tran 《Medicine》2022,101(25)
Rationale:Congenital bile acid synthesis defect (BASD) is a rare disease caused by mutations in the aldo-keto reductase 1D1 gene, which encodes the primary Δ4-3-oxosteroid 5β-reductase enzyme. Early disease diagnosis is critical for early treatment with bile acid replacement therapy, with an excellent chance for recovery. In contrast, protracted diagnosis and treatment may lead to poor outcomes, including decompensated hepatic cirrhosis, liver transplant, and even death.Patient concerns:Three clinical congenital bile acid synthesis defect cases in the Vietnamese population are herein reported. These pediatric patients presented with symptoms of prolonged postpartum jaundice and abnormal loose stool (mucus, lipids, and white). The clinical examinations showed hepatosplenomegaly. Urinalysis showed a very low fraction of primary bile acids and atypical 3-oxo-Δ4- bile acids in all three patients.Diagnoses:The patients were diagnosed with primary Δ4-3-oxosteroid 5β-reductase deficiency. Next-generation gene sequencing revealed two homozygous mutations in the aldo-keto reductase family 1 member D1 gene. The first is a documented variant, c.797G>A (p.Arg266Gln), and the second is a novel mutation at c.155T>C (p.Ile52Thr).Interventions:Immediately after diagnosis, patients were treated with oral chenodeoxycholate 5 mg/kg/d.Outcomes:The patients’ symptoms, signs, and primary bile acids levels improved significantly.Lessons:Clinicians should consider genetic disorders related to cholestasis for effective and life-saving treatment. A prompt genetic analysis by next-generation gene sequencing enables patients to access bile acid replacement therapy earlier, significantly improving short- and long-term outcomes. 相似文献
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Kieu Anh Thi Nguyen Thu Tuyet Nguyen Dong Vinh Nguyen Giang Chau Ngo Cam Nhat Nguyen Kentaro Yamada Kazuko Noguchi Kamruddin Ahmed Hanh Duc Hoang Akira Nishizono 《Tropical Medicine and Health》2015,43(2):111-116
Rapid and easy determination of protective neutralization antibody (NAb) against rabies in the field is very important for an early and effective response to rabies in both animal and human health sectors. The rapid neutralizing antibody detection test (RAPINA), first developed in 2009 and then improved in 2012, is a quick test allowing detection of 0.5 IU/ml antibodies in human and animal sera or plasma. This study aimed to assess the RAPINA test by comparison with rapid focus fluorescence inhibition test (RFFIT), using 214 sera of vaccinated and unvaccinated professional dog butchers, laboratory workers and rabies patients in Vietnam. The sensitivity, specificity, false negative rate, false positive rate and concordance of the RAPINA test as compared to RFFIT were 100%, 98.34%, 0%, 1.66% and 98.6%, respectively. The positive predictive value and negative predictive value were 91.7% and 100%, respectively when RAPINA test was used. With its remarkable sensitivity, specificity and easy implementation, RAPINA test can be used for rapid determination of NAb in the field. 相似文献
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Nguyen Truong Giang Le Tien Dung Nguyen Thanh Hien Truong Thanh Thiet Phan Sy Hiep Dinh Cong Pho Pham Ngoc Hung 《Annals of thoracic and cardiovascular surgery》2021,27(1):10
Objectives: To evaluate plombage surgery for hemoptysis control in pulmonary aspergilloma in high-risk patients.Methods: This study was carried out on 75 pulmonary aspergilloma patients presenting with hemoptysis that underwent a plombage surgery for approximately 7 years (November 2011–September 2018) at Pham Ngoc Thach Hospital. They revisited the hospital 6 months after plombage surgery and considered plombage removal. The group whose plombage was removed was compared with that whose plombage was retained 6 and 24 months after surgery.Results: Hemoptysis reduced significantly after surgery. Hemoptysis ceased in 91.67% of the patients and diminished in 8.33% of the patients 6 months after surgery. Similarly, hemoptysis ceased in 87.32% of the patients and diminished in 12.68% of the patients 24 months after surgery. Body mass index (BMI) index, Karnofsky score, and forced expiratory volume in one second (FEV1) increased. Plombage surgery was performed with operative time of 129.5 ± 36.6 min, blood loss during operation of 250.7 ± 163.1 mL, and the number of table tennis balls of 4.22 ± 2.02. No deaths related to plombage surgery were recorded. Plombage was removed in 29 cases because of patients’ requirements (89.8%), infection (6.8%), and pain (3.4%). There were no patient developing complications after the treatment and there were no statistically significant differences between the two groups.Conclusions: Plombage surgery is safe and effective for hemoptysis control in pulmonary aspergilloma. To minimize the risk of long-term complications, surgeons should remove the plombage 6 months after the initial operation. 相似文献
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Imogen Moran Danielle T. Avery Kathryn Payne Helen Lenthall E. Graham Davies Siobhan Burns Winnie Ip Matÿfffedas M. Oleastro Ismail Reisli Sukru Guner Sevgi Keles Luigi Notarangelo Elissa K. Deenick Christopher C. Goodnow David Zahra Robert Brink Melanie Wong Tri Giang Phan 《The Journal of allergy and clinical immunology》2019,143(6):2302-2305
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