全文获取类型
收费全文 | 1351939篇 |
免费 | 97530篇 |
国内免费 | 4234篇 |
专业分类
耳鼻咽喉 | 19887篇 |
儿科学 | 40350篇 |
妇产科学 | 38897篇 |
基础医学 | 189324篇 |
口腔科学 | 40012篇 |
临床医学 | 114787篇 |
内科学 | 265406篇 |
皮肤病学 | 30368篇 |
神经病学 | 107192篇 |
特种医学 | 54327篇 |
外国民族医学 | 446篇 |
外科学 | 210085篇 |
综合类 | 34097篇 |
现状与发展 | 6篇 |
一般理论 | 438篇 |
预防医学 | 93001篇 |
眼科学 | 31889篇 |
药学 | 101972篇 |
18篇 | |
中国医学 | 3925篇 |
肿瘤学 | 77276篇 |
出版年
2018年 | 12425篇 |
2016年 | 11153篇 |
2015年 | 12695篇 |
2014年 | 17689篇 |
2013年 | 26065篇 |
2012年 | 34314篇 |
2011年 | 36299篇 |
2010年 | 21558篇 |
2009年 | 20922篇 |
2008年 | 34558篇 |
2007年 | 37636篇 |
2006年 | 38165篇 |
2005年 | 36920篇 |
2004年 | 35689篇 |
2003年 | 34617篇 |
2002年 | 34071篇 |
2001年 | 64012篇 |
2000年 | 65751篇 |
1999年 | 55805篇 |
1998年 | 14973篇 |
1997年 | 13746篇 |
1996年 | 13201篇 |
1995年 | 12474篇 |
1994年 | 11632篇 |
1992年 | 42907篇 |
1991年 | 41422篇 |
1990年 | 40673篇 |
1989年 | 39653篇 |
1988年 | 37056篇 |
1987年 | 36487篇 |
1986年 | 34969篇 |
1985年 | 33150篇 |
1984年 | 24841篇 |
1983年 | 21070篇 |
1982年 | 12672篇 |
1981年 | 11583篇 |
1979年 | 23929篇 |
1978年 | 17073篇 |
1977年 | 14835篇 |
1976年 | 13388篇 |
1975年 | 15268篇 |
1974年 | 18082篇 |
1973年 | 17560篇 |
1972年 | 16811篇 |
1971年 | 15718篇 |
1970年 | 14915篇 |
1969年 | 14346篇 |
1968年 | 13460篇 |
1967年 | 12015篇 |
1966年 | 11258篇 |
排序方式: 共有10000条查询结果,搜索用时 203 毫秒
181.
182.
183.
184.
Jeroen M. van de Pol Jurjen G. Geljon Svetlana V. Belitser Geert W.J. Frederix Anke M. Hövels Marcel L. Bouvy 《Research in social & administrative pharmacy》2019,15(1):70-76
Introduction
The nature of community pharmacy is changing, shifting from the preparation and distribution of medicines to the provision of cognitive pharmaceutical services (CPS); however, often the provision of traditional services leaves little time for innovative services. This study investigated the time community pharmacists spend on the tasks and activities of daily practice and to what extent they are able to implement CPS-related services in daily practice.Methods
Self-reporting work sampling was used to register the activities of community pharmacists. A smartphone application, designed specifically for this purpose, alerted participants to register their current activity five times per working day for 6 weeks. Participants also completed an online survey about baseline characteristics.Results
Ninety-one Dutch community pharmacists provided work-sampling data (7848 registered activities). Overall, 51.5% of their time was spent on professional activities, 35.4% on semi-professional activities, and 13.1% on non-professional activities. The proportion of time devoted to CPS decreased during the workweek, whereas the time spent on traditional task increased.Discussion and conclusion
This study shows it is feasible to collect work-sampling data using smartphone technology. Community pharmacists spent almost half of their time on semi-professional and non-professional activities, activities that could be delegated to other staff members. In practice, the transition to CPS is hampered by competing traditional tasks, which prevents community pharmacists from profiling themselves as pharmaceutical experts in daily practice. 相似文献185.
186.
Background
Aromatic l-amino acid decarboxylase (AADC) deficiency (OMIM #608643) is a rare and severe disorder of biogenic amine synthesis caused by mutations in the DDC gene. The phenomenology of the movement disorder includes intermittent oculogyric crises and limb dystonia, generalized athetosis, and impaired voluntary movement.Objective
To identify clinical manifestations and DDC gene mutations in two Chinese mainland children who are siblings with AADC deficiency.Methods
We used targeted next-generation sequencing and quantitative polymerase chain reaction (qPCR) to reveal DDC mutations in these children.Results
Two DDC gene mutations were found: one missense mutation, c.1040G?>?A (p.Arg347Gln), is a reported mutation derived from the mother; the other mutation, a whole-exon 11 and 12 deletion, is a novel mutation derived from the father. The index patient and her brother both had poor sucking power and feeding difficulty at birth and episodes of oculogyric crises, truncal hypotonia, limb hypertonia, sleep disturbances, irritability, and motor delay. The siblings both died at 1?year and 10?months due to asphyxia and pneumonia during gaze and hypertonia episodes.Conclusion
This study identified a novel DDC gene deletion mutation in two siblings with AADC deficiency disease in the Chinese mainland population. 相似文献188.
Marie Warrer Petersen Tine Sylvest Meyhoff Marie Helleberg Maj-Brit Nørregaard Kjær Anders Granholm Carl Johan Steensen Hjortsø Thomas Steen Jensen Morten Hylander Møller Peter Buhl Hjortrup Mik Wetterslev Gitte Kingo Vesterlund Lene Russell Vibeke Lind Jørgensen Klaus Tjelle Thomas Benfield Charlotte Suppli Ulrik Anne Sofie Andreasen Thomas Mohr Morten H. Bestle Lone Musaeus Poulsen Mette Friberg Hitz Thomas Hildebrandt Lene Surland Knudsen Anders Møller Christoffer Grant Sølling Anne Craveiro Brøchner Bodil Steen Rasmussen Henrik Nielsen Steffen Christensen Thomas Strøm Maria Cronhjort Rebecka Rubenson Wahlin Stephan Jakob Luca Cioccari Balasubramanian Venkatesh Naomi Hammond Vivekanand Jha Sheila Nainan Myatra Christian Gluud Theis Lange Anders Perner 《Acta anaesthesiologica Scandinavica》2020,64(9):1365-1375
Introduction
Severe acute respiratory syndrome coronavirus-2 has caused a pandemic of coronavirus disease (COVID-19) with many patients developing hypoxic respiratory failure. Corticosteroids reduce the time on mechanical ventilation, length of stay in the intensive care unit and potentially also mortality in similar patient populations. However, corticosteroids have undesirable effects, including longer time to viral clearance. Clinical equipoise on the use of corticosteroids for COVID-19 exists.Methods
The COVID STEROID trial is an international, randomised, stratified, blinded clinical trial. We will allocate 1000 adult patients with COVID-19 receiving ≥10 L/min of oxygen or on mechanical ventilation to intravenous hydrocortisone 200 mg daily vs placebo (0.9% saline) for 7 days. The primary outcome is days alive without life support (ie mechanical ventilation, circulatory support, and renal replacement therapy) at day 28. Secondary outcomes are serious adverse reactions at day 14; days alive without life support at day 90; days alive and out of hospital at day 90; all-cause mortality at day 28, day 90, and 1 year; and health-related quality of life at 1 year. We will conduct the statistical analyses according to this protocol, including interim analyses for every 250 patients followed for 28 days. The primary outcome will be compared using the Kryger Jensen and Lange test in the intention to treat population and reported as differences in means and medians with 95% confidence intervals.Discussion
The COVID STEROID trial will provide important evidence to guide the use of corticosteroids in COVID-19 and severe hypoxia.189.
Toneva Diana H. Nikolova Silviya Y. Tasheva-Terzieva Elena D. Zlatareva Dora K. Lazarov Nikolai E. 《International journal of legal medicine》2022,136(6):1851-1863
International Journal of Legal Medicine - Sex identification is a primary step in forensic analysis of skeletal remains. The accuracy of sex estimation methods greatly depends on the sexual... 相似文献