全文获取类型
收费全文 | 1351924篇 |
免费 | 115765篇 |
国内免费 | 6563篇 |
专业分类
耳鼻咽喉 | 17163篇 |
儿科学 | 43210篇 |
妇产科学 | 36840篇 |
基础医学 | 186416篇 |
口腔科学 | 36574篇 |
临床医学 | 121843篇 |
内科学 | 281496篇 |
皮肤病学 | 32366篇 |
神经病学 | 111644篇 |
特种医学 | 56712篇 |
外国民族医学 | 274篇 |
外科学 | 212378篇 |
综合类 | 31593篇 |
现状与发展 | 5篇 |
一般理论 | 423篇 |
预防医学 | 107124篇 |
眼科学 | 28530篇 |
药学 | 95023篇 |
5篇 | |
中国医学 | 2419篇 |
肿瘤学 | 72214篇 |
出版年
2018年 | 13920篇 |
2017年 | 11077篇 |
2016年 | 13456篇 |
2015年 | 15277篇 |
2014年 | 20967篇 |
2013年 | 30881篇 |
2012年 | 37963篇 |
2011年 | 40423篇 |
2010年 | 25285篇 |
2009年 | 24655篇 |
2008年 | 37367篇 |
2007年 | 39741篇 |
2006年 | 40722篇 |
2005年 | 39163篇 |
2004年 | 37272篇 |
2003年 | 36312篇 |
2002年 | 34224篇 |
2001年 | 66271篇 |
2000年 | 68085篇 |
1999年 | 56709篇 |
1998年 | 16787篇 |
1997年 | 15065篇 |
1996年 | 16043篇 |
1995年 | 16259篇 |
1994年 | 15121篇 |
1993年 | 14177篇 |
1992年 | 47128篇 |
1991年 | 45772篇 |
1990年 | 43992篇 |
1989年 | 41846篇 |
1988年 | 38773篇 |
1987年 | 38105篇 |
1986年 | 35873篇 |
1985年 | 34647篇 |
1984年 | 26366篇 |
1983年 | 22116篇 |
1982年 | 13854篇 |
1981年 | 12460篇 |
1980年 | 11725篇 |
1979年 | 23558篇 |
1978年 | 17080篇 |
1977年 | 14394篇 |
1976年 | 13193篇 |
1975年 | 13731篇 |
1974年 | 16097篇 |
1973年 | 15402篇 |
1972年 | 14175篇 |
1971年 | 13039篇 |
1970年 | 11885篇 |
1969年 | 11103篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
131.
Mt D. Dbrssy Chockalingam Ramanathan Danesh Ashouri Vajari Yixin Tong Thomas Schlaepfer Volker A. Coenen 《The European journal of neuroscience》2021,53(1):89-113
Deep brain stimulation (DBS) in psychiatric illnesses has been clinically tested over the past 20 years. The clinical application of DBS to the superolateral branch of the medial forebrain bundle in treatment‐resistant depressed patients—one of several targets under investigation—has shown to be promising in a number of uncontrolled open label trials. However, there are remain numerous questions that need to be investigated to understand and optimize the clinical use of DBS in depression, including, for example, the relationship between the symptoms, the biological substrates/projections and the stimulation itself. In the context of precision and customized medicine, the current paper focuses on clinical and experimental research of medial forebrain bundle DBS in depression or in animal models of depression, demonstrating how clinical and scientific progress can work in tandem to test the therapeutic value and investigate the mechanisms of this experimental treatment. As one of the hypotheses is that depression engenders changes in the reward and motivational networks, the review looks at how stimulation of the medial forebrain bundle impacts the dopaminergic system. 相似文献
132.
Gordon K. B. Saburov V. O. Koryakin S. N. Gulidov I. A. Fatkhudinov T. Kh. Arutyunyan I. V. Kaprin A. D. Solov’ev A. N. 《Bulletin of experimental biology and medicine》2022,173(2):281-285
Bulletin of Experimental Biology and Medicine - Fast neutron therapy, which previously has demonstrated effective results, but along with a large number of complications, can again be considered a... 相似文献
133.
Denise Lee Marcella D. Walker Hsin Yi Chen John A. Chabot James A. Lee Jennifer H. Kuo 《Surgery》2019,165(1):107-113
Background
Bone mineral density (BMD) has been found to improve after parathyroidectomy (PTX) in patients with primary hyperparathyroidism. There are few data on the effect of PTX on BMD in normocalcemic and normohormonal primary hyperparathyroidism.Methods
A retrospective analysis of 92 primary hyperparathyroidism patients who underwent PTX between 2004 and 2012 with pre- and post-PTX dual-energy x-ray absorptiometry was performed. Within-person changes in BMD pre- and post-PTX were analyzed using log linear mixed models, stratified by biochemical status.Results
Bone mineral density increased post-PTX in the whole cohort at the lumbar spine (+2.5%), femoral neck (+2.1%), and total hip (+1.9%) and decreased at the one-third radius (–0.9%). On comparison of BMD changes by profile, BMD increased in those with the typical profile at the lumbar spine (3.2%), femoral neck (2.9%), and total hip (2.9%) but declined at the one-third radius (–1.5%). In contrast, BMD improved only at the femoral neck (4.3%) in the normohormonal group and did not change at any site in the normocalcemic group. The typical group had a greater increase in BMD over time at the femoral neck and total hip compared with normocalcemic patients.Conclusion
Our results indicate that the skeletal benefit of PTX was attenuated in normocalcemic and normohormonal patients, suggesting that skeletal changes after PTX may depend on biochemical profile. 相似文献134.
135.
136.
137.
Toshiro Hara Rony Chanoch-Myers Nathan D. Mathewson Chad Myskiw Lyla Atta Lillian Bussema Stephen W. Eichhorn Alissa C. Greenwald Gabriela S. Kinker Christopher Rodman L. Nicolas Gonzalez Castro Hiroaki Wakimoto Orit Rozenblatt-Rosen Xiaowei Zhuang Jean Fan Tony Hunter Inder M. Verma Kai W. Wucherpfennig Itay Tirosh 《Cancer cell》2021,39(6):779-792.e11
138.
139.
O’Beirne Sarah L. Chazen J. Levi Cornman-Homonoff Joshua Carey Bridget T. Gelbman Brian D. 《Lung》2019,197(6):727-733
Lung - Diaphragmatic paralysis (DP) is an important cause of dyspnea with many underlying etiologies; however, frequently no cause is identified despite extensive investigation. We hypothesized... 相似文献
140.
Tarandovskiy Ivan D. Rajabi Ali A. Karnaukhova Elena Buehler Paul W. 《Journal of thrombosis and thrombolysis》2019,48(1):81-87
Journal of Thrombosis and Thrombolysis - C1-inhibitor (C1INH) was shown to enhance thrombin generation (TG) in the presence of thrombomodulin (TM) by reducing production of activated protein C.... 相似文献