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21.
22.
Zhang Ying-lin张应霖 Liao Da-mei廖大美 Wei Yong-gui魏永贵and Bai Guo-rong白国荣Luzhou Medical College Sichuan 《中华医学杂志(英文版)》1987,100(1):56-57
In 1980, 267 patients with related symp-
toms were examined by tomography in our hos-
pital. Among them the styloid process (SP) of
128 cases were 30 mm or more in length. Pha-
ryngeal palpation was performed in 98. The SPs
of 61 patients were palpable and tender. Diagno-
sis was based on the related symptoms, tomogra-
phy, positive pharyngeal palpation and SP tender-
ness. Tomography showed that the longest SP
was 75 mm, while the longest one with symptoms
was 65 mm. The medial angulations of the SPs
were from 100 t0 27° and the anterior angulations
from 300 t0 50°. 相似文献
23.
牛骨形成蛋白在骨不连中的临床应用 总被引:2,自引:0,他引:2
应用牛骨形成蛋白(bovineBoneMorphogeneticProtein简称b-BMP)成功的治愈13例骨不连病人。经过13个月~29个月随访观察,效果较好。本组病人术前平均已做过1.5次手术。13例病人中,有12例被1次治愈。1例病人再次行内固定加用牛骨形成蛋白的植入也被治愈。骨形成蛋白的应用方式,采用同锻石膏复合后植入骨不连处。平均每个病人植入100mgBMP,13例病人平均治愈时间为4.7个月。术后没有任何并发症。 相似文献
24.
竹荪深层发酵菌丝体对小鼠免疫功能的影响及其抗肿瘤作用 总被引:12,自引:0,他引:12
过对食药用真菌──竹荪深层发酵菌丝体提取液对小鼠免疫功能及S-180肿瘤细胞的作用观察,表明其发酵菌丝体可明显提高小鼠腹腔巨噬细胞的吞噬功能(P<0.01),并显著增加免疫器官的重量(P<0.05);对小鼠S-180肿瘤的抑瘤率为40.63%。 相似文献
25.
本文对以重组淋球菌IgA蛋白酶为抗原制备的7株特异性McAb的特性进行了初步研究。结果有5株(1C8、1E5、1F11、1G3和2E6)能中和淋球菌IgA蛋白酶活性。经相加试验初步证明,其中1F11、2G3与其它3株McAb的作用位点不同。因此,淋球菌IgA蛋白酶至少存在3个中和表位。 相似文献
26.
气管与主支气管肿瘤的影像诊断(附32例报告) 总被引:5,自引:1,他引:4
作者对32例经病理证实的气管与主支气管良、恶性肿瘤的影像学表现进行分析,归纳为3型:腔内型、壁增厚型和腔内外型。后2种类型提示恶性,而无蒂的腔内型表现者不能鉴别良,恶性。作者还评价了常规体层、CT及MRI诊断气管与主支气管肿瘤的优、缺点,讨论了影像诊断的作用。 相似文献
27.
In rabbit platelet rich plasma (PRP), 5-hydroxytraptamine (5-HT,0.03~3μmol/L) induced decrease in light transmission (DLT) dose-de pendently with centralization, as revealed by electron microscopy. However, 5-HT did not induced platelet aggregation and release reaction. 5-HT-induced DLT was inhibited by methysergide (0.3~30μmol/L), indomethacin (0.3~10μmol/L) and PGE_1 (0.01~0.3μmol/L) in a dose-dependent manner, but not EGTA(0.3~3mmol/L). Collagen(Coll), arachidonic acid (AA), adenosine diphosphate (ADP) and a stable thromboxane A2 analoge(STA_2) also induced DLT before aggregation by themselves, which was also inhibited by PGE_1, but not inhibited by EGTA except for Coll However,Coll-, AA-, STA_2-and ADP-induced DLT were reduced by pretreatment of PRP with 5-HT dose-depen-dently. The duration of DLT by Coll and AA were decreased from 151.4±5.93 sec and 15(?)38±0.60sec to 45.44±4.04 sec and 9.00±1.25 sec respectively ((?)±s(?) P<0.01), but not by ADP and STA_2, 3μmol/L of ADP-and 0.3μmol/L of STA_2-induced aggregation which was not accompanied with release reaction were enhanced by 5-HT pretreatment, but in those (Coil 5μg/ml, AA 100~200μmol/L and STA_2 1~3 μmol/L) with release reaction, the amount of adenosine triphosphate(ATP)were suppressed significantly (P<0.001) by 5-HT pretreatment without the effect on the magnitude of aggregation, The mobilization of cytosolic free calcium concentration ([Ca~(2+)]i) was observed after 5-HT treatment in single washed platelet, the results indicated that the basic level of [Ca~(2+)] i was 64.78±3.24nmol/L and this level was increased dose-dependently and significantly at 30 sec after administration of 5-HT and the time of peak value of [Ca~(2+)] i was at 90~100 sec.The similar time courses of suppression of ATP released during aggregation, in cases of Coll(5μg/ml), AA (200μmol/L) and STA_2(3μmol/L), by 5-HT were also found in the present experiment. 相似文献
28.
腰椎峡部裂的CT诊断 总被引:12,自引:2,他引:10
目的:回顾性分析腰椎峡部裂的CT表现并讨论其诊断与鉴别诊断,材料与方法,23例患先行腰椎侧位扫描定位图像,采用与椎间盘平行的角度,自病变脊椎的上一椎体下缘边续发描至于下椎体上缘,层厚4或5mm必要时在峡部行2mm,层厚扫描,结果;23例中,累及双侧21例,单侧2例,发生在L516例,L47例,CT表现为同一脊椎关节突间的低密度裂隙,出瑞椎弓根下缘平面,走行不规则,裂隙可宽可窄,表面不光滑。 相似文献
29.
30.
Dolastatin 10, a cytostatic peptide containing several unique amino acid subunits, was isolated from the marine shell-less mollusk Dolabella auricularia (Pettit GR, Kamano Y, Herald CL, Tuinman AA, Boettner FE, Kizu H, Schmidt JM, Baczynskyj L, Tomer KB and Bontems RJ, J Am Chem Soc 109: 6883-6885, 1987). Since our preliminary studies demonstrated that dolastatin 10 inhibited tubulin polymerization and the binding of radiolabeled vinblastine to tubulin, an initial characterization of the properties of dolastatin 10 included a comparison to other antimitotic drugs interfering with vinca alkaloid binding to tubulin (vinblastine, maytansine, rhizoxin, and phomopsin A). Dolastatin 10 inhibited the growth of L1210 murine leukemia cells in culture, with a concordant rise in the mitotic index, and its IC50 value for cell growth was 0.5 nM. Comparable values for the other drugs were 0.5 nM for maytansine, 1 nM for rhizoxin, 20 nM for vinblastine, and 7 microM for phomopsin A. IC50 values were also obtained for the polymerization of purified tubulin in glutamate: 1.2 microM for dolastatin 10, 1.4 microM for phomopsin A, 1.5 microM for vinblastine, 3.5 microM for maytansine, and 6.8 microM for rhizoxin. Dolastatin 10 and vinblastine were comparable in their effects on microtubule assembly dependent on microtubule-associated proteins. Preliminary studies indicated that dolastatin 10, like vinblastine, causes formation of a cold-stable tubulin aggregate at higher drug concentrations. We confirmed that rhizoxin, phomopsin A, and maytansine also inhibit the binding of radiolabeled vinblastine and vincristine to tubulin. Dolastatin 10 and phomopsin A were the strongest inhibitors of these reactions, and rhizoxin the weakest. Dolastatin 10, phomopsin A, maytansine, vinblastine, and rhizoxin all inhibited tubulin-dependent GTP hydrolysis. The greatest inhibition of hydrolysis was observed with dolastatin 10 and phomopsin A, and the least inhibition with rhizoxin. 相似文献