全文获取类型
收费全文 | 676篇 |
免费 | 41篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 20篇 |
妇产科学 | 16篇 |
基础医学 | 73篇 |
口腔科学 | 53篇 |
临床医学 | 52篇 |
内科学 | 144篇 |
皮肤病学 | 11篇 |
神经病学 | 24篇 |
特种医学 | 18篇 |
外科学 | 82篇 |
综合类 | 8篇 |
预防医学 | 79篇 |
眼科学 | 18篇 |
药学 | 70篇 |
中国医学 | 7篇 |
肿瘤学 | 38篇 |
出版年
2023年 | 9篇 |
2022年 | 17篇 |
2021年 | 18篇 |
2020年 | 17篇 |
2019年 | 24篇 |
2018年 | 35篇 |
2017年 | 14篇 |
2016年 | 27篇 |
2015年 | 22篇 |
2014年 | 40篇 |
2013年 | 45篇 |
2012年 | 51篇 |
2011年 | 68篇 |
2010年 | 31篇 |
2009年 | 26篇 |
2008年 | 31篇 |
2007年 | 44篇 |
2006年 | 25篇 |
2005年 | 27篇 |
2004年 | 24篇 |
2003年 | 17篇 |
2002年 | 15篇 |
2001年 | 4篇 |
2000年 | 11篇 |
1999年 | 8篇 |
1998年 | 5篇 |
1997年 | 4篇 |
1995年 | 4篇 |
1994年 | 2篇 |
1992年 | 3篇 |
1991年 | 2篇 |
1990年 | 6篇 |
1989年 | 5篇 |
1988年 | 4篇 |
1987年 | 3篇 |
1986年 | 3篇 |
1985年 | 5篇 |
1984年 | 5篇 |
1983年 | 4篇 |
1979年 | 1篇 |
1978年 | 1篇 |
1976年 | 1篇 |
1974年 | 1篇 |
1973年 | 1篇 |
1971年 | 1篇 |
1970年 | 1篇 |
1969年 | 1篇 |
1968年 | 1篇 |
1967年 | 2篇 |
1966年 | 1篇 |
排序方式: 共有719条查询结果,搜索用时 31 毫秒
51.
Breast Cancer Risk From Modifiable and Non-Modifiable Risk Factors among Palestinian Women: A Systematic Review and Meta-Analysis
下载免费PDF全文
![点击此处可从《Asian Pacific journal of cancer prevention》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Heba Mohammed ArafatJulia OmarRosediani MuhamadTengku Ahmad Damitri Al-AstaniNoorazliyana ShafiiNahed Ali Al LahamIhab NaserOhood Mohammed ShamallakhKholoud Mohammed ShamallakhMajed Abed Al Rahman Jebril 《Asian Pacific journal of cancer prevention》2021,22(7):1987-1995
Objective: Breast cancer (BC) is known as one of the deadliest forms of cancer, and it is increasing globally. Identifying risk factors for BC is a key point in developing preventive strategies to reduce its occurrence. Herein, we aimed to conduct a systematic review and meta-analysis focus on the risk factors for BC in Palestine. Material and Methods: We performed a systematic search via PubMed, MEDLINE, SCOPUS, Science Direct, Cochrane library, Emerald Insight, and Google scholar for identifying studies published on BC risk factors up to March 2021. Pooled odds ratios (OR) are calculated using fixed and random-effect models. Data were processed using Review Manager 5.4 (RevMan 5.4). Results: From a total of 73 articles, seven case-control studies met the criteria for systematic review. Meta-analysis results showed that of the known modifiable risk factors for BC, diabetes mellitus (DM) had the highest odds ratio (OR = 4.97, 95% CI 3.00- 8.25) followed by hypertension (OR = 3.21, 95% CI 1.96-5.23), obesity (BMI >30 Kg/m2) (OR = 2.90, 95% CI 2.00- 4.21), and passive smoking (OR = 1.50, 95% CI 1.12- 2.02). Controversially, breastfeeding (OR = 0.37, 95% CI 0.23- 0.61) was protective factor in BC. Of non-modifiable risk factors for BC has reached menopause had the highest odds ratio (OR = 3.74, 95% CI 2.64- 5.29), followed by family history of BC (OR = 2.63, 95% CI 1.07-6.44) and age (≥ 40 years) (OR = 2.49, 95% CI 1.43-4.34). Conclusions: The most significant predictors of BC in Palestine were DM, hypertension, passive smokers, age (>40), reached menopause, and family history of BC. Almost all these risk factors are consistent with known risk factors for breast cancer in other parts of the world. 相似文献
52.
Mona A. Abed Nidal F. Eshah Debra K. Moser 《Heart & lung : the journal of critical care》2018,47(3):226-230
Background
In developing countries, the number of adults who develop myocardial infarction (MI) at a young age is high. The popularity of waterpipe smoking (WPS) has increased among the same age group. It is unknown if WPS contributes to the incidence of early-onset MI.Objective
To study the association of WPS with early-onset MI, which is defined as first MI occurring in individuals 18 ≥ age ≤ 45 years compared to those older than 45 years.Methods
This was a cross-sectional study. The association of WPS with first-time MI was compared between younger and older adults (N = 225).Results
Twenty-five percent of all participants developed an acute MI before the age of 46 years. Both cigarette and WPS were more common among younger first-time MI patients than older first-time MI patients.Conclusions
WPS is one risk factor that distinguishes the risk profile of young adults with early-onset MI. 相似文献53.
Soumeya Abed Alisa Tubsuwan Porntip Chaichompoo In Hyun Park Alice Pailleret A?ssa Benyoucef Lucie Tosca Edouard De Dreuzy Anais Paulard Marine Granger-Locatelli Francis Relouzat Stéphane Prost Gerard Tachdjian Suthat Fucharoen George Q. Daley Emmanuel Payen Stany Chrétien Philippe Leboulch Le?la Maouche-Chrétien 《Haematologica》2015,100(10):e428-e431
54.
Background
Cancer is a serious health problem and the third leading cause of death in the occupied Palestinian territory, both in adults and children. For most children younger than 18 years who have cancer, there is no obvious cause. The aim of this study was to identify the main risk factors for paediatric cancer in the Gaza Strip.Methods
This case-control study was done in five Gaza Strip governorates. We enrolled children diagnosed with paediatric cancer and receiving treatment at oncology departments at Ranteesy Specialised Paediatric Hospital, Al Shifa Hospital, and at the European Gaza Hospital in 2012 and 2013. Controls were children who visited primary health-care centres and matched for locality, age, and sex. We used face-to-face questionnaires to interview the children's parents and χ2 tests for analyses.Findings
292 children were enrolled in this study. 146 children had been diagnosed with paediatric cancer (70 [48%] children had a solid tumour, 50 [35%] had haematological cancer, and 25 [17%] had a lymphoma tumour). 146 children were enrolled as controls. The main risk factors associated cancer were exposure to ultrasound during gestational period (p<0·0001) and family cancer history (p=0·001). For environmental factors, we found associations of paediatric cancer with family history of smoking (p=0·016), exposure in pregnancy to passive smoking (p=0·018), and white phosphorus (p<0·0001). Agriculture pesticides and herbicides were not associated with paediatric cancer. Furthermore, the parents' educational level and occupation and the mother's exposure to x-rays were not associated with paediatric cancer.Interpretation
The study presents data on several potentially avoidable environmental risk factors for paediatric cancer in the Gaza Strip.Funding
None. 相似文献55.
Background
Acute meningococcal septicaemia is a fulminant disease, and mortality and long-term morbidity can be very high if not treated appropriately. We aimed to evaluate case fatality rate of all children admitted with acute meningococcal septicaemia.Methods
We did a retrospective cohort study of all paediatric cases of acute meningococcal septicaemia admitted to Al-Nasser Paediatric Hospital, the largest paediatric hospital in the Gaza Strip. Acute meningococcal septicaemia was diagnosed clinically and confirmed on the basis of results from skin smears and blood cultures, and meningitis was diagnosed clinically and confirmed by bacteriological examination of cerebrospinal fluid. Sociodemographic and clinical data and outcome information were obtained from hospital records. Outcome measures were predicted mortality using Paediatric Risk of Mortality score III (PRISM-III), actual mortality, and standardised mortality ratio (SMR).Findings
Between Jan 1, 2009, and Sept 31, 2015, 240 children were admitted with acute meningococcal septicaemia. 113 (47%) children were boys, and the average age was 3·15 years (SD 2·6). The number of admitted children with acute meningococcal septicaemia decreased from 47–59 cases per year in 2009–11, to 21–22 cases per year in 2012–15. Similarly, there were fewer deaths in 2012–15 (n=14) than in 2009–11 (n=35). The total mortality predicted by PRISM-III was 25·6%, whereas the actual overall mortality was 21% (standardised mortality ratio 0·814; n=49). 41 (82%) children died within 24 h of admission, 69 (29%) children received corticosteroid, 85 (35%) children received inotropic medications, and 46 (19%) children required mechanical ventilation for a median of 24 h (IQR 6–48]. Acute meningococcal septicaemia was associated with meningitis in 75 (31%) children. The most common complications were multiorgan failure (22 [9%] children), skin necrosis or scarring (13 [5%]), convulsions or seizures (13 [5%]), and disseminated intravascular coagulopathy (ten [4%]). Mortality was independently associated with age (odds ratio per 1-year decreased age 1·06, 95% CI 1·03–1·10; p=0·0006), shock (3·83, 1·32–11·70; p=0·015), absence of meningitis on presentation (9·55, 3·25–28·07; p=0·0013), and mechanical ventilation (9·85; 4·31–22·54; p<0·0001).Interpretation
The mortality and morbidity associated with meningococcemia are improving but remain high. Timely identification of acute meningococcal septicaemia in primary care as well as in emergency departments is crucial.Funding
None. 相似文献56.
57.
58.
To review our experience in treatment of patients with thoracic empyema at a teaching hospital chart of patients were retrospectively reviewed over a 72-month period. A total of 112 patients (94 men, 18 women, mean age: 39, range: 6-89 years) underwent therapeutic procedures for thoracic empyema between 2001-2006. The causes of empyema included parapneumonic empyema (60.7%), thoracic trauma (20.5%), surgical procedures (7.1%) and seeding from an extra-pulmonary source (11.7%). Multiloculated empyemas were documented in 45 patients (40%). Insertion of chest tube was the first procedure in 103 patients (92%). Nineteen patients (17%) were treated by thoracotomy, ten patients (8.9%) had fibrinolytic therapy, eight patients (7.2%) underwent video assisted thoracic surgery (VATS) and sixteen patients (14.3%) had subsequent radiologic-guided drainage. Thoracotomy-Decortication was successful in 90% of patients undergoing surgery and the least successful intervention was tube thoracostomy alone. Twelve of 112 patients (10.7%) died in the hospital including one patient in the thoracotomy group. Long-term follow-up was available in 67 patients including all of patients requiring surgery and fibrinolytic therapy. Thirty four patients (50%) obtained complete functional recovery. Simple drainage as the first procedure for the treatment of thoracic empyema has a high failure rate. Selection of a therapeutic option should be based on age, underlying disease, stage of the empyema, state of the loculation, local expertise and availability. Surgical procedures such as VATS or thoracotomy are recommended as the first procedure in elderly patients and advanced empyema. 相似文献
59.
60.