支气管动脉给药治疗难治性肺结核（附10例报告）

难治性肺结核是当前结核专科医院内遇到较多且不好处理的一种肺结核，其特点是病程长，病情重．耐药率高。并发症多，疗效低，预后差，经支气管动脉给药能提高有效血浆浓度从而杀死结核菌，促进病灶愈合。我们近一年来对10例难治性肺结核在常规全身用药的基础上，用异烟肼．环丙杀星经支气管动脉给药，效果明显，现报告如下。     

火针加超短波治疗高原地区周围性面神经炎60例

近年来,笔者根据高原地区面神经炎发病特点,采用火针加超短波治疗该病,取得了满意疗效,现报告如下。1临床资料 本组病例共60例,男39例,女21例;年龄16～58岁;发病时间最短3天,最长60天。临床表现为起病突然,多在睡眠醒来时发现一侧面部板滞、麻木,不能作蹙额、皱眉、鼓颊等动作,口角歪斜,流涎,     

Differentiation of human epidermal stem cells into fibroblasts induced by TGF-β1 in vitro

Objective To investigate the correlation between human epidermal stem cell (hESCs) and hypertrophic scar or keloid. Methods Improved collagen Ⅳ-coated adhesion methods was used to isolate and culture the epidermal stem cells after neutral protease selectively digested the dermo-epidermal junctions. After the cells were cultured and expanded in vitro, and passage 3 hESCs were induced by different concentrations of TGF-β1 (0.1, 5.0, and 10.0 ng/ml). Morphological fea-tures and identification of these cells were meseasured by HE, Masson, immunohistochemical staining on the days 3 and 7, respectively. Results After induced by TGF-β1 for 3 and 7 days, the morpholo-gy of the epidermal stem cell (hESCs) was changed into fusiform shape, similar to fibroblasts. 70 % ofthe cell which was induced by TGF-β1 were blue stained in the cytoplasm by Masson stain, which is the distinctive method for collagen, suggesting collagen appeared or increased in the cells. The collagen concentrations in supernatants of hESCs were 0.4150±0.0014, 0.3380±0. 0020, and 0.3870±0.0020, much higher than that in control group (0.0780±0.0025) and normal skin fibro-blast group (0.15004±0.0051) (P<0.05). Immunohistochemical staining revealed that positive rates of these cells for anti-vimentin staining were more than (95.00±1.20)% in experiments and (5.70±0.20)% in control group. Conclusion The differentiantion of hESCs induced by TGF-β1 into fibro-blasts indicates that hESCs may play a role in the pathogenesis of hypetrophic scar and keloid.     

麻风家内接触者的血清流行病学研究——两年随访

用检测抗ＮＤ－Ｏ－ＢＳＡ抗体的ＥＬＩＳＡ，对初次调查时抗体阳性的２００名健康人和１１９例麻风家庭接触者进行的血清学随访中分别２６．５％和２３．５％仍为阳性；初次检查抗体为阳性，而在第１次随访时阴转者，以及初次检查及第１次随访均阴性的健康人和接触者，在本次随访中又变为阳性的分别为２０．１％－３３．０％的１３．８－３６．０％。     

载人离心机空战动作曲线控制研究及应用

载人离心机是加速度生理研究的必要设备。近年来为适应高性能飞机特点,国外众多报道在载人离心机上进行模拟空战动作的实验。本所的载人离心机只能作单一的梯形加速度曲线,本研究的目的是用计算机控制载人离心机完成各种加速度模式,实现模拟空战动作。载人离心机的加速度是指离心机吊舱的加速度与其重力加速度的矢量和。其值的大小取决于离心机的臂长和转速,在这些因素中,可以调节的只有其转速。又因为转速和控制电压成正比变化,所以我们用电压控制大电机的调速,并作为闭环反馈送入计算机系统。当电机闭环系统给定电压为零时,系统进入准备状态。控制人员从键盘发出执行指令,转速上升,同时进行数据采集处理,作为判别系统运行状态的依据。该系统软件可连续工作,实时记录,判别动态反馈控制数     

小儿氯胺酮麻醉与微量元素铜,锌的变化观察

铜、锌是机体必需的微量元素,其作用日益受到国内外学者的关注。我们采用电位溶出分析法观察小儿氯胺酮麻醉时血清铜、锌的变化,现将初步观察结果总结如下。资料和方法一、临床资料选择 ASA.I,行斜疝和鞘膜积液手术儿童25例,男21,女4例,年龄1.5～6岁。