经鼻内窥镜脑脊液鼻漏修补术

目的 :探讨经鼻内窥镜修补脑脊液鼻漏的操作技巧及疗效。方法 :经鼻内窥镜手术修补脑脊液鼻漏 12例 ,在鼻内窥镜直视下寻找漏口 ,处理漏口周围黏膜 ,应用肌浆、鼻中隔和中鼻甲黏膜瓣、明胶海绵及EC耳脑胶或生物蛋白胶等修补漏口 ,用湿润烧伤膏油纱条填塞鼻腔 ,术后 4～ 10d抽取纱条。结果 :12例脑脊液鼻漏均 1次修补成功。结论 :经鼻内窥镜修补脑脊液鼻漏具有微创、安全、复发率低等优点。     

急性CO中毒后迟发性脑病15例临床分析

一氧化碳中毒迟发性脑病指急性一氧化碳中毒患者经及时治疗临床症状消失后，经数日至数周的“假愈期”又突然出现一系列神经精神障碍。现将我院1999-10—2003-02收治的15例报告如下。     

胃癌高发区卵巢转移性癌临床病理特点

胃癌高发区卵巢转移性癌临床病理特点平金良，祁水琴，董吉顺，杜志奋浙江医科大学湖州市第二教学医院（湖州市３１３０００）我院自１９６３年～１９９２年，收治非女性生殖道来源的卵巢转移性癌２４例，占同期卵巢恶性肿瘤的１６．９％。发病年龄２４～５８岁，平均３６...     

妊娠期及哺乳期乳腺癌31例分析

我科于1989～1993年共收治妊娠期及哺乳期乳腺癌31例,现就其临床特点分析如下: 临床资料     

学生体质模糊综合评价的探讨

学生体质综合评价离不开评价标准的制定。无论是离差法还是百分数法[1]，其划分等级的中界值是一条清晰的界限．在此线上下的微小变化，就会被判为两个不同的等级。相反，某一年龄组中尽管下限和上限的差值较大，但仍属于一个等级，这显然不够合理。群体评价差异就更大。本文运用模糊综合评价法，选用线段函数为隶属度，取得满意结果。1模型与原理1．且选择因素集体重／身高X1000，mZ一肺活量／体重，。13＝503跑．u4一立定跳远，115一引体向上八m卧起坐，tie＝50mX8往返跑，800m跑（女），1000m跑（男）。1．2评价集V一呼等（VI）．中下…     

大鼠摄入铝,氟及其不同比例混合物后血和骨中铝氟含量分析

Wistar rats were divided into 8 groups:control, 300 ppm F, 130 ppm F, 300 ppm Al, 1200 ppm Al, 130 ppm Al + 130 ppm F. 300 ppm Al + 300 ppm F and 1200 ppm Al + 300 ppm F. The chemicals were mixed into the standard diet. The animals were fed on the diets for 12 weeks. Contents of F, Al, Ca and P in the blood (or serum) and humerus were determined at the end of 12 weeks. The results showed that the level of F in the blood and bone in the unadulterated F group was increased, especially F in the bone reached a level more than 10 times that of the control. In the 3 mixture groups, blood F and bone F were lowered, while blood F was restored to normal level, but bone F was not nevertheless, the results showed that Al was in antagonism to the absorption of F. In the unadulterated Al groups, blood and bone Al did not parallel with the amount of Al administered. The level of Al in the median Al group was higher than that of the high Al group. Taking the level of blood and bone Al as a measure, when different doses of Al were administered with F, in the low and median dosage of Al, F was in antagonism to Al absorption, but in case of high dosage of Al, F was in potentiation to Al absorption. In all the experimental groups serum P was elevated, but serum Ca was not disturbed. Bone Ca and P were decreased only in the 3 groups with unadulterated F as well as unadulterated and adulterated high dosage of Al. Mechanism of the nonlinearity of Al absorption vs Al dosage, as well as the dual effect of F on the absorption of Al was proposed.     

粘病毒抵抗基因-1启动子88位点G/T多态性影响乙型肝炎病毒感染的自然转归

目的探讨乙型肝炎病毒（HBV）自限感染和慢性感染与粘病毒抵抗基因-1（MxA）启动子的-88位点G／T单核苷酸多态性的关系。方法收集100例抗-HBs和抗-HBc阳性的HBV自限感染者和340例慢性感染者的外周全血，提出基因组DNA；采用竞争分化聚合酶链反应技术为基础的方法进行MxA-88G／T基因分型；采用单因素Odds ratio和x^2检验等方法进行统计学分析。结果MxA-88G／G基因型（低表达型）检出率为50．2％（221／440），T／T基因型（高表达型）检出率为5．5％（24／440），G／T杂合型检出率为44．3％（195／440）。与慢性感染患者相比，自限感染患者携带较低的G／G基因型（41．0％与52．9%，P〈0．05）、G等位基因（62．5％与75．3％，P〈0．01）和较高的T／T基因型（16．0％与2．4%，P〈0．01）、T等位基因（37．5％与24．7％，P〈0．01），而两者之间的G／T杂合型差异无统计学意义。结论MxA-88G／T基因型能在一定程度上影响HBV感染的自然转归，有望成为临床上HBV感染转归的预测指标。