复方麝香注射液联合脑血肿引流术治疗中老年高血压脑出血疗效观察及费用对比

目的:探讨复方麝香注射液联合微创手术治疗中老年高血压脑出血的临床疗效.方法:将78例接受微创治疗的患者随机分组,两组均采用内科综合治疗.手术对照组在综合治疗基础上加用微创手术进行脑血肿引流;中西医结合组在微创手术治疗后加用复方麝香注射液(10～20 ml/d)静脉滴注1周.结果:中西医结合组显效率(66.67%)、有效率(82.05%)均明显高于手术对照组(46.15%和69.23%,P均<0.05),存活患者日常生活能力也明显优于手术对照组(P<0.05),意识恢复时间明显短于手术对照组(P<0.05),并发症的发生率(15.38%)明显低于手术对照组(38.46%,P<0.01),病死率(5.13%)明显低于手术对照组(10.26%,P<0.01),平均住院天数[(18.29±4.93)d]明显少于手术对照组[(26.23±5.82)d,P<0.05],平均住院费用[(5 916.23±826.39)元]明显少于手术对照组[(8 168.35±1 021.21)元,P<0.05].结论:脑血肿引流术后加用复方麝香注射液治疗中老年高血压脑出血,可降低病死率,减少并发症,降低病残程度,提高生存患者的生活质量,缩短住院时间,降低治疗费用.     

法莫替丁与H1受体拮抗剂联合治疗慢性荨麻疹124例疗效观察

124例单用H1受体拮抗剂治疗疗效差的慢性荨麻疹患，联合应用法莫替丁治疗4周，结果显示临床痊愈率和显效分别为85．4％和10．5％，表明法莫替丁与H1受体拮抗剂联合用于这类H1受体拮抗剂不能奏效的慢性荨麻疹患是一种有效的治疗方法。     

Differentiation of human epidermal stem cells into fibroblasts induced by TGF-β1 in vitro

Objective To investigate the correlation between human epidermal stem cell (hESCs) and hypertrophic scar or keloid. Methods Improved collagen Ⅳ-coated adhesion methods was used to isolate and culture the epidermal stem cells after neutral protease selectively digested the dermo-epidermal junctions. After the cells were cultured and expanded in vitro, and passage 3 hESCs were induced by different concentrations of TGF-β1 (0.1, 5.0, and 10.0 ng/ml). Morphological fea-tures and identification of these cells were meseasured by HE, Masson, immunohistochemical staining on the days 3 and 7, respectively. Results After induced by TGF-β1 for 3 and 7 days, the morpholo-gy of the epidermal stem cell (hESCs) was changed into fusiform shape, similar to fibroblasts. 70 % ofthe cell which was induced by TGF-β1 were blue stained in the cytoplasm by Masson stain, which is the distinctive method for collagen, suggesting collagen appeared or increased in the cells. The collagen concentrations in supernatants of hESCs were 0.4150±0.0014, 0.3380±0. 0020, and 0.3870±0.0020, much higher than that in control group (0.0780±0.0025) and normal skin fibro-blast group (0.15004±0.0051) (P<0.05). Immunohistochemical staining revealed that positive rates of these cells for anti-vimentin staining were more than (95.00±1.20)% in experiments and (5.70±0.20)% in control group. Conclusion The differentiantion of hESCs induced by TGF-β1 into fibro-blasts indicates that hESCs may play a role in the pathogenesis of hypetrophic scar and keloid.     

以高钙性肾病为突出表现的原发性甲状旁腺功能亢进1例

以高钙性肾病为突出表现的原发性甲状旁腺功能亢进１例大连医科大学附属第二医院肾内科（１１６０２３）尹永红麻军患者男，４２岁。以多饮、多尿２年，恶心、呕吐３个月为主诉入院。２年前出现烦渴、多饮，每日饮水量７５００～１００００ｍｌ，多尿、夜尿增多。未介意。...     

松节油合成的杀虫增效剂

杀虫增效剂是指对昆虫没有或者很少有杀虫效果的一类化学品,但当它与某些杀虫剂混合使用,能提高杀虫剂的药效,从而达到减少杀虫剂用量,降低成本,减少环境污染的目的。同时,随着长时间的用药,许多害虫对一些杀虫剂均有不同程度的抗性,加入增效剂也是减少抗性的手段之一。 松节油是松脂加工后得到的萜烯类物质,     

犬环杓后肌电起搏参数

双侧喉返神经(RLN)损伤可致气道梗阻,选择性切除喉内组织或声带外移恢复呼吸功能的几种手术均不太理想。有报道对喉返神经麻痹采用电刺激喉内肌改善喉功能,但电起搏的许多参数尚不清楚,作者介绍一组试验并确定一组参数。将杂种成年犬分成两组,Ⅰ组RLN紧急切断术(对照组),Ⅱ组RLN切断加静脉注射巴夫龙(0.1mg/kg),旨在消除对神经的直接刺激。分离暴露环杓后肌(PCA),将两个特制的针电极间距2mm平行插入PCA,垂直于肌纤维,电极间所产生的椭圆形电场与肌纤维     

经皮腔内动脉扩张术治疗肾血管性高血压的临床应用(附5例报告)

1985年至1987年我们对5例肾动脉狭窄患者施行了经皮腔内肾动脉扩张术(Percutaneors translurninal renal angioplasty PTRA)均获成功,共扩张7支肾动脉8处狭窄。现报告如下。     

腹腔镜在不孕症诊断和治疗中的应用

不孕症是妇科常见病之一。据调查 ,各种原因所致不孕占已婚育龄妇女的 1 0 %～ 1 5 % [1 ] 。近年来 ,随着腹腔镜的广泛应用 ,不孕症诊断率不断提高。我科 2 0 0 1年 6月～ 2 0 0 2年 1 0月用腹腔镜诊断和治疗不孕症 66例 ,现报告如下。1　临床资料1 .1　一般资料不孕症病人 66例 ,年龄 2 4～ 41岁 ,平均 2 8.1岁。其中原发不孕 2 4例 ,占 36 .4% ;继发不孕 42例 ,占 63 .6 %。继发不孕中有人工流产史者 35例 (83 .3 % ) ,自然流产史者 2例 (4.8% ) ,中期妊娠引产史者 2例 (4.8% ) ,药物流产史者1例 (2 .4% ) ,正常分娩史者 2例 (4.8% )。1 …