大动脉炎误诊56例分析

对我科1996-01／2007-12误诊的大动脉炎56例总结分析如下。     

小儿疥疮误诊100例临床分析

疥疮是由疥螨引起的接触性皮肤病,临床多见,误诊率最高的为婴幼儿,占误诊病例的51.43%[1]。我院自2002年以来有100例小儿疥疮误诊,现分析如下。1临床资料本组男52例,女48例,年龄7d~2岁,其中30d内10例,5~8个月40例,病程2周~半年,平均30d。皮损情况:红斑、水疱、丘斑、风团、丘疹     

心理治疗尖锐湿疣恐怖症34例分析

对我科2004-04～2005-08皮肤科门诊心理治疗尖锐湿疣恐怖症34例分析如下. 1 临床资料 1.1 一般资料 本组男25例,女9例,年龄24～45（平均27.5）岁.病程1个月～3 a,平均6个月.初中以上化程度12例,高中以上化程度22例.既往患非淋菌性尿道炎8例,尖锐湿疣4例,淋病5例,有不洁性接触史17例,患均多次就医,反复陈述自己患处的局部变化,要求做各项化验检查,并怀疑结果的真实性.表现出明显的恐怖心理和强迫症状.     

两种方法治疗面部糖皮质激素依赖性皮炎疗效比较

目的研究不同的治疗方法对激素依赖性皮炎的疗效。方法200例患者随机分为观察组（100例）和对照组（100例），观察组采用丹皮酚治疗，对照组采用传统的尿素霜治疗，比较两者的疗效。结果对照组治疗有效率为25％，治疗组治疗有效率为52％，两组结果差异有统计学意义（P〈0．05）。结论应用丹皮酚治疗面部激素依赖性皮炎取得了满意的疗效，值得临床推广应用。     

SD大鼠脊髓损伤后微环境的模拟实验

BACKGROUND: We built Sprague-Dawley rat models with mild, moderate, and severe spinal cord injuries to accord with the spinal cord injury types for basic empirical study, and consequently to further understand the microenvironmental change in Sprague-Dawley rats with spinal cord injury, and to provide help for clinical treatment. OBJECTIVE: To observe the changes in nerve function, pathological manifestation and motor sensory evoked potential in Allen’s models and Sprague-Dawley rats with complete spinal cord transection at different time points after spinal cord injury by simulating the microenviroment in Sprague-Dawley rats. METHODS: A total of 125 healthy adult female Sprague-Dawley rats were selected and randomly divided into group sham operation group, 100 gcf hit potential group (20 g×5 cm), 200 gcf hit potential (20 g×10 cm), 300 gcf hit potential group (20 g×15 cm), and spinal cord complete transection group with 25 rats in each group. At 1, 5, 7, 14 and 28 days after model establishment, the degree of spinal cord injury was identified by the BBB scores of motion function, motor evoked potential, and pathological section. RESULTS AND CONCLUSION: (1) Totally 24 Sprague-Dawley rats died in the experiment. The death rate and the rate of complications were highest in the spinal cord complete transection group. The BBB score of each group was decreased. The BBB scores in every group increased as time went on. There were significant differences between each surgery group and the sham operation group at corresponding time points (P < 0.05).  No significant difference was found between the 300 gcf hit potential group and the spinal cord complete transection group at corresponding time points (P > 0.05). (2) In each surgery group, the infiltration of inflammatory cells and obvious swelling of neurons were visible at 1 day after injury. Neural cells reduced with time prolonged. At 28 days after injury, a large number of astrocytes proliferated, scar and spinal cord cavity formed. Above symptoms were worse in the 300 gcf hit potential group and spinal cord complete transection group than in the 100 gcf and 200 gcf hit potential groups. (3) Significant differences in amplitude and latency were detectable between each surgery group and the sham operation group (P < 0.05). No significant difference in amplitude and latency was detected between the 300 gcf hit potential group and the spinal cord complete transection group at corresponding time points (P > 0.05). Results confirmed that hit potential of 20 g×5 cm, 20 g×10 cm and 20 g×15 cm can simulate the microenvironment of Sprague-Dawley rats with mild, moderate and severe spinal cord injury. The rate of complication was lower in modified Allen’s model of different hit potentials than in models of spinal cord complete transection, and was more accorded with basic research.       

Carnation 33光子治疗仪治疗带状疱疹疗效观察

目的：探讨光子治疗仪治疗带状疱疹的治疗效果。方法：选择经临床诊断为带状疱疹的住院病人243例随机分为对照组、氮-氖激光组（He-Ne）、红光组。He-Ne组和红光组在常规药物治疗的基础上外用光子治疗仪进行辅助治疗,对照组单纯采用常规药物泛昔洛韦进行治疗,观察各组的疗效。结果：对照组总有效率67%,He-Ne组92%,红光组90%,红光组和He-Ne组的治疗效果与对照组间差异有显著性意义（P〈0.05）。结论：两种物理疗法均提高了带状疱疹的治愈率,而且安全有效,以光子治疗仪操作简单,值得临床使用推广。     

298例伴包皮过长的尖锐湿疣治疗分析

目的:观察包皮环切术、微波和内服中药治疗伴包皮过长的尖锐湿疣的疗效。方法:将298例伴包皮过长的尖锐湿疣患者随机分为Ⅰ、Ⅱ、Ⅲ组。Ⅰ组(n=101)采用包皮环切术、微波和中药治疗,Ⅱ组(n=98)采用包皮环切术、微波治疗,Ⅲ组(n=99)采用微波、中药治疗。结果:Ⅰ组治愈94例(93.06%),复发7例,复发率6.93%;Ⅱ组治愈87例(88.78%),复发11例,复发率11.22%;Ⅲ组治愈71例(71.71%),复发28例,复发率28.28%。3组复发率差异有统计学意义。结论:采用包皮环切术、微波和中药治疗尖锐湿疣可降低复发率,值得临床推广。     

生物共振治疗仪对过敏性紫癜脱敏的疗效观察

目的：探讨生物共振治疗对过敏性紫癜脱敏治疗的临床效果。方法：我们对46例过敏性紫癜患者在基础治疗的同时,加用生物共振治疗仪脱敏治疗,观察临床治疗效果和不良反应。结果：46例,痊愈32例,显效10例,有效2例,无效2例,总有效率95．65％。结论：生物共振治疗仪脱敏治疗过敏性紫癜临床效果好,安全性高,值得临床推广应用。     

不同方式诱导骨髓间充质干细胞的效果比较

背景：以往大多采用转化生长因子β1诱导骨髓间充质干细胞向软骨细胞分化,但诱导效果不佳。目的：对比分析骨髓间充质干细胞与关节软骨细胞共培养诱导、转化生长因子β1诱导骨髓间充质干细胞分化为软骨样细胞的效果。方法：获取SD大鼠关节软骨细胞和骨髓间充质干细胞,分别设置1∶2,1∶1,2∶1浓度组,以转化生长因子β1 诱导组为对照。经诱导培养20 d后MTT法检测细胞活力,阿利新蓝比色法检测氨基聚糖含量,Western Blot检测Ⅱ型胶原蛋白表达。结果与结论：转化生长因子β1组的吸光度值显著小于软骨细胞和骨髓间充质干细胞1∶1组和软骨细胞和骨髓间充质干细胞2∶1组(P < 0.05)。转化生长因子β1组的氨基聚糖含量和Ⅱ型胶原蛋白表达显著低于软骨细胞和骨髓间充质干细胞(1∶2,1∶1,2∶1)组。软骨细胞和骨髓间充质干细胞1∶1组与软骨细胞和骨髓间充质干细胞2∶1组之间各指标比较差异无显著性意义(P > 0.05)。结果表明关节软骨细胞与骨髓间充质干细胞共培养,可使骨髓间充质干细胞向软骨细胞分化,且骨髓间充质干细胞对软骨细胞诱导存在饱和现象。中国组织工程研究杂志出版内容重点：干细胞;骨髓干细胞;造血干细胞;脂肪干细胞;肿瘤干细胞;胚胎干细胞;脐带脐血干细胞;干细胞诱导;干细胞分化;组织工程