腓肠肌血肿的诊断及与深静脉血栓的鉴别

腓肠肌血肿与小腿深静脉血栓的临床表现有时颇为相似，且后者具有较高的发病率，因而，临床上误将腓肠肌血肿诊断为深静脉血栓造成误治的现象屡见不鲜。为此，笔者就诊治的13例腓肠肌血肿的临床资料总结如下。     

下肢动脉缺血性患者假性高压的鉴别及临床意义

Objective To evaluate the diagnosis of and management for pseudo-high blood pressure in patients with lower limb ischemia. Methods From March 2006 to March 2007, 182 cases with lower limb ischemia were admitted, and they were divided into three groups. In group 1 pseudo-high blood pressure did not exist, in group 2, patients had pseudo-high blood pressure with ABI<1.3, in group 3, patients had pseudo-high blood pressure and with ABI≥1.3. ABI and TBI were compared with color Doppler, angiography, MRA and CTA. Results In all those 182 patients, there were 102(56.0%)cases having no pseudo-high blood pressure, and 27.5% with concomitant diabetes. Seventy-two cases(39.6%) had pseudo-high blood pressure (ABI<1.3) with 44.4% having diabetes. Eight cases (4.4%) (ABI≥ 1.3) manifested pseudo-high blood pressure with the ratio concomitant diabetes being 75%. Conclusions In diabetic patients with lower limb's ischemia there is increased ratio of pseudo-high blood pressure.     

增殖相关核抗原的研究进展

增殖相关核抗原的研究进展临床学院普外科杨培，综述，罗亿治，审校中国分类号Ｒ７３５．７细胞动力学的研究对深入了解细胞生长、损伤后组织的修复认识及恶性肿瘤的发生、发展等有很重要的意义。分化受阻而生长失去抑制是恶性肿瘤细胞的特征之一。研究表明：在许多类型肿...     

腹腔镜肾部分切除术治疗T1期肾门肿瘤的临床研究

目的探讨腹腔镜肾部分切除术治疗T1期肾门肿瘤的经验。方法回顾2004年6月至2013年6月腹腔镜肾部分切除术治疗12例T1期肾门肿瘤,肾门肿瘤定义为距离肾门血管或肾脏集合系统小于5 mm的肾肿瘤。其中左侧7例、右侧5例,平均年龄58岁(46~72岁),肿瘤直径平均3.6 cm(2.4~7 cm),观察临床疗效。结果全部患者顺利完成手术。平均手术时间80 min(50~140 min),平均热缺血时间28 min(18~45 min),术中平均出血量127 ml(50~340 ml)。术后迟发性出血2例,漏尿1例,术后住院时间平均7.2天(5~14天)。术后病理透明细胞癌8例,嫌色细胞癌2例,血管平滑肌脂肪瘤2例。随访5~48月,2例复发。全部患者术后肾功能正常。结论腹腔镜肾部分切除术治疗T1期肾门肿瘤可行,熟练的腹腔镜技术和术者的临床经验对于成功开展该治疗具有重要作用。     

基于系统药理学的雷公藤配伍甘草治疗类风湿性关节炎作用机制研究

目的 基于系统药理学方法研究雷公藤配伍甘草治疗类风湿性关节炎作用机制。方法 基于中药系统药理学平台（TCMSP）数据库和文献搜索,建立雷公藤配伍甘草化学成分库。运用DRAR-CPI、中医分子机制的生物信息学分析工具（BATMAN-TCM）等在线预测网站,预测成分靶标,并与疾病靶标取交集得到雷公藤配伍甘草治疗类风湿性关节炎作用靶标。通过作用靶标反向筛选潜在活性成分,并用超高效液相色谱-飞行时间质谱（UPLC-Q-TOF/MS）分析手段对活性成分进行验证。利用GeneMANIA数据库搜索间接靶标并利用蛋白互作筛选关键靶标,采用分子对接技术（SystemsDock）对潜在活性成分和关键靶标进行匹配,验证前期靶标筛选的可靠性以及反向药效团匹配的正确性。通过GO和京都基因与基因组百科全书通路分析（KEGG）生物学注释分析关键作用通路,探讨雷公藤配伍甘草治疗类风湿性关节炎作用机制。结果 共得到33个化学成分和47个潜在靶标,其中32个成分31个靶标和35条通路与药对治疗类风湿性关节炎有密切关系,主要涉及花生四烯酸代谢通路、白介素（IL）-17信号通路、核因子（NF）-κB信号通路等炎症通路以及T细胞受体信号通路、C型凝集素受体信号通路等与免疫相关的通路。结论 雷公藤配伍甘草治疗类风湿性关节炎主要通过炎症与免疫调节等多条途径得以实现。     

包皮环扎术600例报告

目的 探讨包皮环扎术的临床应用.方法 应用包皮环扎器治疗包茎及包皮过长600例.结果 随访456例,平均脱环时间14.5天.包皮切缘光滑,柔软,整齐,自然上翻.讨论包皮环扎术适宜治疗各年龄段包茎、包皮过长.     

下肢动脉缺血性患者假性高压的鉴别及临床意义

Objective To evaluate the diagnosis of and management for pseudo-high blood pressure in patients with lower limb ischemia. Methods From March 2006 to March 2007, 182 cases with lower limb ischemia were admitted, and they were divided into three groups. In group 1 pseudo-high blood pressure did not exist, in group 2, patients had pseudo-high blood pressure with ABI<1.3, in group 3, patients had pseudo-high blood pressure and with ABI≥1.3. ABI and TBI were compared with color Doppler, angiography, MRA and CTA. Results In all those 182 patients, there were 102(56.0%)cases having no pseudo-high blood pressure, and 27.5% with concomitant diabetes. Seventy-two cases(39.6%) had pseudo-high blood pressure (ABI<1.3) with 44.4% having diabetes. Eight cases (4.4%) (ABI≥ 1.3) manifested pseudo-high blood pressure with the ratio concomitant diabetes being 75%. Conclusions In diabetic patients with lower limb's ischemia there is increased ratio of pseudo-high blood pressure.     

论TASC分型与下肢动脉硬化闭塞的治疗选择

周围动脉闭塞性疾病(peripheral arterial occlusive disease,PAOD)通常指周围动脉硬化性闭塞症,是由于动脉粥样硬化导致动脉狭窄、闭塞引起的缺血性疾病,常见于下肢.     

论TASC分型与下肢动脉硬化闭塞的治疗选择

周围动脉闭塞性疾病(peripheral arterial occlusive disease,PAOD)通常指周围动脉硬化性闭塞症,是由于动脉粥样硬化导致动脉狭窄、闭塞引起的缺血性疾病,常见于下肢.     

Dieulafoy病致上消化道大出血3例报告

Ｄｉｅｕｌａｆｏｙ病临床较为少见 ,常以突发的上消化道大出血就诊。因缺乏典型的病史和体征 ,术前很难做出确定性诊断。当合并消化性溃疡或肝硬化门脉高压时 ,更易误诊、漏诊。近年来我院共收治 3例 ,现报告如下。1　临床资料例 1 ,男 ,52岁。因反复呕血、便血 2 0天入院。 1 6天前因内科治疗无效在外院诊断为十二指肠球部溃疡出血 ,行胃大部切除术。术后仍反复出现呕血、黑便。胃镜检查见胃内大量鲜血及血凝块 ,无法判断出血来源。急诊手术纵行切开胃前壁 ,见胃后壁距贲门 3ｃｍ处黏膜有 0 5ｃｍ隆起、糜烂 ,去除血凝块后有喷射性出血。…