赤子爱胜蚯蚓体液中几种抗菌成分的比较研究

目的对赤子爱胜蚯蚓体液纯化的几种抗菌组分进行比较研究。方法将蚯蚓体液分别经反相柱、分子筛和阴离子交换柱色谱后 ,得到相应活性组分 ,用分光光度法、甲基红四唑 /吩嗪二甲基硫酸盐 (MTS/PMS)比色分析法和双层琼脂抑菌圈法进行抗菌活力筛选。结果在被检测的 3种色谱组分中 ,只有分子筛色谱组分对巨大芽孢杆菌有抗菌活力 ;阴离子交换柱色谱组分对铜绿假单胞菌的抗菌活力最大。其它色谱组分也有一定抗菌活力。结论MTS/PMS比色分析法和双层琼脂抑菌圈法相结合 ,能为纯化和筛选新的抗菌成分提供一个良好的实验平台。     

左上肺Ⅲ期周围型鳞癌的诊治

在12年期间,手术治疗44例右上肺Ⅲ期周围型鳞癌病人。发现右上肺阴影到确诊时间平均为2个月。全部病人接受了右上肺切除,右纵隔淋巴结清扫,其中4例作了袖式切除,支气管成形术。P—TNM分期:Ⅲ_a期23例,Ⅲ_b期21例。术后并发症发生率20.4％(9例)。全组术后第一年生存率为61％(27/44例),Ⅲ_b期无1例活过3年。Ⅲ_a期术后3、5年生存率分别为65.2％(15/23例)及21.7％(5/23例)。对这组病例的特点,延误诊原因及术中、术后处理进行了讨论,认为对Ⅲ_a期病例应积极手术治疗,对Ⅲ_b期病人作肿瘤姑息性切除,主要为了缓解症状。     

香茅醛对淡色库蚊空间驱避效果的观察

在室内研究了香茅醛及混配药剂对蚊虫的驱避、击倒、灭杀效果。结果表明:香茅醛的剂量在400mg以上时,对蚊虫有驱避作用;在700mg时,对蚊虫的击倒、灭杀效果最佳,分别达到了60%和40%;混配药剂处理中,当香茅醛、富右旋反式丙烯菊酯、右旋丙炔菊酯的剂量分别均为100mg时无驱避效果;当剂量分别为300mg、300mg、200mg时,对蚊虫的击倒、灭杀效果最佳,在7h后分别达到了30%和20%,在16h后则达到了60%和40%。     

DIAGNOSIS AND TREATMENT OF STAGE-Ⅲ PERIPHERAL SQUAMOUS CELL CARCINOMA OF RIGHT UPPER LUNG

During a 12-year period, 44 patients were surgically treated for stage- Ⅲ penpberal squamous cell carcinoma of the right upper lobe. The mean time from the discovery of the shadow in the right upper lobe to the confirmation of the diagnosis was 2 months. All patients underwent the resection of the right upper lobe with the dissection of the right mediastinal lymph nodes, among them, 4 patients had sleeve lohectomy of the tight upper lobe. P-TNM staging: 23 cases were in stage-Ⅲ a, 21 cases in stage-Ⅲ b. The frequency of the postoperative complications was 20. 4%(9/44 cases). The 1-year survival rate of all patients was 61% (27/44 cases). None of stage -Ⅲb patients lived longer than 3 years. The postoperative 3-and 5-year survival rates of stage-Ⅲa cases were 65. 2% (15/23cases) and 21.7%(5/23 cases) respectively. In this article, the patients‘ clinical features, the causes of delayed-diagnosis, the operative and postoperative management were discussed. We suggest that the stage-Ⅲa patients should be given surgical treatment,whereas, for the patients of stage-Ⅲ b, palliative operation was given lust for the purpose of reliving the symptoms.     

几种菊酯类药剂对淡色库蚊熏杀效果的研究

在室内研究了3种菊酯类药剂对蚊虫的熏倒、灭杀效果。结果表明:当富右旋反式丙烯菊酯浓度为600mg/mL时驱避效果最佳,对志愿者的有效保护时间为7·5h。药剂浓度为200mg/mL时以右旋丙炔菊酯的击倒、灭杀效果最佳,在16h后分别达到了33·3%、20%,当浓度为400mg/mL、600mg/mL时以富右旋反式丙烯菊酯的效果最佳,16h后对蚊虫的击倒、灭杀效果分别达到50%、23·3%和60%、33·3%。混配药剂中,以富右旋反式丙烯菊酯、右旋丙炔菊酯组合剂量均为300mg/mL时最佳,其对志愿者的有效保护时间为6·5h。16h后对蚊虫的击倒和灭杀效果达到了60%和40%。