硫酸阿托品眼膏和硫酸阿托品眼用凝胶联用于儿童散瞳检影的临床观察

目的研究硫酸阿托品眼膏和硫酸阿托品眼用凝胶联用对儿童散光检影的有效性,安全性。方法 70例3~11岁的屈光不正儿童。随机分为阿托品眼用凝胶对照组(35例,70眼);阿托品眼膏、阿托品眼用凝胶联用实验组(35例,70眼)分别进行散瞳检影,观察用药过程中对儿童的影响。结果给药4d后,对照组和实验组均能有效地散大瞳孔、去除调节性紧张,实验组能有效的消除单用硫酸阿托品眼膏时角膜表面残留油脂造成的检影干扰,降低单一使用硫酸阿托品眼用凝胶的不良反应。     

支气管镜检查中利多卡因毒性致抽搐1例报道及分析

Objective To increase the knowledge of airway topical anesthesia in lidocaine.Methods We analyzed a lymphoma patient which was induced convulsion by lidoeaine for topical anesthesia in airway,and retrospectively analyses the side-effect and clinical application and pharmacokinetics on the basis of the relevant documents.Results The patient,female,1 9 years old,was in hospital for progressive dyspnea during a month.For right trachelophyma she had accepted right cervical thyroid and superior mediastinum resection a month ago,and postoperatively pathology prompted diffuse large B-cell lymphoma in sub-cervical and anterosuperior mediastinum,lymphocytic thyroiditis.After hospitalization we considered that dyspnea was caused by the lymphoma which relapsed and oppressed the trachea.To establish the diagnosis and assessment the airway's condition the bronchoscopy was been done bedside the support of the high frequency jet ventilator.The liver and renal function were normal inspected by plasma biochemistry preoperative,and the method of airway topical anesthesia was instilling 2%lidocaine.The inferior segment of trachea about 40 mm from eminence was external pressure narrow,and the ITlueous membrane was asperity,and the extreme narrow segment was lip-like which caliber was 4×10 mm that the bronchoscopes could pass it by force.The right and left main bronchus opening was external pressure narrow and the distant part was unobstructed no neoplasm,The whole dosage of lidocaine was 300 mg.The operative procedure was successful and no short breath aggravated,and the SPO2 was above 92%.When the tracheal stent was repaired (about 10 min after the first drip of lidocaine) the patient was obnubilation and tonic seizure.After oral trachea cannula by bronchoscope guidance and assisted ventilation by compressing saccule and diazepam 10 mg IV,the convulsion stopped and the mind was clear 5 min later.The electrocardio-detection prompted that the heart rhythm was sinus rhythm and the HR was 150 times/min during the whole process.After the convulsion stopped the femoral artery plasma concentration of lidocaine was 7.76 mg/L which showed poisoning by lidocaine.Conclusions Lidocaine has been the most frequently used medicine for local anesthesia in flexible bronchoscopy.However,its severe side effects have been reported in clinical application.The primary reason of side effect is extra local absorption of lidocaine.It is the important intervention to increase the safety of bronchoscope which inhibits the local absorption of lidocaine.     

宿迁市新生儿先天性甲状腺功能减退症的筛查结果分析

目的对宿迁市新生儿先天性甲状腺功能减退症(CH)的筛查、诊断、治疗和随访进行总结和分析。方法样品采集用干滤纸血片法,采用时间分辨荧光免疫法检测血斑中促甲状腺素(TSH)。结果对110683名新生儿筛查结果显示,初筛阳性病例64例,确诊57例,总发病率0.51‰。结论先天性CH患儿于新生儿早期体内甲状腺激素已发生异常变化,故可经新生儿期进行筛查,使患儿得到早期诊断和及时治疗,减少残疾儿的发生,提高人口素质。     

职业病防治工作的法制管理

《职业病防治法》的制定和实施，是我国社会主义法制建设中的一项重要工作，同时也是我国卫生事业发展过程中的一件大事。《职业病防治法》是由全国人民代表大会常务委员会制定的法律，适用于中华人民共和国领域内的职业病防治活动，为保护劳动者的健康，进行职业病防治管理提供了法律依据。     

肠结核43例误诊原因分析

肠结核容易误诊和漏诊,现据43例误诊病例,对误诊原因及诊断体会加以分析,旨在探讨误诊原因与减少误诊的对策,提高诊断水平。1 误诊病种分布 我院自1973年1月至1997年12月共确诊肠结核289例,其中43例(15.1％)曾误诊。误诊为慢性阑尾炎9例(20.9％),急性阑尾炎8例(18.6％),消化     

痰标本分离66株不动杆菌药敏分析

目的增强对不动杆菌属的认识,以更好地指导临床应用抗生素. 方法对本院1999年8月1日～2002年7月31日间痰66株不动杆菌进行药敏分析. 结果从绝对数看,本院不动杆菌感染呈逐年明显增多趋势;药敏试验显示不动杆菌对亚胺培南、哌拉西林/他唑巴坦敏感率分别为77.27%和62.12%,对17种常用抗菌药物耐药率均>50%. 结论不动杆菌对所试抗生素均产生不同程度的耐药性,对亚胺培南的耐药性明显高于既往的文献报道.     

杞冬消渴汤加减治疗糖尿病88例

目的观察杞冬消渴汤治疗糖尿病的临床疗效。方法从滋补肝肾、活血化瘀入手,自拟杞冬消渴汤治疗糖尿病100例。结果杞冬消渴汤治疗糖尿病在降糖与改善症状方面均取得较好疗效。结论杞冬消渴汤治疗糖尿病疗效显著。     

成功救治重症高致病性H5N1人禽流感二例

22003 年至今我国确诊人感染高致病性H5N1亚型禽流感30例,经救治成功10例,死亡20例.现将福建省救治成功2例报道如下.     

妇女绝经后骨质疏松腰部疼痛的治疗

目的探讨绝经后妇女无外伤腰背部疼痛与骨质疏松的关系。方法回顾分析2008年6月至2009年6月门诊治疗34例无外伤史绝经后妇女患者出现腰背部疼痛的原因及治疗方法。结果绝经后妇女无外伤史腰背部疼痛患者,腰背部疼痛的原因大多数是由骨质疏松所引起。结论绝经后妇女无外伤史腰背部疼痛的原因大多数是由于骨质疏松所造成,在治疗时应同时进行抗骨质疏松治疗才能收到较好的治疗效果。