健脾益肾活血法治疗高血压病肾损害临床观察

随着我国老龄人口进程的加快，高血压病的患病率亦逐渐增加，而高血压病肾损害起病隐匿，缓慢进展，严重者出现尿毒症。2011年4月-2013年4月，笔者采用健脾益肾活血法治疗高血压病早期肾损害患者35例，并与对照组35例进行疗效比较观察，现将结果报道如下。     

信息动态

随着维持性血液透析患者甲状旁腺切除术的不断发展与深入,对接受手术的患者实施全面的护理也随之受到重视,需要血液净化中心、内科、外科、监护室、手术室等多护理分支的密切配合与协作.本文就甲状旁腺切除术内科、外科护理要点作一综述.     

粒细胞集落刺激因子在急性髓系白血病治疗中的应用进展

粒细胞集落刺激因子（granulocyte colonysti mulating factor,G-CSF）主要用于各种粒细胞减少症的治疗,如放疗、化疗引起的粒细胞减少、再生障碍性贫血等,还用于干细胞移植、抗感染等治疗。     

对孩子的不良习惯巧说“不”

一日，我带儿子在院子里和其他小朋友玩耍．小朋友里有一个叫贝贝的小女孩儿．长得乖巧可爱，一双黑黝黝的大眼睛闪着顽皮的光芒．她有两岁零四个月了．正让她爸爸带着玩跷跷板呢!     

烧山火手法配合艾柱灸足三里治疗化疗后胃肠反应临床研究

目的：用针灸的手段探讨治疗化疗后胃肠反应的新途径。方法：将化疗病例随机分成对照组与治疗组，治疗组使用烧山火手法针刺足三里后，再用中艾炷灸足三里。对照组使用中艾炷灸足三里。结果：两组有显著差异。结论：烧山火手法配合艾炷灸足三里是治疗化疗后胃肠反应的有效方法之一，且经济实用，简单易行，便于推广。     

胸腔持续负压吸引加高渗葡萄糖灌注进行非手术胸膜固定

目的总结了对一些反复发作的自发性气胸患者采用胸腔持续负压吸引加高渗葡萄糖灌注的方法进行治疗的体会。方法对42例反复发作两次以上的自发性气胸患者先给予胸腔引流管持续负压吸引，然后向胸腔内灌注50％葡萄糖注射液50mL一至三次。结果17例患者在灌注后第二天胸腔引流管中已无气体引出，15例在灌注后第三天漏气停止；8例患者虽仍有气体引出，但气体量明显减少，再次行胸腔灌注后漏气停止；3例患者先后进行灌注三次而痊愈。结论用胸腔持续负压吸引加高渗葡萄糖灌注来治疗进行非手术胸膜固定，是一种风险较小、简便易行、疗效满意的方法，尤其是在技术条件和设备条件差的基层医院，更值得推广。     

应用支持向量机方法对鼻咽癌治疗后5年生存状态的预测

Objective： Support Vector Machine （SVM） is a machine-learning method, based on the principle of structural risk minimization, which performs well when applied to data outside the training set. In this paper, SVM was applied to predict 5-year survival status of patients with nasopharyngeal carcinoma （NPC） after treatment, we expect to find a new way for prognosis studies in cancer so as to assist right clinical decision for individual patient. Methods： Two modelling methods were used in the study; SVM network and a standard parametric logistic regression were used to model 5-year survival status. And the two methods were compared on a prospective set of patients not used in model construction via receiver operating characteristic （ROC） curve analysis. Results： The SVM1, trained with the 25 original input variables without screening, yielded a ROC area of 0.868, at sensitivity to mortality of 79.2% and the specificity of 94.5%. Similarly, the SVM2, trained with 9 input variables which were obtained by optimal input variable selection from the 25 original variables by logistic regression screening, yielded a ROC area of 0.874, at a sensitivity to mortality of 79.2% and the specificity of 95.6%, while the logistic regression yielded a ROC area of 0.751 at a sensitivity to mortality of 66.7% and gave a specificity of 83.5%. Conclusion： SVM found a strong pattern in the database predictive of 5-year survival status. The logistic regression produces somewhat similar, but better, results. These results show that the SVM models have the potential to predict individual patient＇s 5-year survival status after treatment, and to assist the clinicians for making a good clinical decision.     

人OVCA1基因的克隆及其对卵巢癌细胞生长的抑制作用

目的克隆人的OVCA1基因并探讨其对卵巢癌细胞生长的影响。方法从健康人卵巢组织中提取总RNA,采用逆转录酶-聚合酶链反应(RT-PCR)方法扩增OVCA1基因并克隆。脂质体法将含有OVCA1质粒和空载体分别转染入A2780细胞,G418筛选稳定转染细胞。MTT法检测OVCA1对A2780细胞生长的影响。结果测序证实获得了OVCA1基因;过表达OVCA1的细胞与对照组相比,生长速度明显减慢(P<0.05)。结论得到了OVCA1基因克隆;OVCA1在体外明显抑制卵巢癌细胞系A2780的生长。     

枕骨骨肉瘤1例

患者男,23岁.因头痛、头晕伴视力减退1月余入院.查体:神志清,双侧瞳孔等大等圆,光反射存在,听力可,头颅五官无畸形.